Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Drug-resistant Depression”

60 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 60 results

Testing effectiveness (Phase 2)Looking for participantsNCT06524830
What this trial is testing

Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

Who this might be right for
Treatment Resistant Depression
atai Therapeutics, Inc. 142
Testing effectiveness (Phase 2)Looking for participantsNCT06511908
What this trial is testing

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

Who this might be right for
SuicideDepressive Disorder, Treatment-ResistantKetamine+10 more
National Institute of Mental Health (NIMH) 50
Testing effectiveness (Phase 2)Study completedNCT04979910
What this trial is testing

Targeting IL-17A for Treatment-Resistant Depression

Who this might be right for
Major Depressive Disorder
Icahn School of Medicine at Mount Sinai 7
Testing effectiveness (Phase 2)Ended earlyNCT04141904
What this trial is testing

Tofacitinib in Depression (TIDE)

Who this might be right for
DepressionInflammation
University of Oxford 2
Not applicableStudy completedNCT06232291
What this trial is testing

Observation of Safety and Tolerability Within 1 Year of the Use of R-ketamine / Placebo in Drug-resistant Depression

Who this might be right for
Treatment-Resistant DepressionMajor Depressive Disorder
Medical University of Gdansk 3
Not applicableStudy completedNCT05243160
What this trial is testing

Medication Reviews in Severe Mental Illness

Who this might be right for
SchizophreniaDiabetesMetabolic Syndrome+5 more
Psychiatric Research Unit, Region Zealand, Denmark 48
Not applicableLooking for participantsNCT06049420
What this trial is testing

Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients

Who this might be right for
ObesityHyperlipidemiasPolycystic Ovary Syndrome+6 more
West Virginia School of Osteopathic Medicine 95
Early research (Phase 1)Study completedNCT02577250
What this trial is testing

Ketamine Infusions for PTSD and Treatment-Resistant Depression

Who this might be right for
Depressive Disorder, Treatment-ResistantStress Disorders, Post-Traumatic
Minneapolis Veterans Affairs Medical Center 20
Not applicableStudy completedNCT00000376
What this trial is testing

Cognitive and Drug Therapy for Drug-Resistant Depression

Who this might be right for
DepressionAnxiety DisordersPersonality Disorders+1 more
University of Pennsylvania
Not applicableStudy completedNCT03105700
What this trial is testing

Low Frequency TMS for Depression in Epilepsy

Who this might be right for
EpilepsyDepressions, Refractory
Dartmouth-Hitchcock Medical Center 15
Not applicableStudy completedNCT06754124
What this trial is testing

Investigation of the Effects of Pilates Training in Patients With Drug-Resistant Epilepsy

Who this might be right for
EpilepsyCognitive DysfunctionSeizures+3 more
Recep Tayyip Erdogan University Training and Research Hospital 30
Testing effectiveness (Phase 2)Study completedNCT01527981
What this trial is testing

Cognitive Behavioral Therapy (CBT) for Adherence and Depression in Type 1 Diabetes

Who this might be right for
DepressionType 1 Diabetes
Massachusetts General Hospital 9
Testing effectiveness (Phase 2)UnknownNCT04171193
What this trial is testing

Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent

Who this might be right for
Depressive Disorder, MajorTreatment Resistant DepressionDepressive Episode
University of Sao Paulo 30
Not applicableStudy completedNCT00901407
What this trial is testing

Lamotrigine Augmentation in Resistant Depression

Who this might be right for
Unipolar Depression
Louisiana State University Health Sciences Center in New Orleans 138
Not applicableUnknownNCT03244345
What this trial is testing

Depression, Stress and Vulnerability Factors in Drug Resistant Focal Epilepsies

Who this might be right for
Depression and Epilepsy
Assistance Publique Hopitaux De Marseille 150
Not applicableStudy completedNCT05177146
What this trial is testing

Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression

Who this might be right for
Bipolar Disorder (BD)Suicidality
Centre for Addiction and Mental Health 16
Not applicableStudy completedNCT03556735
What this trial is testing

Pulsed Electro Magnetic Fields (PEMF) in Depression

Who this might be right for
Depression, Unipolar
University of Southern Denmark 59
Testing effectiveness (Phase 2)Study completedNCT00577070
What this trial is testing

Evaluation of the H-Coil Transcranial Magnetic Stimulation(TMS) Device- Augmentation for Drug Resistant Depression

Who this might be right for
Major Depression
BeerYaakov Mental Health Center 40
Early research (Phase 1)Study completedNCT01546051
What this trial is testing

BCI-838 and Several BCI-632 Prodrugs in Healthy Volunteers

Who this might be right for
Healthy
BrainCells Inc. 31
Not applicableEnded earlyNCT02863380
What this trial is testing

Personalized rTMS for Resistant Depression

Who this might be right for
Depressive DisorderTreatment-Resistant
University Hospital, Strasbourg, France 27
Next Page