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Results for “EGFR Positive Solid Tumors”

50 trials

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Showing 20 of 50 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05262400
What this trial is testing

Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors

Who this might be right for
Breast CancerSolid Tumors
Pfizer 235
Testing effectiveness (Phase 2)Active Not RecruitingNCT05593094
What this trial is testing

Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsHER2-positive Breast Cancer
Hoffmann-La Roche 210
Testing effectiveness (Phase 2)UnknownNCT01869166
What this trial is testing

Treatment of Chemotherapy Refractory EGFR(Epidermal Growth Factor Receptor) Positive Advanced Solid Tumors (CART-EGFR)

Who this might be right for
Advanced EGFR-positive Solid Tumors
Chinese PLA General Hospital 60
Testing effectiveness (Phase 2)Ended earlyNCT04172597
What this trial is testing

Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies

Who this might be right for
Breast CancerColorectal CancerSolid Tumor+1 more
Spectrum Pharmaceuticals, Inc 1
Early research (Phase 1)UnknownNCT04976218
What this trial is testing

TGFβR-KO CAR-EGFR T Cells in Previously Treated Advanced EGFR-positive Solid Tumors

Who this might be right for
Solid Tumor, AdultEGFR Overexpression
Chinese PLA General Hospital 30
Testing effectiveness (Phase 2)Ended earlyNCT01953926
What this trial is testing

Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations

Who this might be right for
Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
Puma Biotechnology, Inc. 582
Early research (Phase 1)Study completedNCT02345174
What this trial is testing

Immuno Positron Emission Tomography Study of GSK2849330 in Subjects With Human Epidermal Growth Factor Receptor 3-Positive Solid Tumors

Who this might be right for
CancerNeoplasms
GlaxoSmithKline 6
Testing effectiveness (Phase 2)Looking for participantsNCT06947811
What this trial is testing

Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS Mutations

Who this might be right for
EGFR Tyrosine Kinase Inhibitors Plus Cyclin-dependent Kinase 4/6 Inhibitor
Sun Yat-sen University 71
Not applicableEnded earlyNCT04106167
What this trial is testing

Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy

Who this might be right for
Advanced Solid TumorLymphomaGastric Cancer+15 more
Fate Therapeutics 20
Testing effectiveness (Phase 2)Looking for participantsNCT03175224
What this trial is testing

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

Who this might be right for
Solid TumorsAdvanced CancerRenal Cancer+15 more
Apollomics Inc. 497
Testing effectiveness (Phase 2)UnknownNCT02873390
What this trial is testing

PD-1 Antibody Expressing CAR-T Cells for EGFR Family Member Positive Advanced Solid Tumor

Who this might be right for
PD-1 AntibodyCAR-T CellsAdvanced Malignancies
Ningbo Cancer Hospital 20
Early research (Phase 1)WithdrawnNCT06341647
What this trial is testing

Phase 1 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-201

Who this might be right for
Breast CancerGastric CancerGastroesophageal Junction Adenocarcinoma
GC Cell Corporation
Early research (Phase 1)Looking for participantsNCT04872166
What this trial is testing

BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

Who this might be right for
Advanced Solid TumorMetastatic Breast Cancer
Edgewood Oncology Inc. 112
Early research (Phase 1)Active Not RecruitingNCT06299124
What this trial is testing

A Phase I Study of RGT-419B in Patients With HR-Positive, HER2-Negative Advanced Breast Cancer or Other Solid Tumors

Who this might be right for
Breast CancerAdvanced Solid Tumor
Regor Pharmaceuticals Inc. 40
Not applicableNot Yet RecruitingNCT07191405
What this trial is testing

Clinical Study of Chemotherapy and Immunotherapy Combined With Lactobacillus Johnsonii in Patients With Multiple Irresectable Solid Tumors

Who this might be right for
ImmunotherapyChemotherapy
Second Affiliated Hospital, Zhejiang University, School of Medicine 156
Early research (Phase 1)WithdrawnNCT05905341
What this trial is testing

Study of PF-07224826, as a Single Agent or in Combination With Endocrine Therapy in Participants With Breast Cancer and Other Advanced Solid Tumors.

Who this might be right for
Breast CancerOvarian CancerLiposarcoma+3 more
Pfizer
Very early researchLooking for participantsNCT05341492
What this trial is testing

EGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer

Who this might be right for
EGFR/ B7H3-positive Advanced Lung CancerEGFR/ B7H3-positive Advanced Triple-negative Breast Cancer
Second Affiliated Hospital of Guangzhou Medical University 30
Early research (Phase 1)Looking for participantsNCT06414733
What this trial is testing

HER-2 B Cell Peptide Vaccine

Who this might be right for
Metastatic Breast CancerHER2-positive Breast CancerEGFR Overexpression+2 more
Pravin T.P Kaumaya 42
Testing effectiveness (Phase 2)UnknownNCT03182816
What this trial is testing

CTLA-4 and PD-1 Antibodies Expressing EGFR-CAR-T Cells for EGFR Positive Advanced Solid Tumor

Who this might be right for
Advanced Solid Tumor
Shanghai Cell Therapy Research Institute 40
Early research (Phase 1)Study completedNCT01222637
What this trial is testing

CetuGEX™: Phase 1 Study in Cancer Patients

Who this might be right for
Solid Tumors
Glycotope GmbH 41
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