Testing effectiveness (Phase 2)WithdrawnNCT06227897What this trial is testingAumolertinib in EGFR-Mutant Resected Stage IB-IIIA NSCLC (AERESA).Who this might be right forLung Cancer Sun Yat-sen University
Early research (Phase 1)WithdrawnNCT01836341What this trial is testingAfatinib In Combination With Cisplatin Or Carboplatin + Pemetrexed In Patients With EGFR-Mutant Lung Cancers Undergoing Definitive ChemoradiationWho this might be right forNon-small Cell Lung Cancer Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07197008What this trial is testingSacituzumab Tirumotecan (Sac-TMT) Plus Bevacizumab in 3rd Generation EGFR-TKI Treated Advanced EGFR-mutant Nonsquamous NSCLC With Brain MetastasisWho this might be right forLung Cancer Li-kun Chen 50
Testing effectiveness (Phase 2)Looking for participantsNCT06863506What this trial is testingPhase II Clinical Study of Befotertinib in EGFR Non-classical Mutant NSCLCWho this might be right forNSCLC (Non-small Cell Lung Cancer) Second Affiliated Hospital, Zhejiang University, School of Medicine 78
Not applicableLooking for participantsNCT07143045What this trial is testingA Prospective Cohort Study of Zorifertinib as a First-line Treatment in Patients With Epidermal Growth Factor Receptor-mutant Advanced Non-small Cell Lung Cancer With Central Nervous System (CNS) MetastasesWho this might be right forEGFR Mutant Advanced Non-small Cell Lung CancerCentral Nervous System (CNS) Metastases Alpha Biopharma (Jiangsu) Co., Ltd. 800
Not applicableUnknownNCT02851329What this trial is testingTherapeutic Resistance Prediction of Tyrosine Kinase InhibitorsWho this might be right forNon-small Cell Lung Cancer Chinese Academy of Sciences 500
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07413952What this trial is testingLimertinib Plus Radiotherapy for EGFR-Mutant NSCLC With Brain MetastasesWho this might be right forNSCLC The First Affiliated Hospital of Guangzhou Medical University 45
Not applicableUnknownNCT04304638What this trial is testingReal-world Treatment Patterns and Clinical Outcomes in EGFR-mutant Unresectable Locally Advanced NSCLCWho this might be right forNon Small Cell Lung CancerStage III Non-small-cell Lung CancerEGFR Mutation-Related Tumors Chinese Academy of Medical Sciences 450
Testing effectiveness (Phase 2)Looking for participantsNCT06355609What this trial is testingSunvozertinib Plus Anlotinib as 1L Treatment in EGFR Mutant Advanced NSCLC-RWWho this might be right forNon-small Cell Lung Cancer Hunan Province Tumor Hospital 100
Testing effectiveness (Phase 2)Looking for participantsNCT06775743What this trial is testingORIENT-31 Regimen in Combination With SBRT for EGFR-mutant Metastatic NSCLC After First-line Third-generation EGFR-TKIsWho this might be right forNSCLC (Advanced Non-small Cell Lung Cancer)EGFR Mutation Positive Advanced Non Small Cell Lung Cancer Fudan University 53
Not applicableUnknownNCT03916913What this trial is testingTKI Followed by Thoracic Radiotherapy for Stage IV EGFR Mutant NSCLCWho this might be right forNon-Small Cell Lung Cancer Metastatic Chinese Academy of Medical Sciences 85
Testing effectiveness (Phase 2)Looking for participantsNCT04410796What this trial is testingOsimertinib Alone or With Chemotherapy for EGFR-Mutant Lung CancersWho this might be right forMetastatic Non-small Cell Lung Cancer Memorial Sloan Kettering Cancer Center 571
Not applicableUnknownNCT04944069What this trial is testingAlmonertinib With Bevacizumab for EGFR-Mutant NSCLC Patients With Leptomeningeal MetastasisWho this might be right forNSCLCLeptomeningeal MetastasisEGFR Activating Mutation Second Affiliated Hospital of Nanchang University 69
Testing effectiveness (Phase 2)UnknownNCT05244213What this trial is testingNeoadjuvant Immunotherapy in EGFR-mutant Localized NSCLCWho this might be right forNon-small Cell Lung CancerEGFR Activating Mutation Guangdong Provincial People's Hospital 35
Testing effectiveness (Phase 2)Looking for participantsNCT07742332What this trial is testingTargeted Induction Therapy for Stage III Unresectable EGFR Mutant Positive NSCLCWho this might be right forEGFRNSCLC (Non-small Cell Lung Cancer)Locally Advanced Non-Small Cell Lung Cancer+2 more Peng Zhang 160
Testing effectiveness (Phase 2)Ended earlyNCT01189435What this trial is testingErlotinib Re-Challenge for Recurrent EGFR-mutant Lung Cancer in Patients Who Previously Received Adjuvant Erlotinib or GefitinibWho this might be right forLung Cancer Memorial Sloan Kettering Cancer Center 2
Early research (Phase 1)UnknownNCT02151721What this trial is testingPhase I of Vorinostat-Iressa Combined Therapy on Resistance by BIM Polymorphysim in EGFR Mutant Lung CancerWho this might be right forNon-Small-Cell Lung Carcinoma Kanazawa University 12
Testing effectiveness (Phase 2)Looking for participantsNCT06652048What this trial is testingHigh-dose Furmonertinib or Combined With Chemotherapy in EGFR-mutant Advanced NSCLC After Disease Progression on Third-generation EGFR-TKIWho this might be right forNon-Small Cell Lung Cancer Jialei Wang 60
Large-scale testing (Phase 3)Ended earlyNCT02322281What this trial is testingTIGER-3: Open Label, Multicenter Study of Rociletinib (CO-1686) Mono Therapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR NSCLC Who Have Failed at Least One Previous EGFR-Directed TKI and Platinum-doublet ChemotherapyWho this might be right forNon-small Cell Lung Cancer Clovis Oncology, Inc. 149
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07177092What this trial is testingPrimary Tumor Resection Plus Osimertinib in Advanced EGFR-mutant Non-small Cell Lung CancerWho this might be right forNon-Small Cell Lung CancerEGFR Jianxing He 118