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Results for “Elevated LDL-Cholesterol (LDL-C)”

96 trials

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Showing 20 of 96 results

Large-scale testing (Phase 3)Study completedNCT04929249
What this trial is testing

Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE)

Who this might be right for
Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals 450
Early research (Phase 1)Study completedNCT01671085
What this trial is testing

LY3015014 in Healthy Participants With High Cholesterol

Who this might be right for
Healthy VolunteersHypercholesterolemia
Eli Lilly and Company 13
Large-scale testing (Phase 3)Study completedNCT03399370
What this trial is testing

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol

Who this might be right for
ASCVDElevated Cholesterol
The Medicines Company 1,561
Large-scale testing (Phase 3)Study completedNCT05079919
What this trial is testing

Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

Who this might be right for
Severe Hypertriglyceridemia
Ionis Pharmaceuticals, Inc. 617
Large-scale testing (Phase 3)Study completedNCT00239330
What this trial is testing

Direct Statin Comparison of LDL-C Values: an Evaluation of Rosuvastatin Therapy

Who this might be right for
Hypercholesteremia
AstraZeneca 824
Early research (Phase 1)Study completedNCT05787002
What this trial is testing

Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.

Who this might be right for
Dyslipidemia
AstraZeneca 16
Post-approval studies (Phase 4)Looking for participantsNCT06501443
What this trial is testing

LATAM LOWERS LDL-C

Who this might be right for
Hypercholesterolaemia
Novartis Pharmaceuticals 520
Early research (Phase 1)Study completedNCT01437059
What this trial is testing

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Who this might be right for
Elevated LDL-Cholesterol (LDL-C)
Alnylam Pharmaceuticals 32
Large-scale testing (Phase 3)Study completedNCT01516879
What this trial is testing

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study

Who this might be right for
Hypercholesterolemia
Amgen 905
Early research (Phase 1)Study completedNCT00055042
What this trial is testing

Laser and Antioxidant Treatment of Diabetic Macular Edema

Who this might be right for
Macular EdemaDiabetes Mellitus
National Eye Institute (NEI) 40
Testing effectiveness (Phase 2)Study completedNCT02597127
What this trial is testing

Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C)

Who this might be right for
Atherosclerotic Cardiovascular DiseaseFamilial HypercholesterolemiaDiabetes
The Medicines Company 501
Early research (Phase 1)Study completedNCT06742853
What this trial is testing

Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.

Who this might be right for
Dyslipidemia
AstraZeneca 81
Large-scale testing (Phase 3)Study completedNCT03397121
What this trial is testing

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial HypercholesterolemiaElevated Cholesterol
The Medicines Company 482
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Large-scale testing (Phase 3)Study completedNCT01953328
What this trial is testing

Study of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients With Advanced Cardiovascular Risk

Who this might be right for
Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events
Amgen 409
Large-scale testing (Phase 3)Study completedNCT00050479
What this trial is testing

Laser and Medical Treatment of Diabetic Macular Edema

Who this might be right for
Macular Degeneration
National Eye Institute (NEI) 100
Not applicableStudy completedNCT00931320
What this trial is testing

Investigation Into the RAtio of LDL-CHolestEroL to HDL-Cholesterol Improvement After Statin Treatment in Korean Patients

Who this might be right for
Dyslipidemias
AstraZeneca 3,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06750341
What this trial is testing

Study of QLC7401 in the Treatment of Primary Hypercholesterolemia or Mixed Hyperlipidemia With Elevated LDL Cholesterol

Who this might be right for
Primary Hypercholesterolemia or Mixed Hyperlipidemia
Qilu Pharmaceutical Co., Ltd. 156
Early research (Phase 1)Enrolling By InvitationNCT06504043
What this trial is testing

A Study on Evaluating the Safety of HST101 in Healthy Chinese Participants

Who this might be right for
HypercholesterolemiaHealthy VolunteersLDL-Cholesterol
Hasten Biopharmaceutical Co., Ltd. 30
Testing effectiveness (Phase 2)Study completedNCT05421078
What this trial is testing

A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.

Who this might be right for
DyslipidemiaHypercholesterolemiaHigh Cholesterol
NewAmsterdam Pharma 102
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