Early research (Phase 1)Study completedNCT05927415What this trial is testingTest How Kidney Problems Influence the Blood Concentrations of EfgartigimodWho this might be right forRenal Impairment argenx 33
Not applicableNot Yet RecruitingNCT07182409What this trial is testingEfficacy and Safety of Monoclonal Antibody in Acute Phase of Neuromyelitis Optica Spectrum DisorderWho this might be right forNMOSD First Affiliated Hospital of Chongqing Medical University 40
Large-scale testing (Phase 3)Study completedNCT04735432What this trial is testingEvaluating the Pharmacodynamic Noninferiority of Efgartigimod PH20 SC Administered Subcutaneously as Compared to Efgartigimod Administered Intravenously in Patients With Generalized Myasthenia GravisWho this might be right forGeneralized Myasthenia Gravis argenx 110
Large-scale testing (Phase 3)Active Not RecruitingNCT06558279What this trial is testingAssess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular Myasthenia GravisWho this might be right forMyasthenia Gravis, Ocular argenx 141
Testing effectiveness (Phase 2)Study completedNCT06203457What this trial is testingOpen-Label Extension Study to Evaluate the Safety of Efgartigimod in Adult Patients With Primary Sjögren's SyndromeWho this might be right forPrimary Sjögren's Syndrome argenx 24
Large-scale testing (Phase 3)Study completedNCT05267600What this trial is testingEfgartigimod PH20 SC in Adult Participants With Bullous PemphigoidWho this might be right forBullous Pemphigoid argenx 98
Post-approval studies (Phase 4)Looking for participantsNCT06860633What this trial is testingTreatment of Myasthenia Gravis Exacerbation or Crisis With EfgartigimodWho this might be right forMyasthenia Gravis CrisisMyasthenia Gravis ExacerbationsAChR Myasthenia Gravis University of Colorado, Denver 20
Large-scale testing (Phase 3)Ended earlyNCT05681481What this trial is testingEvaluate the Long-term Safety, Tolerability and Efficacy of Efgartigimod PH20 SC in Adult Participants With Bullous PemphigoidWho this might be right forBullous Pemphigoid argenx 64
Testing effectiveness (Phase 2)Looking for participantsNCT06453694What this trial is testingEfgartigimod for the Treatment of Acute Optic NeuritisWho this might be right forOptic Neuritis Anastasia Vishnevetsky, MD, MPH 20
Post-approval studies (Phase 4)Not Yet RecruitingNCT06688253What this trial is testingIntravenous Human IgG1 Fc Fragment (Efgartigimod) in Myasthenic CrisisWho this might be right forMyasthenia Gravis Crisis Rambam Health Care Campus 16
Not applicableNot Yet RecruitingNCT07079020What this trial is testingEfgartigimod for Consolidation Therapy in gMGWho this might be right forMyasthenia Gravis Da, Yuwei, M.D. 130
Testing effectiveness (Phase 2)Active Not RecruitingNCT04280718What this trial is testingAssess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves)Who this might be right forChronic Inflammatory Demyelinating Polyneuropathy (CIDP) argenx 229
Post-approval studies (Phase 4)Looking for participantsNCT06909214What this trial is testingEvaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG)Who this might be right forNew Onset Generalized Myasthenia Gravis (gMG) argenx 30
Not applicableLooking for participantsNCT06299748What this trial is testingA Worldwide Pregnancy Safety Study to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to Efgartigimod During Pregnancy and/or Breastfeeding.Who this might be right forMyasthenia GravisCIDP - Chronic Inflammatory Demyelinating Polyneuropathy argenx 279
Large-scale testing (Phase 3)Active Not RecruitingNCT06307626What this trial is testingEfgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease.Who this might be right forThyroid Eye Disease argenx 105
Not applicableApproved For MarketingNCT04777734What this trial is testingEfgartigimod Expanded Access for Generalized Myasthenia GravisWho this might be right forGeneralized Myasthenia Gravis argenx
Large-scale testing (Phase 3)Not Yet RecruitingNCT07231523What this trial is testingEFG vs IVIG in TAMGWho this might be right forEfgartigimodIntravenous ImmunoglobulinMyasthenia Gravis Associated With Thymoma Shanghai Zhongshan Hospital 64
Large-scale testing (Phase 3)Study completedNCT04598451What this trial is testingAssess the Efficacy and Safety of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)Who this might be right forPemphigus VulgarisPemphigus Foliaceus argenx 222
Large-scale testing (Phase 3)WithdrawnNCT04274452What this trial is testingAssess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP)Who this might be right forPrimary Immune Thrombocytopenia (ITP) argenx
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07011589What this trial is testingTargeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART)Who this might be right forEpidermolysis Bullosa (EB)Epidermolysis Bullosa AcquisitaRecessive Dystrophic Epidermolysis Bullosa+1 more M. Peter Marinkovich 18