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Results for “Eculizumab”

124 trials

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Showing 20 of 124 results

Not applicableLooking for participantsNCT05805202
What this trial is testing

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 112
Large-scale testing (Phase 3)Study completedNCT03759366
What this trial is testing

Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG)

Who this might be right for
Myasthenia GravisMyasthenia Gravis, Juvenile FormMyasthenia Gravis, Generalized
Alexion Pharmaceuticals, Inc. 12
Large-scale testing (Phase 3)Study completedNCT04058158
What this trial is testing

Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Samsung Bioepis Co., Ltd. 50
Large-scale testing (Phase 3)Study completedNCT04558918
What this trial is testing

Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Novartis Pharmaceuticals 97
Testing effectiveness (Phase 2)Study completedNCT02591862
What this trial is testing

Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria (PNH)
AKARI Therapeutics 1
Large-scale testing (Phase 3)Study completedNCT03056040
What this trial is testing

ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alexion Pharmaceuticals, Inc. 202
Large-scale testing (Phase 3)Ended earlyNCT04155424
What this trial is testing

The Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder

Who this might be right for
Neuromyelitis OpticaNeuromyelitis Optica Spectrum Disorder
Alexion Pharmaceuticals, Inc. 5
Testing effectiveness (Phase 2)Study completedNCT00844545
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 16
Early research (Phase 1)Study completedNCT04027803
What this trial is testing

Comparative Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of Single Intravenous Doses of BCD-148 and Soliris®

Who this might be right for
Healthy Subjects
Biocad 78
Large-scale testing (Phase 3)Study completedNCT00122304
What this trial is testing

Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab

Who this might be right for
Hemoglobinuria, Paroxysmal
Alexion Pharmaceuticals, Inc. 85
Large-scale testing (Phase 3)Study completedNCT00130000
What this trial is testing

Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Hemoglobinuria, Nocturnal
National Heart, Lung, and Blood Institute (NHLBI) 87
Testing effectiveness (Phase 2)Study completedNCT02727608
What this trial is testing

Complement Inhibitor Eculizumab in Clinical Islet Transplantation

Who this might be right for
Diabetes Mellitus
Uppsala University 3
Testing effectiveness (Phase 2)UnknownNCT02029378
What this trial is testing

Inhibition of Complement Activation (Eculizumab) in Guillain-Barre Syndrome Study

Who this might be right for
Gullian Barre Syndrome
NHS Greater Glasgow and Clyde 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT07184840
What this trial is testing

Eculizumab For the Acute Attack of Neuromyelitis Optica Spectrum Disorder

Who this might be right for
Neuromyelitis Optica Spectrum Disorder Attack
Tianjin Medical University General Hospital 110
Not applicableStudy completedNCT06448715
What this trial is testing

Real-World Treatment Study of Soliris (Eculizumab)

Who this might be right for
Observational
AstraZeneca 11
Not applicableStudy completedNCT01770951
What this trial is testing

A Retrospective, Observational, Non-interventional Trial to Assess Eculizumab Treatment Effect in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 30
Large-scale testing (Phase 3)Study completedNCT00112983
What this trial is testing

Eculizumab in Treating Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Leukemia
Jonsson Comprehensive Cancer Center
Not applicableEnded earlyNCT01522170
What this trial is testing

AHUS Observational Long Term Follow-Up

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 94
Large-scale testing (Phase 3)Study completedNCT02301624
What this trial is testing

Extension Study of ECU-MG-301 to Evaluate Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis

Who this might be right for
Refractory Generalized Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 117
Large-scale testing (Phase 3)Looking for participantsNCT07420296
What this trial is testing

Modified Zipper Therapy for AQP4-IgG Positive Neuromyelitis Optica Spectrum Disorder

Who this might be right for
Neuromyelitis Optica Spectrum Disorders (NMOSD)
Tianjin Medical University General Hospital 198
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