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Results for “Epileptic Encephalopathy”

100 trials

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Showing 20 of 100 results

Large-scale testing (Phase 3)Looking for participantsNCT07010471
What this trial is testing

A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine

Who this might be right for
Developmental and Epileptic Encephalopathy 1
Praxis Precision Medicines 160
Not applicableEnded earlyNCT03955432
What this trial is testing

Long-term Cardiac Monitoring in Epilepsy

Who this might be right for
Focal EpilepsyIntractable EpilepsyEpileptic Encephalopathy+3 more
Northwell Health 7
Large-scale testing (Phase 3)Looking for participantsNCT07019922
What this trial is testing

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

Who this might be right for
Epileptic EncephalopathySCN2A Encephalopathy
Praxis Precision Medicines 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07102524
What this trial is testing

Intrathecal Gene Therapy For SLC13A5 Citrate Transporter Disorder

Who this might be right for
SLC13A5 Citrate Transporter Disorder
TESS Research Foundation 2
Large-scale testing (Phase 3)Study completedNCT03936777
What this trial is testing

Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome

Who this might be right for
Dravet SyndromeLennox Gastaut SyndromeEpileptic Encephalopathy
Zogenix, Inc. 412
Testing effectiveness (Phase 2)Looking for participantsNCT07363603
What this trial is testing

Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders.

Who this might be right for
GNAO1EpilepsyHyperkinesis
Pirogov Russian National Research Medical University 5
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Testing effectiveness (Phase 2)Study completedNCT05626634
What this trial is testing

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome
Longboard Pharmaceuticals 41
Not applicableUnknownNCT03934268
What this trial is testing

A Cohort Study on the Prognosis of Neonatal KCNQ2 Gene-associated Epileptic Encephalopathy

Who this might be right for
SeizuresSeizure DisorderSeizure Newborn+5 more
Children's Hospital of Fudan University 100
Not applicableLooking for participantsNCT05722990
What this trial is testing

Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam

Who this might be right for
Whole Exome SequencingEpileptic Encephalopathy
Number 2 Children's Hospital, Ho Chi Minh City 150
Not applicableLooking for participantsNCT06855901
What this trial is testing

Home Ultra-long Term EEG Monitoring for Rare Epilepsies and Developmental and Epileptic Encephalopathies

Who this might be right for
EpilepsiesEpilepsies, FocalEpileptic Encephalopathy
Azienda Ospedaliero-Universitaria di Modena 30
Testing effectiveness (Phase 2)Study completedNCT03650452
What this trial is testing

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies

Who this might be right for
EpilepsyDravet SyndromeLennox-Gastaut Syndrome
Takeda 141
Large-scale testing (Phase 3)Ended earlyNCT04639310
What this trial is testing

XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy

Who this might be right for
EpilepsyEpilepsy in ChildrenEpilepsy; Seizure+5 more
Xenon Pharmaceuticals Inc. 8
Not applicableStudy completedNCT05407727
What this trial is testing

A Prospective, Remote Observational Study in Pediatric Participants With Early-Onset SCN2A-Developmental and Epileptic Encephalopathy

Who this might be right for
SCN2A-DEEEpilepsy
Praxis Precision Medicines 5
Testing effectiveness (Phase 2)Ended earlyNCT05301894
What this trial is testing

Extension Study to Evaluate NBI-827104 in Pediatric Participants With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Who this might be right for
Epileptic EncephalopathyContinuous Spike and Wave During Sleep
Neurocrine Biosciences 19
Testing effectiveness (Phase 2)WithdrawnNCT02968966
What this trial is testing

Pathophysiology Based Therapy of Early Onset Epileptic Encephalopathies

Who this might be right for
Seizure, Epileptic
University Hospital Tuebingen
Not applicableLooking for participantsNCT01858285
What this trial is testing

Genetics of Epilepsy and Related Disorders

Who this might be right for
EpilepsyEpileptic Encephalopathy
Boston Children's Hospital 5,000
Large-scale testing (Phase 3)Study completedNCT03572933
What this trial is testing

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency Disorder
Marinus Pharmaceuticals 101
Not applicableStudy completedNCT02960347
What this trial is testing

Examining the Efficacy of tDCS in the Attenuation of Epileptic Paroxysmal Discharges and Clinical Seizures

Who this might be right for
Ohtahara Syndrome
Herzog Hospital 1
Not applicableLooking for participantsNCT06958341
What this trial is testing

Neuroimmunology Registry and Biobank

Who this might be right for
EncephalopathyPsychosisImpaired Consciousness+5 more
Charite University, Berlin, Germany 300
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