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Results for “Entinostat”

71 trials

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Showing 20 of 71 results

Testing effectiveness (Phase 2)Ended earlyNCT01383447
What this trial is testing

Entinostat And Imatinib Mesylate In Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Who this might be right for
Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic LeukemiaRecurrent Adult Acute Lymphoblastic Leukemia
National Cancer Institute (NCI) 2
Testing effectiveness (Phase 2)Ended earlyNCT03024437
What this trial is testing

Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell Carcinoma

Who this might be right for
Metastatic CancerRenal Cancer
Roberto Pili 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT01038778
What this trial is testing

Entinostat in Combination With Aldesleukin in Treating Patients With Metastatic Kidney Cancer

Who this might be right for
Clear Cell Renal Cell CarcinomaMetastatic Kidney CarcinomaStage III Renal Cell Cancer AJCC v7+1 more
National Cancer Institute (NCI) 47
Early research (Phase 1)Study completedNCT02922933
What this trial is testing

Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult Subjects

Who this might be right for
VolunteersHealthy VolunteersHuman Volunteers+1 more
Syndax Pharmaceuticals 66
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07235618
What this trial is testing

Entinostat in Combination With Fulvestrant for the Treatment of Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Locally Advanced or Metastatic Breast Cancer
Sun Yat-sen University 50
Early research (Phase 1)Study completedNCT00015925
What this trial is testing

MS-275 in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaMultiple Myeloma and Plasma Cell NeoplasmMyelodysplastic Syndromes+1 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Early research (Phase 1)WithdrawnNCT03925428
What this trial is testing

Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmAnn Arbor Stage III B-Cell Non-Hodgkin Lymphoma+14 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT07330544
What this trial is testing

A Phase II Clinical Study Evaluating Entinostat With or Without Anlotinib + Fulvestrant for the Treatment of Hormone Receptor (HR) -Positive, Human Epidermal Growth Factor Receptor-2 (HER-2) -Negative Advanced Breast Cancer That Relapsed or Progressed After Endocrine Therapy

Who this might be right for
Breast Cancer
Zhejiang Cancer Hospital 118
Early research (Phase 1)Study completedNCT04631029
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaMalignant Solid NeoplasmMetastatic Malignant Neoplasm in the Brain
National Cancer Institute (NCI) 3
Early research (Phase 1)WithdrawnNCT03760614
What this trial is testing

Entinostat and FOLFOX in Subjects With Pancreatic Adenocarcinoma

Who this might be right for
Pancreas Cancer
Abramson Cancer Center at Penn Medicine
Testing effectiveness (Phase 2)Study completedNCT02915523
What this trial is testing

Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer

Who this might be right for
Epithelial Ovarian CancerPeritoneal CancerFallopian Tube Cancer
Syndax Pharmaceuticals 140
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07261592
What this trial is testing

Entinostat & Chemotherapy for Locally Advanced or Metastatic Bladder Cancer

Who this might be right for
Bladder CancerHistone Deacetylase InhibitorEntinostat+1 more
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 29
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07441486
What this trial is testing

A Single-arm, Prospective, Phase II Clinical Study of the Combination of Entinostat and Oral Paclitaxel in the Treatment of HR+HER2- Advanced Breast Cancer

Who this might be right for
Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 50
Testing effectiveness (Phase 2)Looking for participantsNCT07492394
What this trial is testing

Dalpiciclib With or Without Entinostat and Letrozole in HR+/HER2- Early Breast Cancer

Who this might be right for
Breast Cancer
Hebei Medical University Fourth Hospital 60
Early research (Phase 1)Study completedNCT03187015
What this trial is testing

Examine the Effects of Entinostat on Midazolam in Healthy Adult Subjects

Who this might be right for
Drug InteractionHealthy Volunteer
Syndax Pharmaceuticals 26
Early research (Phase 1)Study completedNCT02820961
What this trial is testing

Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer

Who this might be right for
Breast CancerEstrogen Receptor Positive Breast Cancer
Syndax Pharmaceuticals 61
Early research (Phase 1)Active Not RecruitingNCT02453620
What this trial is testing

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Breast Adenocarcinoma+2 more
National Cancer Institute (NCI) 57
Testing effectiveness (Phase 2)Study completedNCT00602030
What this trial is testing

Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC

Who this might be right for
Non-Small-Cell Lung CarcinomaCarcinoma, Non-Small Cell Lung
Syndax Pharmaceuticals 141
Early research (Phase 1)Ended earlyNCT01159301
What this trial is testing

Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+16 more
National Cancer Institute (NCI) 44
Testing effectiveness (Phase 2)Ended earlyNCT03211988
What this trial is testing

Entinostat Neuroendocrine (NE) Tumor

Who this might be right for
Neuroendocrine Tumors
Antonio Fojo 5
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