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Results for “Elevated LDL-Cholesterol (LDL-C)”

103 trials

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Showing 20 of 103 results

Early research (Phase 1)Not Yet RecruitingNCT07074236
What this trial is testing

Pharmacokinetics and Pharmacodynamics Study

Who this might be right for
Primary Hypercholesterolemia or Combined Hyperlipidemia Characterized by Elevated LDL-C
Qilu Pharmaceutical Co., Ltd. 48
Not applicableStudy completedNCT00347217
What this trial is testing

Observational to Investigate the Efficacy of CRESTOR 5mg in Reaching LDL-C Target Goals in Patients Who Are at High Risk for a Cardiovascular Event

Who this might be right for
Hypercholesteremia
AstraZeneca 3,840
Early research (Phase 1)Study completedNCT01437059
What this trial is testing

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Who this might be right for
Elevated LDL-Cholesterol (LDL-C)
Alnylam Pharmaceuticals 32
Large-scale testing (Phase 3)Study completedNCT02585895
What this trial is testing

Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment

Who this might be right for
Hypercholesterolemia
Amgen 39
Testing effectiveness (Phase 2)Study completedNCT04753606
What this trial is testing

Randomized Study of Obicetrapib as an Adjunct to Statin Therapy

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia
NewAmsterdam Pharma 120
Early research (Phase 1)Study completedNCT05905068
What this trial is testing

Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects

Who this might be right for
To Reduce the LDL-C Level in Hypercholesteremia Adult PatientsCombination for Subgroup High LDL-c Patients With Other Comorbidities
Ikaria Bioscience Pty Ltd 32
Large-scale testing (Phase 3)Study completedNCT00654485
What this trial is testing

COMETS - Compare the Efficacy of Rosuvastatin With Atorvastatin and Placebo in the Treatment of Non-Diabetic, Non-Atheroscleric, Metabolic Syndrome Subjects

Who this might be right for
Metabolic Syndrome
AstraZeneca 940
Large-scale testing (Phase 3)Study completedNCT02739984
What this trial is testing

Evaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemia

Who this might be right for
HypercholesterolemiaMixed DyslipidemiaType 2 Diabetes
Amgen 424
Not applicableStudy completedNCT00931320
What this trial is testing

Investigation Into the RAtio of LDL-CHolestEroL to HDL-Cholesterol Improvement After Statin Treatment in Korean Patients

Who this might be right for
Dyslipidemias
AstraZeneca 3,000
Testing effectiveness (Phase 2)Study completedNCT05266586
What this trial is testing

Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia
NewAmsterdam Pharma 119
Not applicableStudy completedNCT02504736
What this trial is testing

Colesevelam, Lipids And Sugars, South Asian Canadian Trial

Who this might be right for
Dyslipidemia
Canadian Collaborative Research Network 90
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Early research (Phase 1)Study completedNCT03593785
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 in Healthy Male Subjects With Increased Elevated LDL-C Levels.

Who this might be right for
Hypercholesterolemia
AstraZeneca 73
Testing effectiveness (Phase 2)Study completedNCT01375764
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Who this might be right for
Hyperlipidemia
Amgen 160
Large-scale testing (Phase 3)Study completedNCT03001076
What this trial is testing

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)

Who this might be right for
HypercholesterolemiaAtherosclerosisStatin Adverse Reaction
Esperion Therapeutics, Inc. 269
Large-scale testing (Phase 3)Study completedNCT03397121
What this trial is testing

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial HypercholesterolemiaElevated Cholesterol
The Medicines Company 482
Early research (Phase 1)Study completedNCT05912296
What this trial is testing

A Single and Multiple Ascending Doses Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RBD7022

Who this might be right for
Hyperlipemia
Suzhou Ribo Life Science Co. Ltd. 80
Large-scale testing (Phase 3)Study completedNCT02392559
What this trial is testing

Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Amgen 158
Post-approval studies (Phase 4)Study completedNCT07255820
What this trial is testing

Dual vs Triple Lipid-Lowering Therapy in Type 2 Diabetes Mellitus Patients With Elevated LDL Cholesterol

Who this might be right for
Type 2 Diabetes MellitusHypercholesterolemia / Elevated LDL Cholesterol
Bahria University 126
Large-scale testing (Phase 3)Looking for participantsNCT06597006
What this trial is testing

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 9
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