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Results for “Eculizumab”

121 trials

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Showing 20 of 121 results

Large-scale testing (Phase 3)Study completedNCT04058158
What this trial is testing

Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Samsung Bioepis Co., Ltd. 50
Testing effectiveness (Phase 2)Study completedNCT01194804
What this trial is testing

E07-001: Safety and Efficacy Extension Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 27
Very early researchWithdrawnNCT03468140
What this trial is testing

Pilot Trial of Eculizumab Therapy to Reduce Preservation Injury in Human Macrosteatotic Liver Transplantation

Who this might be right for
End Stage Liver Disease
Yale University
Large-scale testing (Phase 3)Study completedNCT06764160
What this trial is testing

Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Eculizumab in Chinese Adults With gMG

Who this might be right for
Generalized Myasthenia Gravis (gMG)Refractory gMG
Alexion Pharmaceuticals, Inc. 15
Not applicableLooking for participantsNCT05966467
What this trial is testing

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

Who this might be right for
Neuromyelitis Optica Spectrum DisorderNMOSDAQP4+ NMOSD
Alexion Pharmaceuticals, Inc. 122
Not applicableNot Yet RecruitingNCT07182409
What this trial is testing

Efficacy and Safety of Monoclonal Antibody in Acute Phase of Neuromyelitis Optica Spectrum Disorder

Who this might be right for
NMOSD
First Affiliated Hospital of Chongqing Medical University 40
Testing effectiveness (Phase 2)Study completedNCT01303952
What this trial is testing

Therapy of Chronic Cold Agglutinin Disease With Eculizumab

Who this might be right for
Cold Agglutinin Disease
University Hospital, Essen 13
Large-scale testing (Phase 3)Study completedNCT05886244
What this trial is testing

Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) in China

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 25
Testing effectiveness (Phase 2)Study completedNCT01192399
What this trial is testing

Safety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 29
Not applicableStudy completedNCT05405777
What this trial is testing

A Retrospective Study to Evaluate the Clinical Outcome According to Treatment in aHUS Patients in South Korea

Who this might be right for
aHUS
Handok Inc. 97
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05646563
What this trial is testing

Study of NM8074 in Adult PNH Patients with Inadequate Response to Soliris

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
NovelMed Therapeutics 12
Post-approval studies (Phase 4)Study completedNCT04320602
What this trial is testing

Ravulizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Currently Treated With High-Dose Eculizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 18
Testing effectiveness (Phase 2)UnknownNCT04346797
What this trial is testing

CORIMUNO19-ECU: Trial Evaluating Efficacy and Safety of Eculizumab (Soliris) in Patients With COVID-19 Infection, Nested in the CORIMUNO-19 Cohort

Who this might be right for
SARS-CoV-2COVID19
Assistance Publique - Hôpitaux de Paris 120
Testing effectiveness (Phase 2)Study completedNCT00838513
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 15
Testing effectiveness (Phase 2)Study completedNCT00844428
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 5
Large-scale testing (Phase 3)Study completedNCT05876351
What this trial is testing

Eculizumab in Pediatric and Adult Participants With Atypical Hemolytic Uremic Syndrome (aHUS) in China

Who this might be right for
Atypical Hemolytic Uremic
Alexion Pharmaceuticals, Inc. 25
Testing effectiveness (Phase 2)Study completedNCT00844844
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 1
Testing effectiveness (Phase 2)Study completedNCT03472885
What this trial is testing

Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria With Inadequate Response to Eculizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alexion Pharmaceuticals, Inc. 12
Not applicableUnknownNCT03574506
What this trial is testing

Eculizumab Use in the Postpartum Period for the Treatment of Pregnancy Associated aHUS: A Case Series

Who this might be right for
Atypical Hemolytic Uremic SyndromePregnancy
Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia 50
Testing effectiveness (Phase 2)Study completedNCT01567085
What this trial is testing

Safety & Efficacy Of Eculizumab In The Prevention Of AMR In Sensitized Recipients Of A Kidney Transplant From A Deceased Donor

Who this might be right for
Stage V Chronic Kidney Disease
Alexion Pharmaceuticals, Inc. 80
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