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Results for “Epileptic Encephalopathy”

105 trials

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Showing 20 of 105 results

Large-scale testing (Phase 3)Study completedNCT03936777
What this trial is testing

Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome

Who this might be right for
Dravet SyndromeLennox Gastaut SyndromeEpileptic Encephalopathy
Zogenix, Inc. 412
Large-scale testing (Phase 3)Ended earlyNCT04639310
What this trial is testing

XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy

Who this might be right for
EpilepsyEpilepsy in ChildrenEpilepsy; Seizure+5 more
Xenon Pharmaceuticals Inc. 8
Large-scale testing (Phase 3)Active Not RecruitingNCT06660394
What this trial is testing

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Who this might be right for
Dravet Syndrome
Longboard Pharmaceuticals 96
Testing effectiveness (Phase 2)Study completedNCT04625101
What this trial is testing

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Who this might be right for
Epileptic EncephalopathyContinuous Spike and Wave During Sleep
Neurocrine Biosciences 24
Large-scale testing (Phase 3)Not Yet RecruitingNCT07723976
What this trial is testing

Evaluate the Safety and Efficacy of CBD-OS in Participants With DEE

Who this might be right for
Developmental and Epileptic Encephalopathy (DEE)
Jazz Pharmaceuticals 120
Not applicableWithdrawnNCT05462054
What this trial is testing

Natural History Study in Pediatric Patients with STXBP1 Encephalopathy with Epilepsy

Who this might be right for
STXBP1 Encephalopathy with Epilepsy
Capsida Biotherapeutics, Inc.
Not applicableLooking for participantsNCT05673915
What this trial is testing

Study of Transcranial Direct Current Stimulation to Treat Epilepsy

Who this might be right for
Focal EpilepsyGeneralized Onset EpilepsySleep-related Epileptic Encephalopathy
Mayo Clinic 30
Not applicableUnknownNCT04054453
What this trial is testing

Prevention of Epilepsy by Reducing Neonatal Encephalopathy

Who this might be right for
Neonatal EncephalopathyEpilepsyNewborn Morbidity
Thayyil, Sudhin 2,000
Not applicableEnrolling By InvitationNCT07264166
What this trial is testing

Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)

Who this might be right for
Hypoxic Brain DamageHypoxic Ischaemic Encephalopathy (HIE)Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest+6 more
Healing Hope International 25
Large-scale testing (Phase 3)Study completedNCT03572933
What this trial is testing

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency Disorder
Marinus Pharmaceuticals 101
Not applicableStudy completedNCT03652246
What this trial is testing

Evaluation of the Diagnostic Contribution of High-throughput Exome Sequencing for Patients With Convulsive Encephalopathy of Unknown Etiology: Pilot Study to Improve Genetic Counselling

Who this might be right for
Epileptic Encephalopathy of Unindentified Genetic Origin
Centre Hospitalier Universitaire Dijon 15
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)WithdrawnNCT02968966
What this trial is testing

Pathophysiology Based Therapy of Early Onset Epileptic Encephalopathies

Who this might be right for
Seizure, Epileptic
University Hospital Tuebingen
Not applicableActive Not RecruitingNCT06500260
What this trial is testing

CNKSR2 Natural History Study

Who this might be right for
Developmental DysphasiaEpileptic Encephalopathy, Childhood-OnsetX-Linked Intellectual Disability
University of California, San Francisco 20
Testing effectiveness (Phase 2)Looking for participantsNCT07102524
What this trial is testing

Intrathecal Gene Therapy For SLC13A5 Citrate Transporter Disorder

Who this might be right for
SLC13A5 Citrate Transporter Disorder
TESS Research Foundation 8
Not applicableStudy completedNCT04924153
What this trial is testing

A Natural History Study of Participants With Potassium Sodium-Activated Channel Subfamily T Member 1 (KCNT1)-Related Epilepsy

Who this might be right for
KCNT1-Related Epilepsy
Biogen 35
Large-scale testing (Phase 3)Active Not RecruitingNCT05818553
What this trial is testing

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

Who this might be right for
SCN2A EncephalopathySCN8A Encephalopathy
Praxis Precision Medicines 77
Post-approval studies (Phase 4)WithdrawnNCT01370486
What this trial is testing

Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects

Who this might be right for
Lennox-Gastaut Syndrome
Institution de Lavigny
Testing effectiveness (Phase 2)Looking for participantsNCT06401538
What this trial is testing

BMB-101 in Absence Epilepsy and DEE

Who this might be right for
Absence EpilepsyJeavons SyndromeDravet Syndrome+1 more
Bright Minds Biosciences Pty Ltd 20
Not applicableLooking for participantsNCT06278428
What this trial is testing

Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age

Who this might be right for
Epilepsy; SeizureChild DevelopmentGene Abnormality+1 more
Number 2 Children's Hospital, Ho Chi Minh City 50
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