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Results for “EGFR ADC”

51 trials

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Showing 20 of 51 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07649980
What this trial is testing

Becotatug Vedotin Plus Pucotenlimab for Advanced Biliary Tract Cancer, Phase II

Who this might be right for
Biliary Tract Cancer (BTC)EGFR-positive Advanced Biliary Tract Carcinoma
HuiKai Li 30
Testing effectiveness (Phase 2)Study completedNCT06188559
What this trial is testing

BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive or HER2-low Unresectable or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Eisai Inc. 56
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07766889
What this trial is testing

Neoadjuvant Presurgical Becotatug Vedotin (MRG003) Plus Pucotenlimab (HX008) in Oral Cavity Squamous Cell Carcinoma

Who this might be right for
Oral Squamous Cell CarcinomaHead and Neck CancerLocally Advanced Head and Neck Cancer+1 more
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Looking for participantsNCT07665190
What this trial is testing

Neoadjuvant EGFR-ADC Combined With Anti-PD-1 Monoclonal Antibody in Resectable Locally Advanced Hypopharyngeal Squamous Cell Carcinoma

Who this might be right for
Hypopharyngeal Squamous Cell Carcinoma
Tianjin Medical University Cancer Institute and Hospital 52
Early research (Phase 1)Not Yet RecruitingNCT07697040
What this trial is testing

Becotatug Vedotin Plus Cisplatin and Radiotherapy in LA-ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
Hebei Medical University Fourth Hospital 12
Large-scale testing (Phase 3)Not Yet RecruitingNCT07598318
What this trial is testing

Study of Becotatug Vedotin Added to Standard Treatment for Advanced Bile Duct Cancer With EGFR Mutations

Who this might be right for
Cholangiocarcinoma
Sir Run Run Shaw Hospital 164
Testing effectiveness (Phase 2)Looking for participantsNCT07548060
What this trial is testing

A Phase II Study of Sacituzumab Tirumotecan in Combination With Furmonertinib in Patients With Non-squamous Non-Small Cell Lung Cancer Who Have Progressed After EGFR-TKI and Platinum-Based Chemotherapy

Who this might be right for
NSCLC Stage IVEGFR Gene Mutation
Tianjin Medical University Cancer Institute and Hospital 25
Testing effectiveness (Phase 2)Looking for participantsNCT07518979
What this trial is testing

EGFR-ADC (Becotatug Vedotin) Combined With PD-1 Inhibitor (Pucotenlimab) in Neoadjuvant Treatment of Advanced Penile Cancer

Who this might be right for
Penile Cancer
Jiyan Liu 60
Early research (Phase 1)Looking for participantsNCT05142189
What this trial is testing

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
BioNTech SE 320
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07514533
What this trial is testing

The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma
Sir Run Run Shaw Hospital 60
Testing effectiveness (Phase 2)Study completedNCT04681131
What this trial is testing

CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC

Who this might be right for
Non-Small-Cell Lung Cancer
BioAtla, Inc. 85
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07193160
What this trial is testing

Sacituzumab Tirumotecan in Combination With Furmonertinib as Second-line Treatment for EGFR-mutant Advanced or Metastatic NSCLC After Failure of First-line Third-generation EGFR-TKI Therapy

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
Fudan University 45
Early research (Phase 1)Looking for participantsNCT07444814
What this trial is testing

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

Who this might be right for
Endometrial CancerOvarian CancerOvarian Cancer Metastatic+4 more
Whitehawk Therapeutics, Inc. 226
Testing effectiveness (Phase 2)Study completedNCT04838964
What this trial is testing

MRG003 in the Treatment of EGFR-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer

Who this might be right for
Advanced or Metastatic Biliary Tract Cancer
Lepu Biopharma Co., Ltd. 15
Large-scale testing (Phase 3)Active Not RecruitingNCT06074588
What this trial is testing

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Merck Sharp & Dohme LLC 556
Large-scale testing (Phase 3)Looking for participantsNCT07459751
What this trial is testing

A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer

Who this might be right for
Advanced or Metastatic Squamous Non-Small Cell Lung Cancer
Shanghai Henlius Biotech 706
Early research (Phase 1)Study completedNCT03368196
What this trial is testing

DS-8201a in Patients With Cancer That Tests Positive for Human Epidermal Growth Factor Receptor 2 (HER2) Protein

Who this might be right for
Adenocarcinoma, GastricNeoplasm, Breast
Daiichi Sankyo Taiwan Ltd., a Daiichi Sankyo Company 12
Early research (Phase 1)Looking for participantsNCT06621563
What this trial is testing

Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors

Who this might be right for
Solid TumorsNon-Small Cell Lung CancerColorectal Cancer
Hansoh BioMedical R&D Company 780
Early research (Phase 1)Looking for participantsNCT07539285
What this trial is testing

HDM2024 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 63
Large-scale testing (Phase 3)Looking for participantsNCT06340568
What this trial is testing

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Who this might be right for
Endometrial Cancer
BioNTech SE 480
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