Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Dose Escalation and Safety”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT02492737
What this trial is testing

Study of Orally Administered AG-881 in Patients With Advanced Hematologic Malignancies With an IDH1 and/or IDH2 Mutation

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic SyndromeHematologic Malignancies
Agios Pharmaceuticals, Inc. 46
Early research (Phase 1)Study completedNCT01976741
What this trial is testing

Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)

Who this might be right for
Neoplasms
Bayer 168
Testing effectiveness (Phase 2)Study completedNCT03370172
What this trial is testing

BAX 888 in Male Adults With Severe Hemophilia A

Who this might be right for
Hemophilia A
Baxalta now part of Shire 4
Early research (Phase 1)Looking for participantsNCT07501039
What this trial is testing

BLKR201 in Healthy Adult Participants

Who this might be right for
Healthy
Formation Bio, Inc. 128
Early research (Phase 1)UnknownNCT05783570
What this trial is testing

To Evaluate the Safety, Tolerability and Preliminary Efficacy of EU307

Who this might be right for
Advanced Hepatocellular Carcinoma
Eutilex 12
Early research (Phase 1)UnknownNCT05536427
What this trial is testing

Safety and Efficacy of IPM001 in Patients With Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Peking Union Medical College Hospital 24
Early research (Phase 1)Not Yet RecruitingNCT06287918
What this trial is testing

A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations

Who this might be right for
Solid Tumors With FGFR2 Alterations, Adult
3H (Suzhou) Pharmaceuticals Co., Ltd. 130
Early research (Phase 1)Ended earlyNCT01908413
What this trial is testing

Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-427 When Given to Patients With Advanced and Refractory Solid Tumors or Lymphoma

Who this might be right for
Lymphoma
Curis, Inc. 23
Early research (Phase 1)Study completedNCT04283461
What this trial is testing

Safety and Immunogenicity Study of 2019-nCoV Vaccine (mRNA-1273) for Prophylaxis of SARS-CoV-2 Infection (COVID-19)

Who this might be right for
COVID-19COVID-19 Immunisation
National Institute of Allergy and Infectious Diseases (NIAID) 120
Early research (Phase 1)Study completedNCT01378091
What this trial is testing

Study of Lenalidomide and Docetaxel in Subjects With Androgen Independent Prostate Cancer

Who this might be right for
Prostate Cancer
Columbia University 64
Testing effectiveness (Phase 2)Study completedNCT01674569
What this trial is testing

Pilot Study of X-82 in Patients With Wet AMD

Who this might be right for
Exudative Macular Degeneration
Tyrogenex 35
Early research (Phase 1)Study completedNCT03632291
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UB-221 as an Add-on Therapy in CSU Patients

Who this might be right for
Urticaria Chronic
United BioPharma 15
Early research (Phase 1)Active Not RecruitingNCT06645886
What this trial is testing

Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Hematologic Malignancies

Who this might be right for
Hematologic MalignanciesAdult
Kumquat Biosciences Inc. 13
Early research (Phase 1)Study completedNCT03212586
What this trial is testing

BAY 1902607: Single Dose Escalation, Safety and Tolerability, Pharmacokinetics, Bioavailability, Food Effect

Who this might be right for
Clinical Trials, Phase I as Topic
Bayer 72
Not applicableActive Not RecruitingNCT07617779
What this trial is testing

The Safety and Preliminary Efficacy of NKG001 in Pediatric Patients With Type 1 or Type 2 Spinal Muscular Atrophy

Who this might be right for
Spinal Muscular Atrophy (SMA)
Nikegen Pharmaceutical (Hangzhou) Company Limited 21
Early research (Phase 1)Study completedNCT01918735
What this trial is testing

The Safety and Tolerability of GWP42006 in Healthy Subjects

Who this might be right for
Epilepsy
Jazz Pharmaceuticals 66
Early research (Phase 1)Study completedNCT00923520
What this trial is testing

A Phase 1, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612) in Advanced Malignancies

Who this might be right for
Renal Cell CarcinomaBreast CancerColon Cancer+2 more
National Cancer Institute (NCI) 60
Early research (Phase 1)Study completedNCT00734188
What this trial is testing

Dose Escalation and Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Pain Therapeutics 21
Early research (Phase 1)Study completedNCT05712889
What this trial is testing

Phase 1 Dose Escalation Study for VIP236 in Patients With Advanced Cancer

Who this might be right for
Neoplasms
Vincerx Pharma, Inc. 29
Early research (Phase 1)Active Not RecruitingNCT06074497
What this trial is testing

This is an Open Label, Two-part, Multicenter, Phase I Trial to Investigate the Safety, Tolerability, and PK of KGX101 Monotherapy and Combination Therapy With Envafolimab in Patients With Advanced or Metastatic Solid Tumors.

Who this might be right for
Advanced or Metastatic Solid Tumors
Kangabio AUSTRALIA LTD PTY 54
Next Page