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Results for “Down Syndrome (DS)”

46 trials

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Showing 20 of 46 results

Post-approval studies (Phase 4)Not Yet RecruitingNCT06911944
What this trial is testing

Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation

Who this might be right for
Down Syndrome (DS)Down Syndrome (Trisomy 21)Alzheimer Disease+1 more
Michael Rafii, MD, PhD 60
Early research (Phase 1)Not Yet RecruitingNCT07278492
What this trial is testing

NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome

Who this might be right for
Down Syndrome (DS)
Brigham and Women's Hospital 24
Not applicableStudy completedNCT00695695
What this trial is testing

The Experience of Caregivers of Children With Down Syndrome

Who this might be right for
Down Syndrome
National Human Genome Research Institute (NHGRI) 546
Not applicableStudy completedNCT05310552
What this trial is testing

Elucidating Age-related Comorbidity Patterns in Down Syndrome (DS)

Who this might be right for
Down Syndrome
King's College London 230
Large-scale testing (Phase 3)Ended earlyNCT06860373
What this trial is testing

LIFE-DSR-Biomarker Sub-study of Biomarkers in Down Syndrome Related Alzheimer's Disease (DS-AD)

Who this might be right for
Down Syndrome
LuMind IDSC Foundation 5
Not applicableStudy completedNCT05312177
What this trial is testing

Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)

Who this might be right for
Down SyndromeCongenital Heart Disease
Carelon Research 273
Not applicableLooking for participantsNCT07425769
What this trial is testing

Adapting RDAD for DS

Who this might be right for
Down Syndrome (DS)Alzheimer's Disease (AD)
University of Kansas Medical Center 40
Early research (Phase 1)Ended earlyNCT06673069
What this trial is testing

Hero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) and Pharmacodynamics (PD) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer's Disease (AD)

Who this might be right for
Alzheimer DiseaseDown Syndrome
Ionis Pharmaceuticals, Inc. 1
Not applicableStudy completedNCT03624556
What this trial is testing

Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS)

Who this might be right for
Down SyndromeFragile X Syndrome
Parc de Salut Mar 76
Not applicableStudy completedNCT07534085
What this trial is testing

Effects of a Structured Physical Activity Program on Balance and Functional Performance in Children With Down Syndrome

Who this might be right for
Down Syndrome (DS)Balance AssessmentPhysical Activities+2 more
Ankara University 15
Not applicableStudy completedNCT02759887
What this trial is testing

Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD)

Who this might be right for
Down SyndromeAlzheimer's Dementia
St. Joseph's Hospital and Medical Center, Phoenix 19
Large-scale testing (Phase 3)Looking for participantsNCT07135167
What this trial is testing

Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome

Who this might be right for
Down Syndrome (DS)KeratoconusPellucid Marginal Degeneration+1 more
Woolfson Eye Institute 225
Not applicableStudy completedNCT05191654
What this trial is testing

Investigation of Cardiopulmonary Parameters, Motor Development and Muscle Strength in DS With and Without CHD

Who this might be right for
Congenital Heart DefectsDown SyndromeGross Motor Development Delay
Atılım University 28
Not applicableLooking for participantsNCT07213063
What this trial is testing

Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome

Who this might be right for
Down Syndrome (DS)Supplementation
Universidad de Burgos 50
Not applicableLooking for participantsNCT06748248
What this trial is testing

Suspension Therapy Effects on Mobility and Balance in Down Syndrome

Who this might be right for
Down Syndrome (DS)
Riphah International University 26
Not applicableLooking for participantsNCT05702645
What this trial is testing

Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia Associated With Down SyndromeDown SyndromeMyeloid Leukemia Associated With Down Syndrome
Children's Oncology Group 330
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07636811
What this trial is testing

Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)

Who this might be right for
Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Alnylam Pharmaceuticals 58
Not applicableLooking for participantsNCT01950624
What this trial is testing

DS-Connect®: The Down Syndrome Registry

Who this might be right for
Down Syndrome
University of Colorado, Denver 100,000
Not applicableLooking for participantsNCT07248449
What this trial is testing

Physical Fitness in DS: A Comparison of Cuevas Medak and Rebound Exercises

Who this might be right for
Down Syndrome
Riphah International University 22
Not applicableLooking for participantsNCT06851338
What this trial is testing

Pediatric Down Syndrome Post-Approval Study

Who this might be right for
Pediatric Obstructive Sleep ApneaDown Syndrome (DS)
Inspire Medical Systems, Inc. 60
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