Early research (Phase 1)Study completedNCT01509846What this trial is testingSafety Study of Inactivated Shigella Whole Cell Vaccine in AdultsWho this might be right forShigellosis PATH 82
Large-scale testing (Phase 3)Active Not RecruitingNCT06838195What this trial is testingClinical Trial of the S. Flexneri-S. Sonnei Bivalent Conjugate VaccineWho this might be right forDysenteryDysentery, Shigella Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd 8,000
Testing effectiveness (Phase 2)Study completedNCT00382304What this trial is testingThe Absorption of GT267-004 in Patients With Clostridium Difficile-Associated DiarrheaWho this might be right forPseudomembranous ColitisClostridium Difficile DiarrheaAntibiotic-Associated Diarrhea Genzyme, a Sanofi Company 24
Testing effectiveness (Phase 2)Study completedNCT00485134What this trial is testingShigella Flexneri 2a Invaplex 50 Vaccine Dose Finding and Assessment of ProtectionWho this might be right forShigellosis U.S. Army Medical Research and Development Command 113
Early research (Phase 1)Study completedNCT02034500What this trial is testingEvaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy AdultsWho this might be right forShigellosis GSK Vaccines Institute For Global Health S.r.l. 52
Post-approval studies (Phase 4)Study completedNCT04192487What this trial is testingEffects of Crofelemer on the Gut Microbiome in Healthy Volunteers and in HIV+ Patients With Non-Infectious DiarrheaWho this might be right forAcquired Immunodeficiency SyndromeHealthy VolunteersHIV/AIDS+2 more Napo Pharmaceuticals, Inc. 17
Not applicableUnknownNCT03778125What this trial is testingMultidrug Resistant Shigella Infection in BangladeshWho this might be right forDiarrheaShigella University of Virginia 2,000
Large-scale testing (Phase 3)Study completedNCT00368316What this trial is testingSafety, Immunogenicity and Efficacy of Shigella Conjugate Vaccines in 1-4 Year Olds in IsraelWho this might be right forShigellosis Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 2,799
Testing effectiveness (Phase 2)Study completedNCT04056117What this trial is testingDetermine If a New Shigella Vaccine is Safe, Induces Immunity and The Best Dose Among Kenyan InfantsWho this might be right forShigellosis LimmaTech Biologics AG 597
Early research (Phase 1)Study completedNCT04992520What this trial is testingControlled Human Infection Model Challenge/RechallengeWho this might be right forShigellosis PATH 46
Testing effectiveness (Phase 2)WithdrawnNCT03038243What this trial is testingSafety, Immunogenicity and Efficacy Study of Inactivated Whole Cell Shigella Flexneri 2a Vaccine With and Without dmLT in AdultsWho this might be right forShigella Sonnei Dysenteries PATH
Early research (Phase 1)Study completedNCT01369927What this trial is testingShigella Sonnel O-SPC/rBRU Conjugate VaccineWho this might be right forImmunogenicityShigellosis Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 60
Early research (Phase 1)Study completedNCT06896136What this trial is testingStudy in Healthy Adults Challenged With Enterotoxigenic E. Coli, of the Safety, Tolerability and Anti-Diarrheal Activity of VENBETA6890, an Orally Administered, Human Monoclonal IgAWho this might be right forDiarrhea Infectious Mark Klempner 36
Early research (Phase 1)Study completedNCT04634513What this trial is testingShigella CVD 31000: Study of Responses With Shigella-ETEC Vaccine Strain CVD 1208S-122Who this might be right forShigella InfectionEnterotoxigenic Escherichia Coli Infection University of Maryland, Baltimore 53
Testing effectiveness (Phase 2)Active Not RecruitingNCT05182749What this trial is testingSafety and Efficacy of the Bacteriophage Preparation, ShigActive™, in a Human Experimental Model of ShigellosisWho this might be right forShigellosis Intralytix, Inc. 52
Not applicableStudy completedNCT05008640What this trial is testingCreation of an E-toileting Log Through Classification of the Physical Properties of Stool and Urine Using TrueLoo™Who this might be right forUrinary Tract InfectionsInfectious DiarrheaClostridium Difficile Infection+2 more Toi Labs, Inc. 143
Testing effectiveness (Phase 2)Study completedNCT06663436What this trial is testingA Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in InfantsWho this might be right forDiarrhoea GlaxoSmithKline 200
Testing effectiveness (Phase 2)Study completedNCT02646371What this trial is testingPhase 2b Challenge Study With the Bioconjugate Vaccine Flexyn2aWho this might be right forShigellosis LimmaTech Biologics AG 67
Not applicableStudy completedNCT02680665What this trial is testingAmeparomo Capsules 250 mg Drug Use InvestigationWho this might be right forIntestinal Amebiasis Pfizer 120
Early research (Phase 1)Study completedNCT02816346What this trial is testingDose-Finding Study of Lyophilized Shigella Sonnei 53G Challenge StrainWho this might be right forHealthy PATH 56