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Results for “Drug Metabolism and Pharmacokinetics”

247 trials

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Showing 20 of 247 results

Early research (Phase 1)Not Yet RecruitingNCT06727838
What this trial is testing

Study on Drug Interaction of Metformin Tablets and HRS-7535 Tablets in Healthy Human

Who this might be right for
Diabetes
Shandong Suncadia Medicine Co., Ltd. 54
Not applicableStudy completedNCT01923363
What this trial is testing

PK/PD of High Dose Pip/Tazo in Obese Patients

Who this might be right for
Obesity
Loma Linda University 29
Early research (Phase 1)Study completedNCT01145885
What this trial is testing

BI 6727 (Volasertib) Human ADME Trial in Various Solid Tumours

Who this might be right for
Neoplasms
Boehringer Ingelheim 7
Early research (Phase 1)Study completedNCT05981963
What this trial is testing

Evaluate the Drug Levels, Physical and Chemical Changes, and Removal of BMS-986196 in Healthy Male Participants

Who this might be right for
Healthy Male Volunteers
Bristol-Myers Squibb 8
Early research (Phase 1)Study completedNCT00501397
What this trial is testing

The Effects of Ketoconazole Taken Orally Has on the PK Profiles of a Dose of GSK189075 in Healthy Volunteers

Who this might be right for
Type 2 Diabetes MellitusDiabetes Mellitus, Type 2
GlaxoSmithKline 22
Post-approval studies (Phase 4)Study completedNCT02401256
What this trial is testing

CYP2B6 Genetics and Drug Interactions in Healthy Volunteers

Who this might be right for
Healthy
Indiana University 70
Early research (Phase 1)WithdrawnNCT01214122
What this trial is testing

A Drug-Drug Interaction Study Between AZD9668 and Warfarin to Study the Effect of AZD9668 on the Metabolism and Effect of Warfarin

Who this might be right for
PharmacokineticsPharmacodynamics
AstraZeneca
Not applicableLooking for participantsNCT05981573
What this trial is testing

Assessment of Methadone Dose Taken

Who this might be right for
Methadone ToxicityMethadone OverdosePain, Chronic+2 more
Cari Health Inc. 30
Early research (Phase 1)UnknownNCT03867942
What this trial is testing

BE Study of Bilayer Combination of Gemigliptin/Rosuvastatin 50/20mg in Comparison to Monolayer Combination.

Who this might be right for
Diabetes Mellitus, Type 2Dyslipidemias
LG Chem 48
Testing effectiveness (Phase 2)Study completedNCT03818256
What this trial is testing

Assess the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adults With Schizophrenia or Bipolar Disorder Treated With Antipsychotic Medications

Who this might be right for
Antipsychotic-induced Weight Gain (AIWG)
Corcept Therapeutics 71
Early research (Phase 1)Study completedNCT03305471
What this trial is testing

DS2330b Alone and With Sevelamer in Patients on Chronic Hemodialysis

Who this might be right for
Hyperphosphatemia
Daiichi Sankyo 40
Early research (Phase 1)Study completedNCT02772601
What this trial is testing

This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis

Who this might be right for
Psoriasis
AbbVie 21
Early research (Phase 1)Looking for participantsNCT07090824
What this trial is testing

Subcutaneous Pharmacokinetic Evaluation of Monomeric Insulin and Lyumjev in Adults With Type 1 Diabetes

Who this might be right for
Diabetes Mellitus, Type 1Type 1 Diabetes Mellitus
Stanford University 20
Early research (Phase 1)Study completedNCT04142424
What this trial is testing

Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693, in Subjects of Non-Childbearing Potential in Overweight But Otherwise Healthy Subjects, and Healthy Chinese and Japanese Subjects

Who this might be right for
Metabolic DisordersNon-alcoholic Steatohepatitis
AstraZeneca 73
Early research (Phase 1)Ended earlyNCT04764851
What this trial is testing

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates

Who this might be right for
Drug-Interactions
Emalex Biosciences Inc. 30
Early research (Phase 1)Study completedNCT05787002
What this trial is testing

Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.

Who this might be right for
Dyslipidemia
AstraZeneca 16
Early research (Phase 1)Looking for participantsNCT07343960
What this trial is testing

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

Who this might be right for
Moderate Hepatic Impairment
AstraZeneca 20
Testing effectiveness (Phase 2)Study completedNCT04524403
What this trial is testing

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Obese Adult Patients With Schizophrenia While Taking Antipsychotic Medications (GRATITUDE II)

Who this might be right for
Antipsychotic-induced Weight Gain (AIWG)
Corcept Therapeutics 150
Not applicableStudy completedNCT02993861
What this trial is testing

Pharmacokinetics of Anti-epileptic Drugs in Obese Children

Who this might be right for
EpilepsyObese
Christoph P Hornik, MD MPH 106
Early research (Phase 1)Study completedNCT03723772
What this trial is testing

A Research Study of How Different Doses of a New Medicine NNC0148-0287 C (Insulin 287) Work on the Blood Sugar in People With Type 1 Diabetes When it is Taken Once a Week

Who this might be right for
Diabetes Mellitus, Type 1
Novo Nordisk A/S 66
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