Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Epilepsy, Primary Generalized Tonic-Clonic Seizures”

30 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 30 results

Not applicableStudy completedNCT05147571
What this trial is testing

RNS System NAUTILUS Study

Who this might be right for
EpilepsyIdiopathic Generalized EpilepsyGeneralized Tonic Clonic Seizure
NeuroPace 100
Large-scale testing (Phase 3)Study completedNCT01393743
What this trial is testing

A Efficacy and Safety Study of Adjunctive Perampanel in Primary Generalized Tonic Clonic Seizures

Who this might be right for
Seizure Disorder Generalized Tonic Clonic
Eisai Inc. 163
Large-scale testing (Phase 3)Enrolling By InvitationNCT07287163
What this trial is testing

Clinical Trial of Vormatrigine in Adult Patients With Epilepsy

Who this might be right for
Epilepsy, Tonic-ClonicFocal SeizurePrimary Generalized Seizure
Praxis Precision Medicines 700
Large-scale testing (Phase 3)Ended earlyNCT00692003
What this trial is testing

Adjunctive Zonisamide in Primary Generalised Tonic Clonic Seizures

Who this might be right for
Epilepsy
Eisai Limited 21
Testing effectiveness (Phase 2)Study completedNCT00210652
What this trial is testing

An Open-Label Extension Study to Evaluate the Safety and Effectiveness of RWJ 333369 in Patients With Epilepsy

Who this might be right for
EpilepsyEpilepsies, Partial
SK Life Science, Inc. 47
Large-scale testing (Phase 3)Study completedNCT02408549
What this trial is testing

Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic Seizures

Who this might be right for
Epilepsy
UCB BIOSCIENCES, Inc. 239
Post-approval studies (Phase 4)Study completedNCT00043901
What this trial is testing

Treatment Of Primary Generalized Tonic-Clonic Seizures With An Investigational New Drug

Who this might be right for
Epilepsy, Tonic-Clonic
GlaxoSmithKline 141
Large-scale testing (Phase 3)Looking for participantsNCT06579573
What this trial is testing

ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures.

Who this might be right for
Epilepsy, Generalized
Ono Pharmaceutical Co., Ltd. 15
Large-scale testing (Phase 3)Study completedNCT00236704
What this trial is testing

The Efficacy and Safety of Topiramate as "Add on" Treatment in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Who this might be right for
EpilepsySeizures
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 80
Testing effectiveness (Phase 2)Looking for participantsNCT06908356
What this trial is testing

An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures

Who this might be right for
Focal Onset SeizurePrimary Generalized Epilepsy
Praxis Precision Medicines 50
Large-scale testing (Phase 3)Study completedNCT00160550
What this trial is testing

Study to Evaluate the Safety and Efficacy of Levetiracetam in Patients Suffering From Idiopathic Generalized Epilepsy With Primary Generalized Tonic-clonic Seizures

Who this might be right for
Generalized Convulsive Epilepsy
UCB Pharma 154
Large-scale testing (Phase 3)Study completedNCT01463306
What this trial is testing

A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures

Who this might be right for
Epilepsy, Partial SeizuresEpilepsy, Primary Generalized Tonic-Clonic Seizures
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 605
Not applicableNo Longer AvailableNCT02307578
What this trial is testing

An Extended Access Program (EAP) for Perampanel

Who this might be right for
Primary Generalized Tonic-Clonic or Partial Onset SeizuresLennox Gastaut Syndrome
Eisai Inc.
Testing effectiveness (Phase 2)Study completedNCT03754582
What this trial is testing

Intravenous Perampanel in Japanese Participants With Epilepsy

Who this might be right for
EpilepsySeizures
Eisai Co., Ltd. 21
Testing effectiveness (Phase 2)Study completedNCT01118949
What this trial is testing

Open-Label Study to Assess Lacosamide Safety as Add-on Therapy for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy

Who this might be right for
Epilepsy
UCB BIOSCIENCES, Inc. 49
Large-scale testing (Phase 3)Study completedNCT01747915
What this trial is testing

A Safety, Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e., Grand Mal) Seizures.

Who this might be right for
Generalized Tonic Clonic Seizures
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 219
Large-scale testing (Phase 3)Looking for participantsNCT05667142
What this trial is testing

Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Who this might be right for
Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc. 160
Large-scale testing (Phase 3)Enrolling By InvitationNCT03961568
What this trial is testing

Cenobamate Open-Label Extension Study for YKP3089C025

Who this might be right for
Primary Generalized Tonic Clonic Seizures in the Setting of Idiopathic Generalized Epilepsy
SK Life Science, Inc. 145
Large-scale testing (Phase 3)Study completedNCT00104416
What this trial is testing

Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) Seizures

Who this might be right for
Epilepsy, Tonic-Clonic
GlaxoSmithKline 153
Large-scale testing (Phase 3)Study completedNCT00236886
What this trial is testing

Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients

Who this might be right for
EpilepsyEpilepsies, PartialEpilepsy, Generalized+1 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 49
Load More Results