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Results for “Enzyme Inhibitors”

235 trials

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Showing 20 of 235 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04699188
What this trial is testing

Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

Who this might be right for
KRAS G12C Mutant Solid TumorsCarcinoma, Non-Small-Cell LungCarcinoma, Colorectal+7 more
Novartis Pharmaceuticals 344
Testing effectiveness (Phase 2)Study completedNCT02220803
What this trial is testing

A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction

Who this might be right for
Obstructive Sleep ApneaSleep-Disordered BreathingBlood Pressure+1 more
Göteborg University 13
Large-scale testing (Phase 3)Looking for participantsNCT07555483
What this trial is testing

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Grifols Therapeutics LLC 40
Not applicableUnknownNCT04364893
What this trial is testing

Angiotensin Receptor Blockers and Angiotensin-converting Enzyme Inhibitors and Adverse Outcomes in Patients With COVID19

Who this might be right for
Corona Virus InfectionCOVID-19
D'Or Institute for Research and Education 700
Post-approval studies (Phase 4)Study completedNCT01201811
What this trial is testing

Study of Azacitidine in Adult Taiwanese Subjects With Higher-Risk Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic Syndromes
Celgene 44
Post-approval studies (Phase 4)Study completedNCT01575652
What this trial is testing

Effects of Aceis on Peritoneal Protein Loss and Solute Transport in pd Patients

Who this might be right for
Disorders Associated With Peritoneal Dialysis
Turkish Nephrology Association 43
Large-scale testing (Phase 3)UnknownNCT01956786
What this trial is testing

Efficacy of Amlodipine-Folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine

Who this might be right for
Essential Hypertension
Shenzhen Ausa Pharmed Co.,Ltd 540
Not applicableStudy completedNCT04351581
What this trial is testing

Effects of Discontinuing Renin-angiotensin System Inhibitors in Patients With and Without COVID-19

Who this might be right for
Covid-19
University Hospital, Gentofte, Copenhagen 78
Post-approval studies (Phase 4)Ended earlyNCT03686696
What this trial is testing

Randomized Evaluation of Beta Blocker and ACEI/ARB Treatment in MINOCA Patients - MINOCA-BAT

Who this might be right for
Myocardial Infarction With Non-obstructive Coronary Arteries
Uppsala University 198
Large-scale testing (Phase 3)Ended earlyNCT00736294
What this trial is testing

Prevention of Atrial Fibrillation by Inhibition Conversion Enzyme (ICE) After Radiofrequency Ablation of Atrial Flutter

Who this might be right for
Atrial FibrillationAtrial Flutter
Centre Hospitalier Universitaire de Saint Etienne 198
Not applicableStudy completedNCT01071642
What this trial is testing

The Influence of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Renal Function in Patients Undergoing Non-emergent Coronary Angiography

Who this might be right for
Blood Pressure
Soroka University Medical Center 100
Large-scale testing (Phase 3)WithdrawnNCT05259137
What this trial is testing

Intra-lesional ACE Inhibitor for Treatment of Hypertrophic Scars

Who this might be right for
Hypertrophic Scar
Nova Scotia Health Authority
Large-scale testing (Phase 3)Study completedNCT01919801
What this trial is testing

Blinded Safety & Efficacy Placebo Controlled Study of Icatibant for Angiotensin Converting Enzyme Inhibitor Induced Angioedema

Who this might be right for
Angiotensin Converting Enzyme Inhibitor Induced Angioedema
Shire 118
Not applicableUnknownNCT04326933
What this trial is testing

Effects of Tyrosine Kinase Inhibitors on Liver Enzymes and Electrolytes

Who this might be right for
Patients Diagnosed as Chronic Meyloid Leukemia
Assiut University 40
Not applicableStudy completedNCT01105299
What this trial is testing

Bioequivalence Study of Anastrozole 1 mg Tablet

Who this might be right for
Healthy
Asan Medical Center 24
Large-scale testing (Phase 3)Ended earlyNCT00555217
What this trial is testing

VA NEPHRON-D: Diabetes iN Nephropathy Study

Who this might be right for
Kidney DiseaseNephropathyType 2 Diabetes
US Department of Veterans Affairs 1,448
Not applicableActive Not RecruitingNCT06515678
What this trial is testing

Impact of Antihypertensive Therapy on Recurrence Risk of Ovarian Cancer for Bevacizumab-associated Hypertension

Who this might be right for
Ovarian CancerAntiangiogenic-Associated HypertensionAdjuvant Bevacizumab+1 more
Groupe Hospitalier Pitie-Salpetriere 9,464
Large-scale testing (Phase 3)Study completedNCT04334148
What this trial is testing

Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine

Who this might be right for
COVID-19
Adrian Hernandez 1,360
Very early researchUnknownNCT04340349
What this trial is testing

Low-dose Hydroxychloroquine and Bromhexine: a Novel Regimen for COVID-19 Prophylaxis in Healthcare Professionals

Who this might be right for
HydroxychloroquineAntimalarialsEnzyme Inhibitors+1 more
Instituto Nacional de Rehabilitacion 214
Not applicableStudy completedNCT03188601
What this trial is testing

Α1-antitrypsin (AAT) Levels and Functions in Allogeneic Bone Marrow Transplantation and Throughout Progression Into GVHD

Who this might be right for
GVHDBone Marrow Transplant FailureAlpha 1-Antitrypsin
Rambam Health Care Campus 27
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