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Results for “Ensartinib”

31 trials

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Showing 20 of 31 results

Early research (Phase 1)Study completedNCT05665283
What this trial is testing

A Single Dose BE Study of X-396 in Healthy Volunteers Under Fasted Conditions

Who this might be right for
Bioequivalency
Xcovery Holdings, Inc. 32
Testing effectiveness (Phase 2)Looking for participantsNCT05241028
What this trial is testing

Adjuvant Therapy of Ensartinib in Stage IB-IIIA ALK-positive Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Hebei Medical University Fourth Hospital 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT05491811
What this trial is testing

Ensartinib in Combination With Bevacizumab in ALK-positive NSCLC Patients With TP53 Mutation

Who this might be right for
Non-Small Cell Lung Cancer
Sun Yat-sen University 47
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Not applicableNot Yet RecruitingNCT06736561
What this trial is testing

Real-world Clinical Study on the Efficacy and Safety of Ensartinib As Neoadjuvant Treatment for Anaplastic Lymphoma Kinase (ALK) Positive Non-small Cell Lung Cancer (NSCLC) Patients.

Who this might be right for
ALK PositiveEnsartinibNSCLC+1 more
Harbin Medical University 100
Testing effectiveness (Phase 2)UnknownNCT04415320
What this trial is testing

X-396 (Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases

Who this might be right for
Lung Cancer, Nonsmall CellBrain Metastases
Betta Pharmaceuticals Co., Ltd. 37
Early research (Phase 1)Study completedNCT03510611
What this trial is testing

Investigate the Food Effect on the Pharmacokinetics of Ensartinib Capsules in Chinese Healthy Volunteers.

Who this might be right for
Non-Small Cell Lung Cancer
Betta Pharmaceuticals Co., Ltd. 24
Post-approval studies (Phase 4)Not Yet RecruitingNCT07671560
What this trial is testing

Efficacy and Safety of Ensartinib Combined With Anlotinib in Lorlatinib-Resistant ALK-Positive NSCLC

Who this might be right for
ALK-positive, Locally Advanced or Metastatic (TNM Stage IIIB-IV) Non-small Cell Lung Cancer That Has Developed Resistance to Prior Treatment With Lorlatinib
Qiming Wang 80
Testing effectiveness (Phase 2)UnknownNCT05380024
What this trial is testing

Ensartinib as Neoadjuvant Therapy for Patients With ALK Positive Resectable Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Peking University Cancer Hospital & Institute 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT03420508
What this trial is testing

Treating Patients With Melanoma and ALK Alterations With Ensartinib

Who this might be right for
Melanoma
Memorial Sloan Kettering Cancer Center 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT03753685
What this trial is testing

X-396(Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases

Who this might be right for
Nonsmall Cell Lung CancerBrain Metastases
Fudan University 27
Early research (Phase 1)UnknownNCT06492525
What this trial is testing

Evaluate The Effect Of Rifampicin Or Ltraconazole On Pharmacokinetics Of Ensartinib In Healthy Volunteers

Who this might be right for
Healthy
Betta Pharmaceuticals Co., Ltd. 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07235306
What this trial is testing

Ensartinib After Chemoradiotherapy in Stage III ALK-Mutated NSCLC

Who this might be right for
NSCLC Stage IIIEnsartinibChemoradiotherapy+1 more
Shanghai Pulmonary Hospital, Shanghai, China 45
Not applicableAvailableNCT04146571
What this trial is testing

Expanded Access to Ensartinib for Participants With ALK+ NSCLC

Who this might be right for
Non-Small Cell Lung CancerALK Gene Rearrangement Positive
Xcovery Holdings, Inc.
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06762327
What this trial is testing

Ensartinib in the Treatment of ALK Positive or MET Exon 14 Skipping Anvanced Solid Tumors Excluded Lung Cancer

Who this might be right for
Solid Tumors
Nanjing First Hospital, Nanjing Medical University 20
Testing effectiveness (Phase 2)Study completedNCT02898116
What this trial is testing

Phase 1/2 Study of Ensartinib and Durvalumab, in ALK-rearranged Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung CancerCarcinomaNSCLC
Ludwig Institute for Cancer Research 2
Testing effectiveness (Phase 2)Looking for participantsNCT07354061
What this trial is testing

Neoadjuvant Therapy With Ensartinib Combined With Chemotherapy for ALK-positive Non - Small Cell Lung Cancer (NSCLC)

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
Tang-Du Hospital 20
Early research (Phase 1)Active Not RecruitingNCT04837716
What this trial is testing

Ensartinib, Carboplatin, Pemetrexed and Bevacizumab for the Treatment of Stage IIIC or IV or Recurrent ALK-Positive Non-small Cell Lung Cancer

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IIIC Lung Cancer AJCC v8+3 more
M.D. Anderson Cancer Center 12
Large-scale testing (Phase 3)UnknownNCT05341583
What this trial is testing

Ensartinib as Adjuvant Treatment in Anaplastic Lymphoma Kinase (ALK) Positive Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Betta Pharmaceuticals Co., Ltd. 202
Post-approval studies (Phase 4)Not Yet RecruitingNCT06785584
What this trial is testing

Efficacy and Safety of Ensartinib in Neoadjuvant Therapy for Stage IIA - IIIB (Operable or Potentially Operable) ALK-Positive Lung Adenocarcinoma ：A Multicenter, Real-World Clinical Study

Who this might be right for
ALK-positive Advanced NSCLCALK-positive Non-small Cell Lung Cancer (NSCLC)MPR+1 more
Fujian Medical University Union Hospital 30
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