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Results for “Duplication”

83 trials

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Showing 20 of 83 results

Not applicableStudy completedNCT01052688
What this trial is testing

Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies

Who this might be right for
Down SyndromeAneuploidy
Sequenom, Inc. 150
Large-scale testing (Phase 3)Study completedNCT02039726
What this trial is testing

(QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Who Are FLT3-ITD Positive

Who this might be right for
AML
Daiichi Sankyo 367
Not applicableLooking for participantsNCT01429389
What this trial is testing

Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

Who this might be right for
Down SyndromeFetal Aneuploidy
Sequenom, Inc. 2,000
Early research (Phase 1)Active Not RecruitingNCT03513484
What this trial is testing

Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2AFibroblast Growth Factor Basic Form MeasurementFLT3 Internal Tandem Duplication+2 more
Northwestern University 44
Not applicableStudy completedNCT02705677
What this trial is testing

Biobanking of Rett Syndrome and Related Disorders

Who this might be right for
Rett SyndromeMECP2 DuplicationCDKL5+1 more
University of Alabama at Birmingham 752
Not applicableEnded earlyNCT06014541
What this trial is testing

Observational Study to Characterize Biomarkers and Disease Progression in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

Who this might be right for
Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Ionis Pharmaceuticals, Inc. 29
Not applicableLooking for participantsNCT06615206
What this trial is testing

A First-in-Human Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of a Novel CRISPR RNA-editing Therapy in Patients with Mecp2 Duplication Syndrome, a Rare Orphan Disease (HERO)

Who this might be right for
MECP2 Duplication Syndrome
HuidaGene Therapeutics Co., Ltd. 6
Not applicableUnknownNCT05049395
What this trial is testing

HFNO Reducing the Incidence of Hypoxia for Hysteroscopy Sedated With Propofol

Who this might be right for
EndometritisTuberculous EndometritisSubseptate Uterus+1 more
RenJi Hospital 960
Testing effectiveness (Phase 2)Study completedNCT02984995
What this trial is testing

Phase 2 Study of Quizartinib in Participants With Acute Myeloid Leukemia (AML) FLT3 Internal Tandem Duplication (FLT3/ITD) Mutation

Who this might be right for
Leukemia, Myeloid, Acute
Daiichi Sankyo Co., Ltd. 37
Testing effectiveness (Phase 2)Ended earlyNCT03635073
What this trial is testing

Soticlestat in Adults and Children With Rare Epilepsies

Who this might be right for
EpilepsyDravet Syndrome (DS)Lennox-Gastaut Syndrome (LGS)
Takeda 156
Testing effectiveness (Phase 2)Ended earlyNCT04240002
What this trial is testing

Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia With FMS-like Tyrosine Kinase 3 (FLT3) Mutation / Internal Tandem Duplication (ITD)
Astellas Pharma Global Development, Inc. 9
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06185400
What this trial is testing

RC48 Combined With EGFR or HER2 TKI for Locally Advanced or Metastatic NSCLC Patients With HER2 Alterations

Who this might be right for
Non Small Cell Lung CancerERBB2 Mutation-Related TumorsERBB2 Gene Duplication+1 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 108
Large-scale testing (Phase 3)Not Yet RecruitingNCT05876832
What this trial is testing

XY0206 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory AML With FLT3-ITD-Mutation (ALIVE)

Who this might be right for
Acute Myeloid Leukemia With FLT3/ITD Mutation
Shijiazhuang Yiling Pharmaceutical Co. Ltd 312
Not applicableStudy completedNCT02853695
What this trial is testing

Implementation of Hysteroscopy in Flanders and the Netherlands

Who this might be right for
HysteroscopyMinimally Invasive Surgical ProceduresPolyp+4 more
University Ghent 249
Not applicableStudy completedNCT04316273
What this trial is testing

Colonic Duplication; Two Cases Report and Review of Literature

Who this might be right for
Colonic Diseases
Assiut University 2
Not applicableLooking for participantsNCT06274164
What this trial is testing

Clinical and Molecular Biomarker Studies in RAI1 (Retinoic Acid-Induced 1) -Related Disorders

Who this might be right for
RAI1 Gene 17P11.2 Deletion+Duplication
Baylor College of Medicine 90
Testing effectiveness (Phase 2)Study completedNCT03836209
What this trial is testing

Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
PrECOG, LLC. 181
Not applicableLooking for participantsNCT06373861
What this trial is testing

Generating Advancements Through Longitudinal Analysis in X and Y Variations (GALAXY)

Who this might be right for
Sex Chromosome Aneuploidy
University of Colorado, Denver 5,000
Not applicableStudy completedNCT00003931
What this trial is testing

Diagnostic Study of Gene Alterations in Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Alliance for Clinical Trials in Oncology 9,769
Not applicableStudy completedNCT05859139
What this trial is testing

Scaling a Decision Aid on Prenatal Screening for Trisomy 21, 18 and 13

Who this might be right for
Decision Aid
CHU de Quebec-Universite Laval 887
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