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Results for “EGFRvIII”

33 trials

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Showing 20 of 33 results

Testing effectiveness (Phase 2)Looking for participantsNCT07326566
What this trial is testing

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Who this might be right for
Glioblastoma (GBM)Newly Diagnosed GlioblastomaGBM+4 more
Black Diamond Therapeutics, Inc. 162
Early research (Phase 1)Study completedNCT02378532
What this trial is testing

The Addition of Chloroquine to Chemoradiation for Glioblastoma

Who this might be right for
Glioblastoma Multiforme
Maastricht Radiation Oncology 13
Early research (Phase 1)Ended earlyNCT02209376
What this trial is testing

Autologous T Cells Redirected to EGFRVIII-With a Chimeric Antigen Receptor in Patients With EGFRVIII+ Glioblastoma

Who this might be right for
Patients With Residual or Reccurent EGFRvIII+ Glioma
University of Pennsylvania 11
Early research (Phase 1)Ended earlyNCT03296696
What this trial is testing

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Who this might be right for
Glioblastoma or Malignant Glioma
Amgen 30
Early research (Phase 1)UnknownNCT02844062
What this trial is testing

Pilot Study of Autologous Anti-EGFRvIII CAR T Cells in Recurrent Glioblastoma Multiforme

Who this might be right for
Glioblastoma Multiforme
Beijing Sanbo Brain Hospital 20
Testing effectiveness (Phase 2)Study completedNCT00458601
What this trial is testing

Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma Multiforme

Who this might be right for
Malignant Glioma
Celldex Therapeutics 82
Early research (Phase 1)Looking for participantsNCT07551336
What this trial is testing

Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma

Who this might be right for
Malignant GliomaHigh-Grade GliomasGlioblastoma+2 more
Beijing Biotech 36
Testing effectiveness (Phase 2)Study completedNCT00643097
What this trial is testing

Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Who this might be right for
Malignant Neoplasms of Brain
John Sampson 40
Testing effectiveness (Phase 2)Looking for participantsNCT02861898
What this trial is testing

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Who this might be right for
GlioblastomaBrain CancerBrain Neoplasm+4 more
Northwell Health 33
Early research (Phase 1)Ended earlyNCT03283631
What this trial is testing

Intracerebral EGFR-vIII CAR-T Cells for Recurrent GBM

Who this might be right for
Recurrent GlioblastomaRecurrent Gliosarcoma
Gary Archer Ph.D. 2
Early research (Phase 1)Looking for participantsNCT06186401
What this trial is testing

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

Who this might be right for
EGFR Gene MutationGlioblastomaMGMT-Unmethylated Glioblastoma+1 more
Hideho Okada, MD, PhD 20
Not applicableStudy completedNCT02666248
What this trial is testing

Long-term Follow-up of Subjects Exposed to Lentiviral-based CART-EGFRvIII Gene-modified Cellular Therapy Products in Cancer Studies

Who this might be right for
Subjects Entering Into This Protocol Will be Followed for up to 15 Years After Initial CART-EGFRvIII Infusion
University of Pennsylvania 3
Early research (Phase 1)Looking for participantsNCT07579208
What this trial is testing

A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma

Who this might be right for
Phase 1NK CellIL13Ra+4 more
M.D. Anderson Cancer Center 36
Testing effectiveness (Phase 2)Looking for participantsNCT07523529
What this trial is testing

Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors

Who this might be right for
Advanced UnresectableMetastatic
Beijing Biotech 72
Early research (Phase 1)Study completedNCT03726515
What this trial is testing

CART-EGFRvIII + Pembrolizumab in GBM

Who this might be right for
Glioblastoma
University of Pennsylvania 7
Early research (Phase 1)Ended earlyNCT00023634
What this trial is testing

S0114 Vaccine Therapy in Treating Patients With Gastric, Prostate, or Ovarian Cancer

Who this might be right for
Brain TumorsGastric CancerOvarian Cancer+1 more
SWOG Cancer Research Network 14
Very early researchUnknownNCT05802693
What this trial is testing

Evaluate the Safety, Tolerance and Initial Efficacy of EGFRvIII CAR-T on Glioblastoma

Who this might be right for
Recurrent Glioblastoma
Beijing Tsinghua Chang Gung Hospital 22
Early research (Phase 1)Looking for participantsNCT04903795
What this trial is testing

BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma

Who this might be right for
Newly Diagnosed GlioblastomaRecurrent Glioblastoma
Mustafa Khasraw, MBChB, MD, FRCP, FRACP 18
Early research (Phase 1)Ended earlyNCT02664363
What this trial is testing

EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant Glioma

Who this might be right for
GlioblastomaGliosarcoma
Daniel Landi 3
Early research (Phase 1)Study completedNCT01238237
What this trial is testing

Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA

Who this might be right for
Glioblastoma Multiforme (GBM)ANAPLASTIC ASTROCYTOMA (AOA)GBM+1 more
Northwell Health 15
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