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Results for “EGFR Positive Solid Tumors”

46 trials

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Showing 20 of 46 results

Early research (Phase 1)Study completedNCT01482377
What this trial is testing

RO5479599 Alone or in Combination With Cetuximab or Erlotinib in Participants With Metastatic and/or Locally Advanced Malignant Human Epidermal Growth Factor Receptor (HER3) Expressing Solid Tumors of Epithelial Cell Origin

Who this might be right for
Neoplasms
Hoffmann-La Roche 145
Very early researchLooking for participantsNCT05341492
What this trial is testing

EGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer

Who this might be right for
EGFR/ B7H3-positive Advanced Lung CancerEGFR/ B7H3-positive Advanced Triple-negative Breast Cancer
Second Affiliated Hospital of Guangzhou Medical University 30
Early research (Phase 1)Study completedNCT02345174
What this trial is testing

Immuno Positron Emission Tomography Study of GSK2849330 in Subjects With Human Epidermal Growth Factor Receptor 3-Positive Solid Tumors

Who this might be right for
CancerNeoplasms
GlaxoSmithKline 6
Early research (Phase 1)UnknownNCT04976218
What this trial is testing

TGFβR-KO CAR-EGFR T Cells in Previously Treated Advanced EGFR-positive Solid Tumors

Who this might be right for
Solid Tumor, AdultEGFR Overexpression
Chinese PLA General Hospital 30
Early research (Phase 1)Study completedNCT02965885
What this trial is testing

TAS-116 in Patients With Solid Tumors

Who this might be right for
Advanced Solid Tumors
Taiho Oncology, Inc. 31
Early research (Phase 1)Looking for participantsNCT06253871
What this trial is testing

A Phase 1/1b Study of IAM1363 in HER2 Cancers

Who this might be right for
HER2 Mutation-Related TumorsHER2HER2-positive Breast Cancer+10 more
Iambic Therapeutics, Inc 243
Testing effectiveness (Phase 2)WithdrawnNCT04464967
What this trial is testing

Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers

Who this might be right for
Advanced Solid TumorMetastatic CancerHER2-positive Breast Cancer+14 more
NKGen Biotech, Inc.
Early research (Phase 1)Ended earlyNCT03284723
What this trial is testing

PF-06804103 Dose Escalation in HER2 Positive and Negative (Negative Only in Part 2) Solid Tumors

Who this might be right for
Breast Neoplasms
Pfizer 95
Testing effectiveness (Phase 2)UnknownNCT03182816
What this trial is testing

CTLA-4 and PD-1 Antibodies Expressing EGFR-CAR-T Cells for EGFR Positive Advanced Solid Tumor

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Research Institute 40
Early research (Phase 1)Looking for participantsNCT06960395
What this trial is testing

Safety and Preliminary Efficacy of VIR-5525 and VIR-5525 + Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor MalignanciesEGFR Positive Solid TumorsEGFR
Vir Biotechnology, Inc. 450
Testing effectiveness (Phase 2)Looking for participantsNCT03175224
What this trial is testing

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

Who this might be right for
Solid TumorsAdvanced CancerRenal Cancer+15 more
Apollomics Inc. 497
Not applicableNot Yet RecruitingNCT07122882
What this trial is testing

Integrated Genomics in Oncogene-driven NSCLC With Acquired Resistance

Who this might be right for
Oncogene-addicted Non Small Cell Lung CancerEGFR MutationALK Fusion-positive Solid or CNS Tumors+10 more
Chang Gung Memorial Hospital 40
Early research (Phase 1)Looking for participantsNCT03740256
What this trial is testing

Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

Who this might be right for
Bladder CancerHead and Neck Squamous Cell CarcinomaCancer of the Salivary Gland+7 more
Baylor College of Medicine 45
Very early researchLooking for participantsNCT06824155
What this trial is testing

HEAT Trial (HER2 Antibody Therapy With Lutetium-177)

Who this might be right for
HER2 Gene MutationAdvanced Solid Tumors
Radiopharm Theranostics, Ltd 30
Testing effectiveness (Phase 2)Looking for participantsNCT05985655
What this trial is testing

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)Pancreatic AdenocarcinomaNon-small Cell Lung Cancer (NSCLC)+3 more
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc. 230
Early research (Phase 1)Study completedNCT03841110
What this trial is testing

FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsLymphomaGastric Cancer+15 more
Fate Therapeutics 37
Testing effectiveness (Phase 2)UnknownNCT02873390
What this trial is testing

PD-1 Antibody Expressing CAR-T Cells for EGFR Family Member Positive Advanced Solid Tumor

Who this might be right for
PD-1 AntibodyCAR-T CellsAdvanced Malignancies
Ningbo Cancer Hospital 20
Early research (Phase 1)WithdrawnNCT06341647
What this trial is testing

Phase 1 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-201

Who this might be right for
Breast CancerGastric CancerGastroesophageal Junction Adenocarcinoma
GC Cell Corporation
Testing effectiveness (Phase 2)Ended earlyNCT01953926
What this trial is testing

Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations

Who this might be right for
Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
Puma Biotechnology, Inc. 582
Testing effectiveness (Phase 2)UnknownNCT05688605
What this trial is testing

MRG003 in the Treatment of Patients With EGFR-positive Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumors
Shanghai Miracogen Inc. 18
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