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Results for “Dystrophia Myotonica”

220 trials

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Showing 20 of 220 results

Early research (Phase 1)Ended earlyNCT03429101
What this trial is testing

Poziotinib in Combination With T-DM1 in HER2-Positive Breast Cancer

Who this might be right for
Breast Cancer
Spectrum Pharmaceuticals, Inc 6
Testing effectiveness (Phase 2)Study completedNCT00934856
What this trial is testing

Trastuzumab Emtansine (T-DM1) in Combination With Docetaxel, and Potentially Pertuzumab, in Participants With Advanced Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 98
Not applicableUnknownNCT04698551
What this trial is testing

NIPD on cffDNA for Triplet Repeat Diseases

Who this might be right for
Myotonic Dystrophy 1Huntington DiseaseFragile X Syndrome
University Hospital, Montpellier 36
Large-scale testing (Phase 3)Ended earlyNCT01641939
What this trial is testing

Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer

Who this might be right for
Gastric Cancer
Hoffmann-La Roche 415
Not applicableLooking for participantsNCT07362875
What this trial is testing

Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy

Who this might be right for
Myotonic Dystrophy
Wake Forest University Health Sciences 75
Early research (Phase 1)Study completedNCT03032107
What this trial is testing

Pembrolizumab In Combination With Trastuzumab-DM1

Who this might be right for
Breast Cancer
Dana-Farber Cancer Institute 20
Large-scale testing (Phase 3)Study completedNCT01702571
What this trial is testing

Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer Who Have Received Prior Anti-HER2 And Chemotherapy-based Treatment

Who this might be right for
Breast Cancer
Hoffmann-La Roche 2,185
Large-scale testing (Phase 3)Study completedNCT01421992
What this trial is testing

Methylphenidate in Myotonic Dystrophy Type 1

Who this might be right for
Dystrophia Myotonica 1
Laval University 28
Testing effectiveness (Phase 2)Ended earlyNCT03784599
What this trial is testing

T-DM1 and Osimertinib Combination Treatment to Target HER2 Bypass Track Resistance in EGFR Mutation Positive NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell Lung
The Netherlands Cancer Institute 28
Not applicableLooking for participantsNCT04003363
What this trial is testing

The United Kingdom National Registry for Myotonic Dystrophy

Who this might be right for
Myotonic Dystrophy
Newcastle University 900
Not applicableUnknownNCT05231863
What this trial is testing

Tyrosine Kinase Inhibitors (TKIs) in Trastuzumab Emtansine (T-DM1) Resistant HER2-positive Metastatic Breast Cancer: A Real-world Study

Who this might be right for
Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 100
Large-scale testing (Phase 3)Enrolling By InvitationNCT06549400
What this trial is testing

An Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Once Daily Mexiletine PR in Patients With Myotonic Dystrophy Type 1 and Type 2 Who Have Completed MEX-DM-302 Study.

Who this might be right for
Myotonic Dystrophy
Lupin Ltd. 176
Large-scale testing (Phase 3)Looking for participantsNCT07486934
What this trial is testing

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy Type 1 (DM1)DM1Myotonic Dystrophy+2 more
Dyne Therapeutics 150
Not applicableUnknownNCT02708784
What this trial is testing

An MRI Study on Muscular Diseases -Pompe Disease and Dystrophia Myotonica-

Who this might be right for
Glycogen Storage Disease Type 2Dystrophia Myotonica
University of Aarhus 60
Not applicableLooking for participantsNCT02398786
What this trial is testing

Myotonic Dystrophy Family Registry

Who this might be right for
Myotonic DystrophyCongenital Myotonic DystrophyMyotonic Dystrophy 1+13 more
Myotonic Dystrophy Foundation 3,500
Testing effectiveness (Phase 2)Study completedNCT01406873
What this trial is testing

Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy
University of Rochester 42
Large-scale testing (Phase 3)Study completedNCT03692312
What this trial is testing

Efficacy and Safety of Tideglusib in Congenital Myotonic Dystrophy

Who this might be right for
Congenital Myotonic Dystrophy
AMO Pharma Limited 56
Not applicableStudy completedNCT05400629
What this trial is testing

Effects of a 12-week Strength Training Program in Women With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy 1
Université de Sherbrooke 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT02326974
What this trial is testing

T-DM1+Pertuzumab in Pre-OP Early-Stage HER2+ BRCA

Who this might be right for
HER-2 Positive Breast CancerBreast CancerStage II Breast Cancer+1 more
Dana-Farber Cancer Institute 164
Testing effectiveness (Phase 2)WithdrawnNCT03203616
What this trial is testing

Kadcyla In pAtients With bRAin Metastasis

Who this might be right for
Metastatic HER2-positive Breast Cancer With Brain Metastasis
Jules Bordet Institute
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