Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Entinostat”

69 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 69 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04708470
What this trial is testing

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Who this might be right for
Oropharyngeal CancerNeck CancerHuman Papillomavirus+7 more
National Cancer Institute (NCI) 55
Testing effectiveness (Phase 2)Study completedNCT03765229
What this trial is testing

An Exploratory Study of Pembrolizumab Plus Entinostat in Non-Inflamed Stage III/IV Melanoma

Who this might be right for
Melanoma
UNC Lineberger Comprehensive Cancer Center 11
Very early researchEnded earlyNCT03361800
What this trial is testing

Window of Opportunity Trial of Entinostat in Patients With Newly Diagnosed Stage I-IIIC,TNBC

Who this might be right for
Breast CancerInvasive Breast CancerER-Negative PR-Negative HER2-Negative Breast Cancer
UNC Lineberger Comprehensive Cancer Center 5
Large-scale testing (Phase 3)Active Not RecruitingNCT02115282
What this trial is testing

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Breast Adenocarcinoma+4 more
National Cancer Institute (NCI) 608
Testing effectiveness (Phase 2)Study completedNCT01928576
What this trial is testing

Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.

Who this might be right for
Non-Small Cell Lung CancerEpigenetic Therapy
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 143
Early research (Phase 1)Study completedNCT00015925
What this trial is testing

MS-275 in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaMultiple Myeloma and Plasma Cell NeoplasmMyelodysplastic Syndromes+1 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)Active Not RecruitingNCT01305499
What this trial is testing

A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Hetty Carraway 52
Very early researchStudy completedNCT03018249
What this trial is testing

Medroxyprogesterone Acetate With or Without Entinostat Before Surgery in Treating Patients With Endometrioid Endometrial Cancer

Who this might be right for
FIGO Grade 1 Endometrial Endometrioid AdenocarcinomaFIGO Grade 2 Endometrial Endometrioid AdenocarcinomaFIGO Grade 3 Endometrial Endometrioid Adenocarcinoma
National Cancer Institute (NCI) 50
Early research (Phase 1)Study completedNCT02820961
What this trial is testing

Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer

Who this might be right for
Breast CancerEstrogen Receptor Positive Breast Cancer
Syndax Pharmaceuticals 61
Testing effectiveness (Phase 2)Study completedNCT00828854
What this trial is testing

Study of the Effect of the Addition of SNDX-275 (Entinostat) to Continued Aromatase Inhibitor (AI) Therapy in Postmenopausal Women With ER+ Breast Cancer Whose Disease is Progressing

Who this might be right for
ER+ Breast Cancer
Syndax Pharmaceuticals 27
Early research (Phase 1)Active Not RecruitingNCT02453620
What this trial is testing

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Breast Adenocarcinoma+2 more
National Cancer Institute (NCI) 57
Early research (Phase 1)Ended earlyNCT01886573
What this trial is testing

Azacitidine and Entinostat in Treating Patients With Newly Diagnosed Stage IA-IIIA Non-Small Lung Cancer Undergoing Surgery

Who this might be right for
Stage IA Non-Small Cell Lung CarcinomaStage IB Non-Small Cell Lung CarcinomaStage IIA Non-Small Cell Lung Carcinoma+2 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Study completedNCT02915523
What this trial is testing

Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer

Who this might be right for
Epithelial Ovarian CancerPeritoneal CancerFallopian Tube Cancer
Syndax Pharmaceuticals 140
Early research (Phase 1)Ended earlyNCT04296942
What this trial is testing

BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)

Who this might be right for
Breast CancerTriple Negative Breast CancerHER2+ Breast Cancer+2 more
National Cancer Institute (NCI) 1
Early research (Phase 1)Ended earlyNCT03924245
What this trial is testing

Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers

Who this might be right for
Fallopian Tube CancerFallopian Tube CarcinosarcomaFallopian Tube Clear Cell Adenocarcinoma+10 more
Vanderbilt-Ingram Cancer Center 3
Testing effectiveness (Phase 2)Study completedNCT03250273
What this trial is testing

A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma

Who this might be right for
Metastatic CholangiocarcinomaCholangiocarcinomaPancreatic Cancer+3 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 44
Testing effectiveness (Phase 2)Study completedNCT00602030
What this trial is testing

Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC

Who this might be right for
Non-Small-Cell Lung CarcinomaCarcinoma, Non-Small Cell Lung
Syndax Pharmaceuticals 141
Testing effectiveness (Phase 2)Study completedNCT00185302
What this trial is testing

Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma

Who this might be right for
Melanoma
Bayer 28
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Early research (Phase 1)Study completedNCT02922946
What this trial is testing

Study to Determine the Effect of the Timing of a Meal on the Pharmacokinetics of Entinostat

Who this might be right for
VolunteersHealthy VolunteersHuman Volunteers+1 more
Syndax Pharmaceuticals 47
Load More Results