Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Dose Escalation and Safety”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Ended earlyNCT03144661
What this trial is testing

An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies

Who this might be right for
Hepatocellular Carcinoma (HCC)CholangiocarcinomaEsophageal Cancer+3 more
Incyte Corporation 25
Early research (Phase 1)Study completedNCT05563454
What this trial is testing

Learn How Safe the Study Treatment BAY2395840 is, How it Affects the Body and How it Moves Into, Through, and Out of the Body if Given in Single and in Repetitive Doses to Japanese Healthy Male Participants

Who this might be right for
Diabetic Neuropathic PainHealthy Volunteers
Bayer 24
Large-scale testing (Phase 3)Study completedNCT01565694
What this trial is testing

Assess the Long Term Effect, Safety and Metabolism of a Solifenacin Liquid Suspension in Participants 5 to 18 Years of Age With Neurogenic Detrusor Overactivity

Who this might be right for
Neurogenic Detrusor Overactivity
Astellas Pharma Europe B.V. 76
Early research (Phase 1)Study completedNCT01892046
What this trial is testing

Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors

Who this might be right for
Cancer
Esanex Inc. 18
Early research (Phase 1)Study completedNCT05017870
What this trial is testing

[KSR-001-P01]Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristic of KSR-001

Who this might be right for
Dry Eye Syndromes
Kukje Pharma 24
Early research (Phase 1)Study completedNCT01837641
What this trial is testing

LY3002813 in Participants With Alzheimer's Disease

Who this might be right for
Alzheimer Disease
Eli Lilly and Company 63
Early research (Phase 1)Study completedNCT01564251
What this trial is testing

GDC-0575 Alone and in Combination With Gemcitabine in Participants With Refractory Solid Tumors or Lymphoma

Who this might be right for
Lymphoma, Solid Tumor
Genentech, Inc. 104
Early research (Phase 1)Study completedNCT00829582
What this trial is testing

Intravenous Dose-Escalation Study With ETI-204 in Adult Volunteers

Who this might be right for
Healthy Volunteers
Elusys Therapeutics 45
Early research (Phase 1)UnknownNCT05554666
What this trial is testing

ASKG315 in Patients With Advanced Solid Tumors.

Who this might be right for
Advanced Solid Tumors
AskGene Pharma, Inc. 56
Early research (Phase 1)Study completedNCT03334851
What this trial is testing

Safety and Tolerability Study Of PF-06835375 In Subjects With Seropositive Systemic Lupus Erythematosus Or Rheumatoid Arthritis

Who this might be right for
Systemic Lupus ErythematosusRheumatoid Arthritis
Pfizer 74
Early research (Phase 1)Active Not RecruitingNCT06816108
What this trial is testing

ONO-7428 in Participants With Unresectable Advanced or Recurrent Solid Tumors

Who this might be right for
Solid TumorNSCLC
Ono Pharmaceutical Co., Ltd. 35
Early research (Phase 1)Ended earlyNCT03685591
What this trial is testing

PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors

Who this might be right for
Breast NeoplasmsProstate NeoplasmsNeoplasms, Squamous Cell+6 more
Pfizer 49
Early research (Phase 1)Study completedNCT04385420
What this trial is testing

Phase 1 Study of ATR-002

Who this might be right for
Influenza
Atriva Therapeutics GmbH 70
Early research (Phase 1)Study completedNCT01340040
What this trial is testing

Dose-escalation Study to Assess Safety, Tolerability and Pharmacokinetics of MEDI-573 in Japanese Subjects

Who this might be right for
CancerAdvanced Solid Malignancies
AstraZeneca 10
Early research (Phase 1)Study completedNCT02723240
What this trial is testing

NUC-3373 in Advanced Solid Tumours

Who this might be right for
Cancer
University of Oxford 62
Testing effectiveness (Phase 2)Study completedNCT04578210
What this trial is testing

Safety Infusion of NatuRal KillEr celLs or MEmory T Cells as Adoptive Therapy in COVID-19 pnEumonia or Lymphopenia

Who this might be right for
Corona Virus Infection
Instituto de Investigación Hospital Universitario La Paz 84
Early research (Phase 1)Study completedNCT00960960
What this trial is testing

PI3-Kinase Inhibitor GDC-0941 in Combination With Paclitaxel, With and Without Bevacizumab or Trastuzumab, and With Letrozole, in Participants With Locally Recurrent or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Genentech, Inc. 71
Early research (Phase 1)Study completedNCT04135560
What this trial is testing

Determine The Safety, Tolerability, Skin Irritation Potential, And PK Following Topical Application Of PF-07038124 In Healthy Participants

Who this might be right for
Dermatitis Atopic
Pfizer 34
Early research (Phase 1)Looking for participantsNCT06994676
What this trial is testing

CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

Who this might be right for
High-risk Myelodysplastic SyndromeChronic Myelomonocytic Leukemia (CMML)AML - Acute Myeloid Leukemia+1 more
Crossbow Therapeutics, Inc. 72
Early research (Phase 1)Study completedNCT00503490
What this trial is testing

Safety, Pharmacokinetic and Pharmacodynamic Study of MP-376 in Patients With Cystic Fibrosis

Who this might be right for
Cystic Fibrosis
Amgen 40
Next Page