Testing effectiveness (Phase 2)Active Not RecruitingNCT04231266What this trial is testingMulti-Center Study of ManNAc for GNE MyopathyWho this might be right forGNE Myopathy Leadiant Biosciences, Inc. 54
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07511556What this trial is testingFirst-in-human Study of UX016 in GNEMWho this might be right forGNE Myopathy Ultragenyx Pharmaceutical Inc 24
Not applicableStudy completedNCT01784679What this trial is testingGNE-Myopathy Disease Monitoring Program (GNEM-DMP): A Registry and Prospective Observational Natural History Study to Assess GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)Who this might be right forHereditary Inclusion Body MyopathyGNE MyopathyNonaka Disease+2 more Ultragenyx Pharmaceutical Inc 319
Large-scale testing (Phase 3)Study completedNCT02377921What this trial is testingPhase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Sialic Acid in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM)Who this might be right forHereditary Inclusion Body MyopathyDistal Myopathy With Rimmed VacuolesDistal Myopathy, Nonaka Type+1 more Ultragenyx Pharmaceutical Inc 89
Testing effectiveness (Phase 2)Ended earlyNCT02731690What this trial is testingEvaluate the Safety of Aceneuramic Acid Extended Release (Ace-ER; UX001) Tablets in Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy (GNEM) (Also Known as Hereditary Inclusion Body Myopathy [HIBM]) Patients With Severe Ambulatory ImpairmentWho this might be right forHereditary Inclusion Body MyopathyDistal Myopathy With Rimmed VacuolesDistal Myopathy, Nonaka Type+3 more Ultragenyx Pharmaceutical Inc 42
Early research (Phase 1)Study completedNCT01236898What this trial is testingPharmacokinetic Study on N-acetylneuraminic AcidWho this might be right forNonaka MyopathyHereditary Inclusion Body Myopathy Tohoku University 6
Testing effectiveness (Phase 2)Study completedNCT01517880What this trial is testingEvaluate the Dose and Pharmacodynamic Efficacy of Sialic Acid-Extended Release (SA-ER) Tablets in Patients With GNE Myopathy or Hereditary Inclusion Body MyopathyWho this might be right forGNE MyopathyHereditary Inclusion Body Myopathy Ultragenyx Pharmaceutical Inc 46
Large-scale testing (Phase 3)Ended earlyNCT02736188What this trial is testingStudy to Evaluate the Safety and Efficacy of Aceneuramic Acid Extended-Release (Ace-ER) Tablets in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM)Who this might be right forHereditary Inclusion Body MyopathyDistal Myopathy With Rimmed VacuolesDistal Myopathy, Nonaka Type+2 more Ultragenyx Pharmaceutical Inc 143
Large-scale testing (Phase 3)Study completedNCT04671472What this trial is testingEfficacy Confirmation Study of NPC-09Who this might be right forGNE MyopathyDistal Myopathy With Rimmed Vacuoles (DMRV)Hereditary Inclusion Body Myopathy (hIBM)+1 more Nobelpharma 14