Not applicableUnknownNCT03764917What this trial is testingNGS Combined With RNAseq on Tumor Immune Escape in NSCLCWho this might be right forNon-small Cell Lung Cancer Shanghai Pulmonary Hospital, Shanghai, China 100
Early research (Phase 1)Not Yet RecruitingNCT06067776What this trial is testingOsimertinib, Cetuximab, and Tucatinib for the Treatment of EGFR-Mutant Stage IV or Recurrent Non-small Lung Cell CancerWho this might be right forMetastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8 Jonathan Riess 36
Not applicableStudy completedNCT07267247What this trial is testingCancer Therapy-Related Cardiac Dysfunction Associated With EGFR-TKIs in Advanced EGFR-mutant Non-small Cell Lung CancerWho this might be right forNon-Small Cell Lung Cancer (MeSH Term: Carcinoma, Non-Small-Cell Lung)Drug-Related Side Effects and Adverse Reactions (MeSH Term)Egfr Tyrosine Kinase Inhibitor+1 more Taichung Veterans General Hospital 100
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06250777What this trial is testingEfficacy and Safety of T-DXd in HER2-mutant Advanced Lung Cancer Patients With Asymptomatic Brain MetastasesWho this might be right forNon Small Cell Lung Cancer Yonsei University 27
Testing effectiveness (Phase 2)Study completedNCT05017025What this trial is testingAurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung CancerWho this might be right forAdvanced Lung Non-Squamous Non-Small Cell CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+6 more M.D. Anderson Cancer Center 32
Testing effectiveness (Phase 2)Ended earlyNCT06186076What this trial is testingInvestigate Safety, Tolerability, PK and Anti-tumor Activity of TRX-221 in EGFRm NSCLC PatientsWho this might be right forCarcinoma, Non-Small-Cell LungEGFR Mutant Advanced Non-Small Cell Lung Cancer Therapex Co., Ltd 19
Early research (Phase 1)UnknownNCT02321293What this trial is testingProspective Cohort Trial of Curcumin Plus Tyrosine Kinase Inhibitors (TKI) for EGFR -Mutant Advanced NSCLCWho this might be right forLung Cancer Lady Davis Institute 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03667820What this trial is testingStudy of Osimertinib and Stereotactic Ablative Radiation (SABR) in EGFR Mutant NSCLCWho this might be right forNon-small Cell Lung Cancer (NSCLC) University of Texas Southwestern Medical Center 41
Early research (Phase 1)Study completedNCT05926180What this trial is testingAssessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients with EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)Who this might be right forNon-small Cell Lung Cancer Dizal Pharmaceuticals 25
Large-scale testing (Phase 3)Ended earlyNCT02322281What this trial is testingTIGER-3: Open Label, Multicenter Study of Rociletinib (CO-1686) Mono Therapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR NSCLC Who Have Failed at Least One Previous EGFR-Directed TKI and Platinum-doublet ChemotherapyWho this might be right forNon-small Cell Lung Cancer Clovis Oncology, Inc. 149
Early research (Phase 1)Looking for participantsNCT05142189What this trial is testingClinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung CancerWho this might be right forNon-Small Cell Lung Cancer BioNTech SE 320
Testing effectiveness (Phase 2)UnknownNCT00339586What this trial is testingFirst-Line EGFR-1 Tyrosine Kinase Inhibition in Patients With NSCLC With Mutant EGFR GeneWho this might be right forLung NeoplasmsNon-Small Cell Lung CancerAdenocarcinoma, Bronchiolo-Alveolar Universitair Ziekenhuis Brussel 40
Not applicableStudy completedNCT03761901What this trial is testingStudy to Describe Treatment Patterns and Outcomes in EGFRm NSCLC Patients in BelgiumWho this might be right forCarcinoma, Non-Small-Cell Lung AstraZeneca 141
Testing effectiveness (Phase 2)UnknownNCT05255406What this trial is testingEfficacy and Safety of Furmonertinib in EGFR-Mutant, PD-L1+ Patients With Locally Advanced or Metastatic NSCLC (FUTURE)Who this might be right forNon-Small-Cell Lung Cancer Fudan University 62
Testing effectiveness (Phase 2)Active Not RecruitingNCT05920135What this trial is testingFirst-in-Human Study of BBT-207 in Advanced Non-Small Cell Lung Cancer Harboring EGFR Mutation After Treatment With EGFR TKIWho this might be right forEGFR Mutant Advanced Non-Small Cell Lung Cancer Bridge Biotherapeutics, Inc. 24
Testing effectiveness (Phase 2)UnknownNCT06334757What this trial is testingSerplulimab Plus Bevacizumab and Chemotherapy for EGFR-mutant Metastatic NSCLC Patients After EGFR-TKI Treatment FailureWho this might be right forNon-Squamous Non-Small Cell Lung Cancer Henan Cancer Hospital 46
Testing effectiveness (Phase 2)Looking for participantsNCT05642572What this trial is testingComparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)Who this might be right forRecurrent Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8 SWOG Cancer Research Network 66
Not applicableNot Yet RecruitingNCT07714304What this trial is testingJS212 in Combination With JS111 as First-Line Treatment in EGFR-Mutant Advanced NSCLCWho this might be right forNSCLC Harboring EGFR Mutations Huan Zhou 20
Early research (Phase 1)Ended earlyNCT03255083What this trial is testingDS-1205c With Osimertinib for Metastatic or Unresectable Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung CancerWho this might be right forNon-small Cell Lung Cancer (NSCLC) Daiichi Sankyo 13
Testing effectiveness (Phase 2)Looking for participantsNCT07323056What this trial is testingNeoadjuvant Sacituzumab Tirumotecan and Limertinib for Potentially Resectable Stage Ⅲ EGFR-mutant Non-small Cell Lung CancerWho this might be right forEGFR-mutant Non-small Cell Lung CancerPotentially Resectable Shanghai Pulmonary Hospital, Shanghai, China 36