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Results for “Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma”

21 trials

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Showing 20 of 21 results

Early research (Phase 1)Study completedNCT03739931
What this trial is testing

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Who this might be right for
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or LymphomaDose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
ModernaTX, Inc. 134
Early research (Phase 1)UnknownNCT05564806
What this trial is testing

Study of YH004 (4-1BB Agonist Antibody) in Advanced Solid Tumors And Relapsed Or Refractory Non-Hodgkin Lymphoma

Who this might be right for
Advanced Solid TumorsRelapsed Or Refractory Non-Hodgkin Lymphoma
Eucure (Beijing) Biopharma Co., Ltd 38
Early research (Phase 1)Study completedNCT04349969
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK117 as Monotherapy or in Combination With AK104

Who this might be right for
Neoplasms Malignant
Akesobio Australia Pty Ltd 38
Early research (Phase 1)WithdrawnNCT02800889
What this trial is testing

Dose-Escalation Study of Pixantrone Monotherapy in Pediatric Patients With Relapsed or Refractory Cancer

Who this might be right for
LymphomaSolid Tumor (Excluding CNS)
CTI BioPharma
Early research (Phase 1)Looking for participantsNCT06487624
What this trial is testing

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Who this might be right for
Advanced Solid TumorRefractory Hodgkin Lymphoma
FBD Biologics Limited 50
Early research (Phase 1)Ended earlyNCT02408861
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmAnal CarcinomaHIV Infection+7 more
National Cancer Institute (NCI) 79
Early research (Phase 1)Study completedNCT05040932
What this trial is testing

Study of YH004 (4-1BB Agonist Antibody) in Advanced or Metastatic Malignancy

Who this might be right for
Cancer
Eucure (Beijing) Biopharma Co., Ltd 8
Testing effectiveness (Phase 2)UnknownNCT04458389
What this trial is testing

TY101 for Locally Advanced /Metastatic Solid Tumors and Relapsed or Refractory Lymphomas

Who this might be right for
Locally Advanced /Metastatic Solid TumorsRelapsed or Refractory Lymphomas
Tayu Huaxia Biotech Medical Group Co., Ltd. 268
Early research (Phase 1)Ended earlyNCT03403725
What this trial is testing

MEN1309 I.v. Infusion in Pts With CD205-positive Metastatic Solid Tumors and Relapsed or Refractory NHL Ph I Study

Who this might be right for
Metastatic Solid TumorsRelapsed/Refractory Non-Hodgkin Lymphoma
Menarini Group 28
Early research (Phase 1)Looking for participantsNCT05607498
What this trial is testing

First in Human Study of EMB-07 in Locally Advanced/Metastatic Solid Tumors or Relapse/Refractory Lymphoma

Who this might be right for
Advanced/Metastatic Solid TumorsRelapse/Refractory Lymphoma
EpimAb Biotherapeutics (Suzhou)Co., Ltd. 150
Early research (Phase 1)Looking for participantsNCT06132503
What this trial is testing

Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors

Who this might be right for
Relapsed or Refractory LymphomasAdvanced Solid Tumor
Lantern Pharma Inc. 110
Early research (Phase 1)Study completedNCT05225584
What this trial is testing

Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

Who this might be right for
Non Hodgkin Lymphoma (NHL)Peripheral T-cell Lymphoma (PTCL)Cutaneous T-Cell Lymphoma (CTCL)+3 more
Kymera Therapeutics, Inc. 56
Early research (Phase 1)Study completedNCT00036946
What this trial is testing

VEGF Trap in Treating Patients With Relapsed or Refractory Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
LymphomaUnspecified Adult Solid Tumor, Protocol Specific
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)Ended earlyNCT03323398
What this trial is testing

Dose Escalation and Efficacy Study of mRNA-2416 for Intratumoral Injection Alone and in Combination With Durvalumab for Participants With Advanced Malignancies

Who this might be right for
Relapsed/Refractory Solid Tumor Malignancies or LymphomaOvarian Cancer
ModernaTX, Inc. 79
Testing effectiveness (Phase 2)Ended earlyNCT03648372
What this trial is testing

TAK-981 in People With Advanced Solid Tumors or Cancers in the Immune System

Who this might be right for
NeoplasmsLymphomaHematologic Neoplasms
Takeda 109
Early research (Phase 1)Study completedNCT00083213
What this trial is testing

Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Cancer
Regeneron Pharmaceuticals 25
Early research (Phase 1)Study completedNCT01460134
What this trial is testing

CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers

Who this might be right for
CD27 Expressing B-cell Malignancies for Example Hodgkin's LymphomaChronic Lymphocytic LeukemiaMantle Cell Lymphoma+7 more
Celldex Therapeutics 90
Early research (Phase 1)Study completedNCT03205176
What this trial is testing

AZD5153 in Patients With Relapsed or Refractory Solid Tumors, Including Lymphomas

Who this might be right for
Malignant Solid TumorsLymphomaOvarian Cancer+3 more
AstraZeneca 49
Early research (Phase 1)Ended earlyNCT02663518
What this trial is testing

A Trial of PF-07901800 (TTI-621) for Patients With Hematologic Malignancies and Selected Solid Tumors

Who this might be right for
Hematologic MalignanciesSolid Tumor
Pfizer 249
Testing effectiveness (Phase 2)Ended earlyNCT04718675
What this trial is testing

KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

Who this might be right for
Relapsed Solid TumorsRefractory Solid TumorsNon-Hodgkin Lymphoma+2 more
Kronos Bio 135
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