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Results for “Eculizumab”

122 trials

Showing 20 of 122 results

Testing effectiveness (Phase 2)Study completedNCT00904826
What this trial is testing

An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica

Who this might be right for
Neuromyelitis OpticaDevic's Disease
Mayo Clinic 14
Testing effectiveness (Phase 2)Ended earlyNCT00727194
What this trial is testing

Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 14
Large-scale testing (Phase 3)Study completedNCT04060264
What this trial is testing

Clinical Trial of BCD-148 and Soliris® for the Treatment of Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Biocad 28
Not applicableUnknownNCT03574506
What this trial is testing

Eculizumab Use in the Postpartum Period for the Treatment of Pregnancy Associated aHUS: A Case Series

Who this might be right for
Atypical Hemolytic Uremic SyndromePregnancy
Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia 50
Testing effectiveness (Phase 2)Study completedNCT01192399
What this trial is testing

Safety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 29
Post-approval studies (Phase 4)Study completedNCT04320602
What this trial is testing

Ravulizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Currently Treated With High-Dose Eculizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 18
Testing effectiveness (Phase 2)Study completedNCT00935883
What this trial is testing

Complement Inhibition With Eculizumab for the Treatment of Non-Exudative Macular Degeneration (AMD)

Who this might be right for
Age-Related Macular Degeneration
Philip J. Rosenfeld, MD, PhD 60
Testing effectiveness (Phase 2)Study completedNCT00844428
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 5
Testing effectiveness (Phase 2)Ended earlyNCT01095887
What this trial is testing

Eculizumab to Prevent Antibody-mediated Rejection in ABO Blood Group Incompatible Living Donor Kidney Transplantation

Who this might be right for
Kidney Transplant
Mayo Clinic 6
Large-scale testing (Phase 3)Ended earlyNCT05131204
What this trial is testing

Efficacy and Safety of the Combination of Pozelimab and Cemdisiran Versus Continued Eculizumab or Ravulizumab Treatment in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals 3
Early research (Phase 1)Study completedNCT01327573
What this trial is testing

Eculizumab Therapy for Chronic Complement-Mediated Injury in Kidney Transplantation

Who this might be right for
Kidney; Complications, Allograft
Sanjay Kulkarni 16
Not applicableStudy completedNCT01770951
What this trial is testing

A Retrospective, Observational, Non-interventional Trial to Assess Eculizumab Treatment Effect in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 30
Not applicableUnknownNCT06098378
What this trial is testing

Study of Patients With Thrombotic Microangiopathy Associated With Mitomycin C, Treated or Not With Eculizumab

Who this might be right for
Thrombotic Microangiopathies
University Hospital, Strasbourg, France 30
Testing effectiveness (Phase 2)Study completedNCT01756508
What this trial is testing

Eculizumab for Prevention and Treatment of Kidney Graft Reperfusion Injury

Who this might be right for
End-Stage Renal DiseaseKidney FailureGraft Reperfusion Injury
Russian Academy of Medical Sciences 57
Large-scale testing (Phase 3)Active Not RecruitingNCT04432584
What this trial is testing

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Hoffmann-La Roche 190
Large-scale testing (Phase 3)Study completedNCT04859608
What this trial is testing

Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU)

Who this might be right for
Hemolytic-Uremic Syndrome, Atypical
University Hospital, Tours 40
Not applicableStudy completedNCT05405777
What this trial is testing

A Retrospective Study to Evaluate the Clinical Outcome According to Treatment in aHUS Patients in South Korea

Who this might be right for
aHUS
Handok Inc. 97
Large-scale testing (Phase 3)Study completedNCT02145182
What this trial is testing

Prevention of Delayed Graft Function Using Eculizumab Therapy (PROTECT Study)

Who this might be right for
Delayed Graft Function
Alexion Pharmaceuticals, Inc. 288
Testing effectiveness (Phase 2)Ended earlyNCT01106027
What this trial is testing

Dosing Regimen of Eculizumab Added to Conventional Treatment in Positive Crossmatch Deceased Donor Kidney Transplant

Who this might be right for
Kidney Transplant
Mayo Clinic 2
Large-scale testing (Phase 3)Study completedNCT04679103
What this trial is testing

A Safety and Immunogenicity Study in Long-term Treatment of Eculizumab (JSC "GENERIUM", Russian Federation)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
AO GENERIUM 50
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