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Results for “Entinostat”

72 trials

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Showing 20 of 72 results

Early research (Phase 1)Study completedNCT00015925
What this trial is testing

MS-275 in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaMultiple Myeloma and Plasma Cell NeoplasmMyelodysplastic Syndromes+1 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)Ended earlyNCT01234532
What this trial is testing

Entinostat and Anastrozole in Treating Postmenopausal Women With TNBC That Can Be Removed by Surgery

Who this might be right for
Estrogen Receptor-negative Breast CancerHER2-negative Breast CancerProgesterone Receptor-negative Breast Cancer+4 more
University of Maryland, Baltimore 5
Testing effectiveness (Phase 2)Ended earlyNCT03024437
What this trial is testing

Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell Carcinoma

Who this might be right for
Metastatic CancerRenal Cancer
Roberto Pili 31
Large-scale testing (Phase 3)UnknownNCT03538171
What this trial is testing

Ph3 Study of Exemestane With or Without Entinostat in Chinese Patients With Hormone Receptor-Positive, Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Advanced Breast Cancer
Taizhou EOC Pharma Co., Ltd. 375
Early research (Phase 1)Ended earlyNCT01159301
What this trial is testing

Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+16 more
National Cancer Institute (NCI) 44
Early research (Phase 1)Study completedNCT02909452
What this trial is testing

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Who this might be right for
NeoplasmsNeoplasms, Glandular and EpithelialNeoplasms by Histologic Type+11 more
Syndax Pharmaceuticals 30
Testing effectiveness (Phase 2)Ended earlyNCT00866333
What this trial is testing

Multi-Center Study of Entinostat (SNDX-275) in Patient With Relapsed or Refractory Hodgkin's Lymphoma

Who this might be right for
Hodgkin's Lymphoma
Syndax Pharmaceuticals 49
Early research (Phase 1)Study completedNCT00098891
What this trial is testing

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

Who this might be right for
Adult Grade III Lymphomatoid GranulomatosisAnaplastic Large Cell LymphomaAngioimmunoblastic T-cell Lymphoma+41 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Study completedNCT03765229
What this trial is testing

An Exploratory Study of Pembrolizumab Plus Entinostat in Non-Inflamed Stage III/IV Melanoma

Who this might be right for
Melanoma
UNC Lineberger Comprehensive Cancer Center 11
Testing effectiveness (Phase 2)UnknownNCT01305499
What this trial is testing

A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Hetty Carraway 52
Testing effectiveness (Phase 2)Study completedNCT00676663
What this trial is testing

Study to Evaluate Exemestane With and Without Entinostat (SNDX-275) in Treatment of Postmenopausal Women With Advanced Breast Cancer

Who this might be right for
Breast CancerEstrogen Receptor-Positive Breast CancerBreast Cancer, Estrogen Receptor-Positive+1 more
Syndax Pharmaceuticals 130
Testing effectiveness (Phase 2)Ended earlyNCT01935947
What this trial is testing

Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

Who this might be right for
Recurrent Non-Small Cell Lung CarcinomaStage IIIA Non-Small Cell Lung CancerStage IIIB Non-Small Cell Lung Cancer+1 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Active Not RecruitingNCT03978624
What this trial is testing

Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer

Who this might be right for
Bladder Cancer
UNC Lineberger Comprehensive Cancer Center 20
Testing effectiveness (Phase 2)Study completedNCT00602030
What this trial is testing

Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC

Who this might be right for
Non-Small-Cell Lung CarcinomaCarcinoma, Non-Small Cell Lung
Syndax Pharmaceuticals 141
Testing effectiveness (Phase 2)WithdrawnNCT05898828
What this trial is testing

Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer

Who this might be right for
NeoplasmsEsophageal NeoplasmsEsophagus Neoplasm+3 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT01132573
What this trial is testing

Entinostat and Clofarabine in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Poor-Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineagePhiladelphia Chromosome Negative Adult Precursor Acute Lymphoblastic LeukemiaRecurrent Adult Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Study completedNCT02915523
What this trial is testing

Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer

Who this might be right for
Epithelial Ovarian CancerPeritoneal CancerFallopian Tube Cancer
Syndax Pharmaceuticals 140
Early research (Phase 1)Study completedNCT03187015
What this trial is testing

Examine the Effects of Entinostat on Midazolam in Healthy Adult Subjects

Who this might be right for
Drug InteractionHealthy Volunteer
Syndax Pharmaceuticals 26
Early research (Phase 1)Study completedNCT03473639
What this trial is testing

A Pilot Study of the Combination of Entinostat With Capecitabine in High Risk Breast Cancer After Neo-adjuvant Therapy

Who this might be right for
Metastatic Breast CancerBreast Cancer
University of Virginia 13
Testing effectiveness (Phase 2)Ended earlyNCT03552380
What this trial is testing

Study of Entinostat With Nivolumab Plus Ipilimumab in Previously Treated Renal Cell Carcinoma

Who this might be right for
Renal Cell Carcinoma
Roberto Pili 12
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