Testing effectiveness (Phase 2)Active Not RecruitingNCT03778229What this trial is testingOsimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior OsimertinibWho this might be right forCarcinoma AstraZeneca 367
Not applicableEnded earlyNCT03053297What this trial is testingObservational Study of Patients With Locally Advanced or Metastatic NSCLC (Non-Small Cell Lung Cancer)Who this might be right forCarcinoma, Non-Small-Cell Lung AstraZeneca 89
Early research (Phase 1)Active Not RecruitingNCT06147037What this trial is testingA Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid TumoursWho this might be right forAdvanced Solid TumorMetastatic Colorectal CarcinomaHead and Neck Squamous Cell Carcinoma+4 more AstraZeneca 13
Large-scale testing (Phase 3)Not Yet RecruitingNCT06970782What this trial is testingVebreltinib Plus PLB1004 Versus Platinum-based Doublet Chemotherapy in Patients With EGFRm, MET+, Locally Advanced or Metastatic NSCLC Following EGFR-TKI FailureWho this might be right forNon-Small-Cell Lung Cancer Avistone Biotechnology Co., Ltd. 278
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06319950What this trial is testingHigh-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain MetastasesWho this might be right forLung Cancer, Nonsmall Cell Taizhou Hospital 255
Not applicableStudy completedNCT06039683What this trial is testingA Multicountry, Multicentre, Non-interventional, Retrospective Study to Determine Real-world Treatment Patterns and Associated Outcomes After First Line Osimertinib in Patients With Advanced and Metastatic NSCLC EGFRm in the GCC RegionWho this might be right forCarcinoma, Non-Small-Cell Lung AstraZeneca 54
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07486648What this trial is testingOsimertinib Plus Capivasertib in NSCLC With PIK3CA/AKT1/PTEN Alterations Following Prior 1L OsimertinibWho this might be right forLung Cancer (NSCLC)Lung Cancer (Non-Small Cell)Advanced Non-small-cell Lung Cancer Shanxi Province Cancer Hospital 53
Post-approval studies (Phase 4)Study completedNCT05219162What this trial is testingReal-World Study on Gene Profile in Patients With Advanced NSCLC Who Progressed on First-Line Osimertinib Therapy(GPS).Who this might be right forAdvanced NSCLC AstraZeneca 182