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Results for “Epileptic Encephalopathy”

102 trials

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Showing 20 of 102 results

Not applicableLooking for participantsNCT06555965
What this trial is testing

STXBP1 and SYNGAP1 Related Disorders Natural History Study

Who this might be right for
Genetic DiseaseSTXBP1 Encephalopathy With EpilepsySYNGAP1-Related Intellectual Disability
Children's Hospital of Philadelphia 600
Testing effectiveness (Phase 2)Looking for participantsNCT07227857
What this trial is testing

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Who this might be right for
Epileptic Encephalopathy
Institut de Recherches Internationales Servier 20
Testing effectiveness (Phase 2)UnknownNCT03944447
What this trial is testing

Outcomes Mandate National Integration With Cannabis as Medicine

Who this might be right for
Chronic PainChronic Pain SyndromeChronic Pain Due to Injury+30 more
OMNI Medical Services, LLC 200,000
Not applicableEnded earlyNCT04537832
What this trial is testing

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 58
Large-scale testing (Phase 3)Study completedNCT02682927
What this trial is testing

A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) in Children and Young Adults With Dravet Syndrome

Who this might be right for
Dravet SyndromeSeizure Disorder
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc. 262
Post-approval studies (Phase 4)Study completedNCT03779672
What this trial is testing

Memantine for Epileptic Encephalopathy

Who this might be right for
Epileptic Encephalopathy, Childhood-Onset
Kenneth Myers, MD 30
Not applicableUnknownNCT04054453
What this trial is testing

Prevention of Epilepsy by Reducing Neonatal Encephalopathy

Who this might be right for
Neonatal EncephalopathyEpilepsyNewborn Morbidity
Thayyil, Sudhin 2,000
Not applicableLooking for participantsNCT06092346
What this trial is testing

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Who this might be right for
AMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more
National Human Genome Research Institute (NHGRI)
Testing effectiveness (Phase 2)Study completedNCT04625101
What this trial is testing

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Who this might be right for
Epileptic EncephalopathyContinuous Spike and Wave During Sleep
Neurocrine Biosciences 24
Large-scale testing (Phase 3)Looking for participantsNCT07019922
What this trial is testing

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

Who this might be right for
Epileptic EncephalopathySCN2A Encephalopathy
Praxis Precision Medicines 50
Not applicableNot Yet RecruitingNCT06356233
What this trial is testing

Phenotyping and Identification of Biological Markers in STXBP1 Encephalopathy

Who this might be right for
STXBP1 Encephalopathy With Epilepsy
Fundación Iniciativa para las Neurociencias (FINCE) 10
Not applicableStudy completedNCT02056236
What this trial is testing

TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation

Who this might be right for
Cardiac ArrestAnoxic EncephalopathyStatus Epilepticus
University of Twente 172
Large-scale testing (Phase 3)Study completedNCT03936777
What this trial is testing

Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome

Who this might be right for
Dravet SyndromeLennox Gastaut SyndromeEpileptic Encephalopathy
Zogenix, Inc. 412
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07102524
What this trial is testing

Intrathecal Gene Therapy For SLC13A5 Citrate Transporter Disorder

Who this might be right for
SLC13A5 Citrate Transporter Disorder
TESS Research Foundation 2
Testing effectiveness (Phase 2)Looking for participantsNCT07363603
What this trial is testing

Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders.

Who this might be right for
GNAO1EpilepsyHyperkinesis
Pirogov Russian National Research Medical University 5
Not applicableLooking for participantsNCT06625112
What this trial is testing

A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders

Who this might be right for
STXBP1 Encephalopathy With Epilepsy
European STXBP1 Consortium 120
Large-scale testing (Phase 3)Looking for participantsNCT06719141
What this trial is testing

Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Who this might be right for
Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals 320
Not applicableEnrolling By InvitationNCT07264166
What this trial is testing

Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)

Who this might be right for
Hypoxic Brain DamageHypoxic Ischaemic Encephalopathy (HIE)Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest+6 more
Healing Hope International 25
Not applicableLooking for participantsNCT01858285
What this trial is testing

Genetics of Epilepsy and Related Disorders

Who this might be right for
EpilepsyEpileptic Encephalopathy
Boston Children's Hospital 5,000
Not applicableStudy completedNCT04924153
What this trial is testing

A Natural History Study of Participants With Potassium Sodium-Activated Channel Subfamily T Member 1 (KCNT1)-Related Epilepsy

Who this might be right for
KCNT1-Related Epilepsy
Biogen 35
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