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Results for “Elderly Unfit Patients”

34 trials

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Showing 20 of 34 results

Testing effectiveness (Phase 2)Ended earlyNCT05144009
What this trial is testing

Loncastuximab Tesirine and Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Participants With Diffuse Large B-cell Lymphoma (DLBCL)

Who this might be right for
Diffuse Large B-cell Lymphoma
ADC Therapeutics S.A. 41
Testing effectiveness (Phase 2)UnknownNCT03809780
What this trial is testing

Study to Demonstrate Clinical Benefit of Lenalidomide and Dexamethasone

Who this might be right for
Multiple Myeloma
Kosin University Gospel Hospital 70
Testing effectiveness (Phase 2)UnknownNCT04254640
What this trial is testing

Efficacy and Safety of Cladribine in Combination With CAG in Newly Diagnosed Unfit Patients With AML

Who this might be right for
Acute Myeloid LeukemiaElderly PatientsNewly Diagnosed
Sun Yat-sen University 34
Testing effectiveness (Phase 2)UnknownNCT04541277
What this trial is testing

Combined Inhibition of PD-1 and DNA Hypomethylating Agent +/- Chemotherapy in High-risk AML or Elderly Patients With AML Who Are Unfit for Intensive Chemotherapy

Who this might be right for
Acute Myeloid Leukemia, in Relapsed or RefractoryAcute Myeloid Leukemia, Elderly, UnfitAcute Myeloid Leukemia With Positive Minimal Residual Disease
Chinese PLA General Hospital 55
Testing effectiveness (Phase 2)Ended earlyNCT02495454
What this trial is testing

GA101-miniCHOP Regimen for the Treatment of Elderly Unfit Patients With Diffuse Large B-cell Non-Hodgkin's Lymphoma

Who this might be right for
CD20 Positive Diffuse Large B-cell LymphomaElderly Unfit Patients
Fondazione Italiana Linfomi - ETS 34
Large-scale testing (Phase 3)Study completedNCT01237808
What this trial is testing

Study of Low-Dose Cytarabine and Etoposide With or Without All-Trans Retinoic Acid in Older Patients Not Eligible for Intensive Chemotherapy With Acute Myeloid Leukemia and NPM1 Mutation

Who this might be right for
Acute Myeloid Leukemia (AML)
University of Ulm 144
Large-scale testing (Phase 3)UnknownNCT04490707
What this trial is testing

Study of Azacytidine Combined With Lenalidomide As Maintenance Therapy Based on MRD Monitoring in AML

Who this might be right for
Acute Myeloid Leukemia in Remission
Ge Zheng 60
Testing effectiveness (Phase 2)Study completedNCT03677154
What this trial is testing

Trial of Mosunetuzumab (BTCT4465A) as Consolidation Therapy in Participants With Diffuse Large B-Cell Lymphoma Following First-Line Immunochemotherapy and as Monotherapy or in Combination With Polatuzumab Vedotin in Elderly/Unfit Participants With Previously Untreated Diffuse Large B-Cell Lymphoma

Who this might be right for
Diffuse Large B-cell Lymphoma
Hoffmann-La Roche 188
Testing effectiveness (Phase 2)Looking for participantsNCT07205731
What this trial is testing

Phase II Study Evaluating Safety and Efficacy of Tislelizumab for Elderly Patients Unfit for Chemotherapy, With Advanced Esophageal Squamous-cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
University Hospital, Clermont-Ferrand 95
Testing effectiveness (Phase 2)Looking for participantsNCT06656598
What this trial is testing

Adjuvant Chemotherapy +/- Cemiplimab and Sequential Hypofractionated Radiotherapy in Unfit or Elderly Patients With Stage III Lung Cancer

Who this might be right for
Stage III NSCLC
Intergroupe Francophone de Cancerologie Thoracique 152
Not applicableUnknownNCT05265663
What this trial is testing

Stereotactic Radiotherapy vs Best Supportive Care in Unfit Pancreatic Cancer Patients

Who this might be right for
Pancreatic Cancer Non-resectable
Amsterdam UMC, location VUmc 98
Early research (Phase 1)WithdrawnNCT04973618
What this trial is testing

Study of APVO436 in Elderly or Unfit Patients With Newly Diagnosed AML

Who this might be right for
AML
Aptevo Therapeutics
Not applicableLooking for participantsNCT07117422
What this trial is testing

Venetoclax-Decitabine in Untreated Elderly/Unfit AML

Who this might be right for
AML, Adult
The Second Hospital of Hebei Medical University 39
Testing effectiveness (Phase 2)UnknownNCT03949062
What this trial is testing

Study Evaluating the Safety and Efficacy of iR2 in Untreated and Unfit Elderly Patients With DLBCL

Who this might be right for
Diffuse Large B Cell Lymphoma
Ruijin Hospital 30
Large-scale testing (Phase 3)UnknownNCT06073730
What this trial is testing

Comparison of the Efficacy and Safety of Venetoclax in Combination With 3 Days Decitabine (DEC3-VEN) vs. Venetoclax in Combination With Azacitidine (VIALE-A) in the Treatment of Elderly Patients or Unfit, New-diagnosis Acute Myeloid Leukemia Patients

Who this might be right for
Elderly AML PatientsUnfit, New-diagnosis AMLAcute Myeloid Leukemia+2 more
The Second Affiliated Hospital of Kunming Medical University 154
Testing effectiveness (Phase 2)UnknownNCT04824924
What this trial is testing

Venetoclax in Combination With Low-dose HHT, G-CSF, and AZA as First-line Treatment for Newly Diagnosed Elderly AML Patients Unfit for Intensive Chemotherapy

Who this might be right for
Leukemia, Myeloid, Acute
Shanghai Jiao Tong University School of Medicine 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04351256
What this trial is testing

Thoracic Radiotherapy Plus Durvalumab in Elderly and/or Frail NSCLC Stage III Patients Unfit for Chemotherapy

Who this might be right for
NSCLC, Stage III
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 51
Testing effectiveness (Phase 2)UnknownNCT01488344
What this trial is testing

Phase I/II Trial: BIBF 1120 Added to Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
University Hospital Muenster 140
Testing effectiveness (Phase 2)Study completedNCT01415011
What this trial is testing

Efficacy and Safety Study of Afatinib to Treat Lung Cancer Patients

Who this might be right for
Carcinoma, Non-Small-Cell Lung
University College, London 39
Testing effectiveness (Phase 2)Study completedNCT02015208
What this trial is testing

Ruxolitinib in the Treatment of Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic Leukemia
Sunnybrook Health Sciences Centre 13
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