Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Early and Locally Advanced Breast Cancer”

92 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 92 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07107217
What this trial is testing

Camrelizumab in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-negative Breast Cancer

Who this might be right for
Breast Cancer
Blokhin's Russian Cancer Research Center 40
Testing effectiveness (Phase 2)Study completedNCT03112590
What this trial is testing

Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer

Who this might be right for
Breast CancerBreast Cancer, MaleBreast Cancer Female+1 more
H. Lee Moffitt Cancer Center and Research Institute 51
Not applicableLooking for participantsNCT05957068
What this trial is testing

Breast Cancer Exercise Intervention Study

Who this might be right for
Early-stage Breast CancerLocally Advanced Breast Cancer
National Cancer Centre, Singapore 2,156
Testing effectiveness (Phase 2)Study completedNCT00978770
What this trial is testing

MRI in Predicting Early Response to Chemotherapy in Patients With Locally Advanced Breast Cancer

Who this might be right for
Breast Cancer
Cancer Clinical Trials Unit, Scotland 50
Testing effectiveness (Phase 2)UnknownNCT05726175
What this trial is testing

Disitamab Vedotin(RC48) Combined With Penpulimab(AK105) for Neoadjuvant Treatment of HER2-low Breast Cancer

Who this might be right for
Breast Cancer
West China Hospital 20
Not applicableAvailableNCT07643831
What this trial is testing

Expanded Access Program to Provide Giredestrant to Participants With ER+, HER2- Early or Locally Advanced/Metastatic Breast Cancer

Who this might be right for
ER+/HER2- Early or Locally Advanced/Metastatic Breast Cancer
Genentech, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT04481932
What this trial is testing

Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

Who this might be right for
HER2-positive Breast Cancer
Peking University 104
Not applicableStudy completedNCT05217381
What this trial is testing

Real-World Data of Clinicopathological Characteristics and Management of Breast Cancer Patients According to HER2 Status

Who this might be right for
Early Breast CancerMetastatic Breast CancerLocally Advanced Breast Cancer
MedSIR 18,533
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07795424
What this trial is testing

Culmerciclib Combined With Letrozole and Dual HER2 Blockade as Neoadjuvant Therapy for HR+/HER2+ Breast Cancer

Who this might be right for
Breast CancerHR Positive, HER2 Positive Breast Cancer
Shengjing Hospital 33
Testing effectiveness (Phase 2)Study completedNCT03735966
What this trial is testing

Neoadjuvant Study of Pyrotinib and Trastuzumab Plus Docetaxel and Carboplatin in HER2 Positive Breast Cancer Patients.

Who this might be right for
HER2 Positive Breast Cancer
Henan Cancer Hospital 75
Testing effectiveness (Phase 2)Study completedNCT00796978
What this trial is testing

Trastuzumab in Treating Older Women With Early-Stage Breast Cancer

Who this might be right for
Breast Cancer
Cynthia Owusu, MD 56
Early research (Phase 1)Not Yet RecruitingNCT07601620
What this trial is testing

Evaluate the Pharmacokinetics, Efficacy, and Safety of HLX319 vs. EU-Phesgo® in the Neoadjuvant Therapy of HER2-Positive Early or Locally Advanced Breast Cancer

Who this might be right for
HER2 + Breast Cancer
Shanghai Henlius Biotech 258
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07307287
What this trial is testing

SHR-A1811 Plus Pertuzumab as Neoadjuvant Therapy for Early or Locally Advanced HR-Positive HER2-Positive Breast Cancer: A Prospective, Open-Label, Phase II Study

Who this might be right for
SHR-A1811HER2-Postive Breast CancerHR+ Breast Cancer+2 more
Tianjin Medical University Cancer Institute and Hospital 30
Large-scale testing (Phase 3)Active Not RecruitingNCT03980054
What this trial is testing

Evaluating The Effects Of Pyrotinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer

Who this might be right for
Breast Cancer
Jiangsu HengRui Medicine Co., Ltd. 2,135
Not applicableUnknownNCT03756064
What this trial is testing

Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer

Who this might be right for
Breast CancerNeoplasm, BreastBreast Diseases
Zhejiang Cancer Hospital 100
Not applicableLooking for participantsNCT04543799
What this trial is testing

Evaluation of Sleep Quality in Prostate Cancer Patients Undergoing Treatment With Hormonal Therapeutic Approaches and in Patients With Full-resected Early Breast Cancer

Who this might be right for
Prostate CancerBreast Cancer
Oncology Institute of Southern Switzerland 60
Early research (Phase 1)Study completedNCT03505528
What this trial is testing

An Early Phase Study of Abraxane Combined With Phenelzine Sulfate in Patients With Metastatic or Advanced Breast Cancer

Who this might be right for
Metastatic Breast Cancer
EpiAxis Therapeutics 8
Testing effectiveness (Phase 2)Ended earlyNCT04066790
What this trial is testing

Pyrotinib or Trastuzumab Plus Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer

Who this might be right for
Breast Cancer
Shanghai Jiao Tong University School of Medicine 12
Testing effectiveness (Phase 2)Looking for participantsNCT07335081
What this trial is testing

CtDNA in HER2+ EBC Neoadjuvant Treatment

Who this might be right for
Breast Cancer
Shanghai Jiao Tong University School of Medicine 60
Testing effectiveness (Phase 2)Study completedNCT00545688
What this trial is testing

Pertuzumab in Combination With Herceptin in Patients With HER2 Positive Breast Cancer.

Who this might be right for
Breast Cancer
Hoffmann-La Roche 417
Next Page