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Results for “Dornase Alfa”

47 trials

Showing 20 of 47 results

Testing effectiveness (Phase 2)Study completedNCT04785066
What this trial is testing

Efficacy of Pulmozyme® on Arterial Recanalization in Post-thrombectomy Patients Managed for Ischemic Stroke (NETs-target)

Who this might be right for
Ischemic Stroke
Fondation Ophtalmologique Adolphe de Rothschild 39
Large-scale testing (Phase 3)Looking for participantsNCT03368092
What this trial is testing

Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma

Who this might be right for
Multiple TraumaRespiratory Distress Syndrome, Adult
University Hospital, Strasbourg, France 500
Not applicableStudy completedNCT04387786
What this trial is testing

Dornase Alfa Administered to Patients With COVID-19 (DACOVID)

Who this might be right for
COVID-19Mechanical Ventilation
Feinstein Institute for Medical Research 5
Early research (Phase 1)UnknownNCT02135588
What this trial is testing

Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions

Who this might be right for
Loculated or Non-draining Malignant Pleural Effusions
Eastern Regional Medical Center 10
Large-scale testing (Phase 3)Study completedNCT04402970
What this trial is testing

Dornase Alfa for ARDS in Patients With Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)

Who this might be right for
SARS-CoV 2ARDS
University of Missouri-Columbia 30
Large-scale testing (Phase 3)UnknownNCT00204685
What this trial is testing

Time of Ventilation and Lung Function of Ventilated Patients Under Therapy With Dornase Alfa

Who this might be right for
Long Term Ventilation
University Hospital Tuebingen 540
Testing effectiveness (Phase 2)Ended earlyNCT02193490
What this trial is testing

DNase Treatment for Dry Eyes

Who this might be right for
Dry Eye
University of Illinois at Chicago 47
Testing effectiveness (Phase 2)Study completedNCT00117208
What this trial is testing

Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis

Who this might be right for
Cystic Fibrosis
Syntara 20
Testing effectiveness (Phase 2)UnknownNCT02722122
What this trial is testing

Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Exploratory Efficacy Parameters of AIR DNase™in Patients With Cystic Fibrosis Previously Treated With Pulmozyme®

Who this might be right for
Cystic Fibrosis
Protalix 15
Post-approval studies (Phase 4)Study completedNCT02168387
What this trial is testing

Efficacy of Percussive Ventilation Therapy (MetaNeb ®) Compared With Mucolytic Agents for Atelectasis in the Mechanically Ventilated Pediatric Patient

Who this might be right for
Atelectasis
Duke University 39
Not applicableStudy completedNCT01095276
What this trial is testing

Impact of Nebulized Dornase Alpha on Mechanically Ventilated Patients

Who this might be right for
AtelectasisVentilation, Mechanical
University of Medicine and Dentistry of New Jersey 30
Not applicableStudy completedNCT00311506
What this trial is testing

Determine the Variability of a 6-Minute Walk Test in Cystic Fibrosis Subjects With Advanced Lung Disease

Who this might be right for
Cystic Fibrosis
Genentech, Inc. 25
Very early researchUnknownNCT00536952
What this trial is testing

Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy

Who this might be right for
Head and Neck Cancer
Northwestern University 36
Large-scale testing (Phase 3)Ended earlyNCT04355364
What this trial is testing

Efficacy and Safety of aerosolizedDornase Alfa Administration in Patients With COVID19 Induced ARDS (COVIDORNASE)

Who this might be right for
COVID-19Acute Respiratory Distress Syndrome
Fondation Ophtalmologique Adolphe de Rothschild 77
Post-approval studies (Phase 4)Study completedNCT01712334
What this trial is testing

The Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer System in Patients With Cystic Fibrosis

Who this might be right for
Cystic Fibrosis
Genentech, Inc. 99
Post-approval studies (Phase 4)Ended earlyNCT00434278
What this trial is testing

A Trial of Pulmozyme Withdrawal on Exercise Tolerance in Cystic Fibrosis Subjects With Severe Lung Disease (TOPIC)

Who this might be right for
Cystic Fibrosis
Genentech, Inc. 27
Testing effectiveness (Phase 2)Study completedNCT05203224
What this trial is testing

Improving Early Reperfusion With Adjuvant Dornase Alfa in Large Vessel Ischemic Stroke (EXTEND-IA DNase)

Who this might be right for
Ischemic Stroke
University of Melbourne 330
Not applicableStudy completedNCT00671723
What this trial is testing

Dornase Alpha Versus Hypertonic Saline for Lung Atelectasis in Non-Cystic Fibrosis Patients

Who this might be right for
Atelectasis
University of Oklahoma 33
Post-approval studies (Phase 4)Ended earlyNCT00680316
What this trial is testing

Pulmozyme® (Dornase Alpha) in 3- to 5-Year-Old Patients With Cystic Fibrosis

Who this might be right for
Cystic Fibrosis
Genentech, Inc. 3
Not applicableStudy completedNCT04915586
What this trial is testing

Short Duration High Intensity Intrapleural Alteplase With Pulmozyme in Pleural Infection Management

Who this might be right for
Loculated Empyema
National University of Malaysia 30
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