Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Dose Escalation and Safety”

4,243 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 4,243 results

Early research (Phase 1)Looking for participantsNCT06994806
What this trial is testing

Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Who this might be right for
Solid Tumor Malignancies
Kumquat Biosciences Inc. 84
Early research (Phase 1)Study completedNCT02896868
What this trial is testing

LY3041658 in Participants With Skin Diseases

Who this might be right for
Skin DiseasesPsoriasis
Eli Lilly and Company 60
Early research (Phase 1)Study completedNCT04328740
What this trial is testing

Phase 1 Study of Oral TP-1454

Who this might be right for
Advanced Solid TumorAnal Cancer
Sumitomo Pharma America, Inc. 31
Early research (Phase 1)Looking for participantsNCT05217693
What this trial is testing

A First-in-human of Multiplle Doses of BB-1705 in Subjects With Locally Advanced/Metastatic Solid Tumors

Who this might be right for
Solid Tumor
Bliss Biopharmaceutical (Hangzhou) Co., Ltd 288
Early research (Phase 1)UnknownNCT05765006
What this trial is testing

CD19-CART(Relma-cel) for Moderate to Severe Active Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus
Shanghai Ming Ju Biotechnology Co., Ltd. 24
Early research (Phase 1)Study completedNCT01934738
What this trial is testing

Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)

Who this might be right for
Healthy
Pfizer 52
Early research (Phase 1)Ended earlyNCT02040558
What this trial is testing

Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Mallinckrodt 44
Early research (Phase 1)Study completedNCT01849055
What this trial is testing

A Multiple Dose Study of LY3023703 in Healthy Participants

Who this might be right for
Healthy Volunteers
Eli Lilly and Company 48
Large-scale testing (Phase 3)Looking for participantsNCT07426055
What this trial is testing

PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer

Who this might be right for
Prostate Cancer (Adenocarcinoma)Prostate BrachytherapyStereotactic Body Radiation Therapy (SBRT)+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy 1,000
Testing effectiveness (Phase 2)Study completedNCT05410743
What this trial is testing

Evaluation of 177Lu-TATE-EB-01(LNC1010)in SSTR2-positive Tumors

Who this might be right for
SSTR2-positive Tumors
The First Affiliated Hospital of Xiamen University 30
Very early researchLooking for participantsNCT07558538
What this trial is testing

A Single Dose, Dose Escalation Clinical Trial on the Safety, Tolerability and Efficacy of Lyophilized Powder for Inhalation of Recombinant Human Keratinocyte Growth Factor-2 (Rh-KGF-2) in The Treatment of Patients With Acute Respiratory Distress Syndrome

Who this might be right for
ARDS (Moderate or Severe)ARDS (Acute Respiratory Distress Syndrome)
Shanghai Zhongshan Hospital 24
Early research (Phase 1)Looking for participantsNCT06535308
What this trial is testing

BnH-015B Clinical Trial in Moderate Alzheimer's Disease

Who this might be right for
Alzheimer Disease
BnH Research 92
Post-approval studies (Phase 4)Study completedNCT00949884
What this trial is testing

Olmesartan Comparison to Losartan in Hypertensive Subjects

Who this might be right for
Hypertension
Daiichi Sankyo 941
Large-scale testing (Phase 3)Ended earlyNCT05288855
What this trial is testing

Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis

Who this might be right for
Adolescent Lupus NephritisPediatric Lupus Nephritis
Aurinia Pharmaceuticals Inc. 9
Early research (Phase 1)Study completedNCT02572635
What this trial is testing

A Phase I Study to Evaluate the Safety and Immunogenicity of PnuBioVax

Who this might be right for
Pneumococcal Infection
ImmunoBiology Limited 36
Testing effectiveness (Phase 2)WithdrawnNCT06147856
What this trial is testing

A Dose-finding Study to Evaluate mRNA-3210 in Participants With Phenylketonuria

Who this might be right for
Phenylketonuria
ModernaTX, Inc.
Early research (Phase 1)UnknownNCT03427853
What this trial is testing

Evaluate the Denosumab in Healthy Adults

Who this might be right for
Healthy Adults
Luye Pharma Group Ltd. 32
Early research (Phase 1)Study completedNCT01335256
What this trial is testing

Clinical Study to Evaluate Safety and Maximum Tolerated Dose of BAY1000394 Given in a 4 Week on / 2 Week Off Schedule in Subjects With Advanced Malignancies

Who this might be right for
Neoplasms
Bayer 10
Early research (Phase 1)Looking for participantsNCT07500181
What this trial is testing

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BAL2420 in Healthy Adult Subjects

Who this might be right for
Healthy
Basilea Pharmaceutica 136
Early research (Phase 1)Study completedNCT02658253
What this trial is testing

Trial to Evaluate the Safety and Immunogenicity of a Placental Malaria Vaccine Candidate (PRIMVAC ) in Healthy Adults

Who this might be right for
Malaria
Institut National de la Santé Et de la Recherche Médicale, France 68
Next Page