Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Early and Locally Advanced Breast Cancer”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT05834764
What this trial is testing

Pyrotinib in Women With High-risk in Early Stage Breast Cancer

Who this might be right for
HER2-positive Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 188
Testing effectiveness (Phase 2)Study completedNCT04836520
What this trial is testing

SHR6390 Combined With Anastrozole for Preoperative Treatment of Breast Cancer.

Who this might be right for
Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05983094
What this trial is testing

Study of Utidelone Based Neoadjuvant Treatment on Early High-risk or Locally Advanced Breast Cancer

Who this might be right for
Breast CancerNeoadjuvant Therapy
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 181
Large-scale testing (Phase 3)Not Yet RecruitingNCT07269691
What this trial is testing

RaSOLVE: 125I Radioactive Seed Marking Effects on Pathological Complete Response Rate and Prognosis Post-Neoadjuvant Therapy in Early/Advanced Breast Cancer

Who this might be right for
Breast Cancer Early Stage Breast Cancer (Stage 1-3)Breast Cancer
Pengfei Qiu 194
Not applicableStudy completedNCT05945290
What this trial is testing

Pre-analytical Factors Affecting ctDNA Analysis in Early and Locally Advanced Breast Cancer

Who this might be right for
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+2 more
Mayo Clinic 114
Large-scale testing (Phase 3)Study completedNCT04629846
What this trial is testing

Study in Participants With Early-Stage or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive and Estrogen Receptor/Progesterone Receptor Negative Breast Cancer to Evaluate the Efficiency and Safety of Treatment With Trastuzumab Plus (+) QL1209/Pertuzumab + Docetaxel.

Who this might be right for
Breast Cancer
Qilu Pharmaceutical Co., Ltd. 517
Large-scale testing (Phase 3)Looking for participantsNCT07797218
What this trial is testing

Neoadjuvant Pyrotinib-to-pertuzumab in HER2+ eBC

Who this might be right for
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Shanghai Jiao Tong University School of Medicine 220
Testing effectiveness (Phase 2)Looking for participantsNCT06000917
What this trial is testing

Neoadjuvant TCHpy（Pyrotinib ，Trastuzumab，Carboplatin and Paclitaxel）for ER+/HER2+ Breast Cancer

Who this might be right for
Breast CancerNeoadjuvant
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 62
Large-scale testing (Phase 3)Study completedNCT03371017
What this trial is testing

The Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast Cancer

Who this might be right for
Triple Negative Breast Neoplasms
Hoffmann-La Roche 595
Early research (Phase 1)Looking for participantsNCT04969835
What this trial is testing

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

Who this might be right for
Salivary Gland TumorUrothelial CarcinomaOvarian Carcinoma+2 more
Avacta Life Sciences Ltd 158
Large-scale testing (Phase 3)Not Yet RecruitingNCT07294534
What this trial is testing

A Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX87in Combination With HLX22 or Pertuzumab in the Neoadjuvant Therapy of HER2-Positive Bresat Cancer

Who this might be right for
HER2 + Breast Cancer
Shanghai Henlius Biotech 817
Large-scale testing (Phase 3)Ended earlyNCT06038539
What this trial is testing

Efficacy and Safety of the Proposed Biosimilar Pertuzumab (PERT-IJS) Versus EU-Perjeta® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer

Who this might be right for
HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients
Biocon Biologics UK Ltd 55
Large-scale testing (Phase 3)Active Not RecruitingNCT04514419
What this trial is testing

Treatment of Breast Cancer With Trastuzumab + HS627/ Pertuzumab + Docetaxel

Who this might be right for
Breast Cancer
BioRay Pharmaceutical Co., Ltd. 408
Testing effectiveness (Phase 2)UnknownNCT05659056
What this trial is testing

Neoadjuvant Study With Pyrotinib and Trastuzumab and Abraxane in Patients With HER2-enriched Breast Cancer

Who this might be right for
Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 65
Testing effectiveness (Phase 2)UnknownNCT05945368
What this trial is testing

A Trial of Eribulin in Combination With HP Neoadjuvant Therapy in Patients With for HER2-Positive BC

Who this might be right for
HER2-positive Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 78
Large-scale testing (Phase 3)Active Not RecruitingNCT06747338
What this trial is testing

A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer

Who this might be right for
Early or Locally Advanced HER2-positive Breast Cancer
Shanghai JMT-Bio Inc. 520
Large-scale testing (Phase 3)Study completedNCT02149524
What this trial is testing

Compare the Effect of SB3 and Herceptin® in Women With HER2 Positive Breast Cancer

Who this might be right for
HER2 Positive Early or Locally Advanced Breast Cancer
Samsung Bioepis Co., Ltd. 875
Testing effectiveness (Phase 2)Looking for participantsNCT06927180
What this trial is testing

SHR-A1811 Plus Pertuzumab in the Neoadjuvant Treatment of HER2 Positive BC

Who this might be right for
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Henan Cancer Hospital 180
Very early researchWithdrawnNCT04088032
What this trial is testing

Neoadjuvant Study of Abemaciclib, Durvalumab, and an Aromatase Inhibitor Early Stage Breast Cancer

Who this might be right for
Breast Cancer FemaleLocally Advanced Breast CancerHormone Receptor Positive Malignant Neoplasm of Breast
Alison Stopeck
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07246317
What this trial is testing

Evaluation of Neoadjuvant Therapy With Trastuzumab, Pertuzumab, Docetaxel, and QL1706 in Early or Locally Advanced HER2+ Breast Cancer

Who this might be right for
Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 188
Next Page