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Results for “Elevated Tumor-Infiltrating Lymphocytes”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Ended earlyNCT01814046
What this trial is testing

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma

Who this might be right for
Metastatic Ocular MelanomaMetastatic Uveal Melanoma
National Cancer Institute (NCI) 24
Early research (Phase 1)Looking for participantsNCT06047977
What this trial is testing

Tumor Infiltrating Lymphocyte Therapy for Pediatric High Risk Solid Tumors

Who this might be right for
Lymphocytes
H. Lee Moffitt Cancer Center and Research Institute 30
Testing effectiveness (Phase 2)Ended earlyNCT03610490
What this trial is testing

Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma

Who this might be right for
Malignant Solid NeoplasmMetastatic Colorectal AdenocarcinomaMetastatic Ovarian Carcinoma+9 more
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Looking for participantsNCT06078384
What this trial is testing

Pembrolizumab and Chemotherapy Treatment or no Treatment Guided by the Level of TILs in Resected Early-stage TNBC

Who this might be right for
Triple-negative Breast Cancer
UNICANCER 354
Testing effectiveness (Phase 2)Looking for participantsNCT06630611
What this trial is testing

Evaluation of a Pragmatic Approach to Adoptive Cell Therapy (ACT) Using an IL2 Analog (ANV419) vs High Dose IL2 After Tumor Infiltrating Lymphocytes (TIL) Therapy in Patients With Melanoma, NSCLC and Cervical Cancer (PragmaTIL)

Who this might be right for
MelanomaNon Small Cell Lung CancerCervical Cancer
Vall d'Hebron Institute of Oncology 40
Not applicableLooking for participantsNCT06476119
What this trial is testing

OPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal Tumor-infiltrating Lymphocytes

Who this might be right for
Breast Cancer Stage ITriple Negative Breast Cancer (TNBC)
The Netherlands Cancer Institute 490
Testing effectiveness (Phase 2)Ended earlyNCT01995344
What this trial is testing

TIL Therapy in Metastatic Melanoma and IL2 Dose Assessment

Who this might be right for
Metastatic Melanoma
The Christie NHS Foundation Trust 2
Testing effectiveness (Phase 2)Study completedNCT01993719
What this trial is testing

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
National Cancer Institute (NCI) 33
Testing effectiveness (Phase 2)Looking for participantsNCT07743190
What this trial is testing

A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs)

Who this might be right for
Triple Negative Breast Cancer (TNBC)Elevated Tumor-Infiltrating Lymphocytes
Medical University of South Carolina 55
Early research (Phase 1)WithdrawnNCT06190249
What this trial is testing

Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma

Who this might be right for
Stage IIIB MelanomaStage IIIC MelanomaStage IIID Melanoma
James Isaacs, MD
Testing effectiveness (Phase 2)Study completedNCT02500576
What this trial is testing

Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma

Who this might be right for
Metastatic MelanomaStage IIIB Cutaneous Melanoma AJCC v7Stage IIIC Cutaneous Melanoma AJCC v7+1 more
M.D. Anderson Cancer Center 18
Early research (Phase 1)Ended earlyNCT03991741
What this trial is testing

Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid Tumors

Who this might be right for
Metastatic MelanomaLocally Advanced Refractory/Recurrent MelanomaMetastatic Head and Neck Cancer+1 more
Gregory Daniels 3
Early research (Phase 1)Active Not RecruitingNCT05768347
What this trial is testing

Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC

Who this might be right for
Urothelial CarcinomaNon-Invasive Bladder Urothelial Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 9
Early research (Phase 1)Active Not RecruitingNCT01883297
What this trial is testing

"Re-Stimulated" TILs And IL-2 Therapy for Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
RecurrentPlatinum-resistantHigh Grade Serous Ovarian Cancer+2 more
University Health Network, Toronto 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT03449108
What this trial is testing

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

Who this might be right for
Bone SarcomaDedifferentiated ChondrosarcomaGiant Cell Tumor of Bone+13 more
M.D. Anderson Cancer Center 30
Not applicableEnrolling By InvitationNCT06646263
What this trial is testing

Cellular Immune Responses in Triple-negative Breast Cancer - High Throughput Immunogenetic Studies

Who this might be right for
Triple Negative Breast Cancer
Institute of Applied Biosciences 150
Not applicableStudy completedNCT01005745
What this trial is testing

Lymphodepletion Plus Adoptive Cell Transfer With High Dose IL-2 in Patients With Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
H. Lee Moffitt Cancer Center and Research Institute 19
Testing effectiveness (Phase 2)Looking for participantsNCT04114136
What this trial is testing

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Who this might be right for
MelanomaNSCLCHepatocellular Carcinoma+5 more
Dan Zandberg 72
Not applicableEnded earlyNCT03922776
What this trial is testing

Phenotypic Characterization Tumor-infiltrating Lymphocytes at Diagnosis and After Chemotherapy in Ovarian Cancer

Who this might be right for
Ovarian Cancer Stage IIICFallopian Tube Cancer Stage IIICFallopian Tube Cancer Stage IV+1 more
Centre Oscar Lambret 36
Testing effectiveness (Phase 2)Study completedNCT01858558
What this trial is testing

Tadalafil and Lenalidomide Maintenance With or Without Activated Marrow Infiltrating Lymphocytes (MILs) in High Risk Myeloma

Who this might be right for
Multiple Myeloma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 102
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