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Results for “Ertugliflozin”

39 trials

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Showing 20 of 39 results

Post-approval studies (Phase 4)Study completedNCT04027530
What this trial is testing

Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study.

Who this might be right for
Type 2 Diabetes MellitusDiabetic Kidney DiseaseDiabetic Nephropathy+4 more
Amsterdam UMC, location VUmc 40
Post-approval studies (Phase 4)Study completedNCT05727579
What this trial is testing

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study

Who this might be right for
Diabetes MellitusDiabetic Kidney DiseaseHypertension
Amsterdam UMC, location VUmc 41
Large-scale testing (Phase 3)Study completedNCT04029480
What this trial is testing

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 166
Large-scale testing (Phase 3)Study completedNCT01986881
What this trial is testing

Cardiovascular Outcomes Following Ertugliflozin Treatment in Type 2 Diabetes Mellitus Participants With Vascular Disease, The VERTIS CV Study (MK-8835-004)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 8,246
Early research (Phase 1)Study completedNCT01054300
What this trial is testing

Effects of Once and Twice Daily Dosing Regimen of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-040)

Who this might be right for
Diabetes Mellitus, Type 2Adult
Merck Sharp & Dohme LLC 52
Large-scale testing (Phase 3)Study completedNCT02099110
What this trial is testing

Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 1,233
Large-scale testing (Phase 3)Study completedNCT02033889
What this trial is testing

Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 621
Early research (Phase 1)Study completedNCT01127308
What this trial is testing

A Radiolabeled Mass Balance Study of [14C]-Ertugliflozin (PF04971729, MK-8835) In Healthy Male Participants (MK-8835-038)

Who this might be right for
Type 2 Diabetes Mellitus (T2DM)
Merck Sharp & Dohme LLC 6
Not applicableStudy completedNCT05556291
What this trial is testing

Combination of Ertugliflozin And Sitagliptin Efficacy, Safety & Tolerability (CEASE Diabetes) Study

Who this might be right for
EfficacySafetyTolerability
Getz Pharma 190
Large-scale testing (Phase 3)Study completedNCT01999218
What this trial is testing

Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 1,326
Early research (Phase 1)Study completedNCT01948986
What this trial is testing

Effect of Renal Impairment on the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Ertugliflozin in Participants With Type 2 Diabetes Mellitus (MK-8835-009)

Who this might be right for
Renal ImpairmentType 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 36
Early research (Phase 1)Study completedNCT07266779
What this trial is testing

Bioequivalence Study of Test Product (T) of Ertugliflozin/Metformin 7.5 mg/ 1000 mg Film Coated Tablets and Reference Product (R) of Segluromet 7.5 mg/ 1000 mg Film Coated Tablets in Healthy, Adult, Human Subjects Under Fed Condition.

Who this might be right for
Type 2 Diabetes
Humanis Saglık Anonim Sirketi 36
Post-approval studies (Phase 4)Looking for participantsNCT06983054
What this trial is testing

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes

Who this might be right for
Type 2 Diabetes
Amsterdam UMC, location VUmc 34
Post-approval studies (Phase 4)Looking for participantsNCT06580717
What this trial is testing

ENavogliflozin DElivering Alleviation of Ventricular Diastolic Dysfunction in nonObstRuctive Hypertrophic CardioMyopathy

Who this might be right for
Nonobstructive Hypertrophic Cardiomyopathy
Yonsei University 200
Testing effectiveness (Phase 2)Study completedNCT01059825
What this trial is testing

Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)

Who this might be right for
Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC 375
Post-approval studies (Phase 4)Not Yet RecruitingNCT07621380
What this trial is testing

Ertugliflozin's Effect on Heart Function in Diabetic Patients After Myocardial Infarction

Who this might be right for
Type 2 Diabetes Mellitus Myocardial Infarction
Shanghai Zhongshan Hospital 476
Very early researchStudy completedNCT04167761
What this trial is testing

Ertugliflozin: Cardioprotective Effects on Epicardial Fat

Who this might be right for
Cardiovascular DiseasesAtherosclerosisType 2 Diabetes+1 more
Stanford University 61
Post-approval studies (Phase 4)Ended earlyNCT04071626
What this trial is testing

Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failure

Who this might be right for
Heart Failure, DiastolicDiabetes Mellitus, Type 2
University Hospitals Cleveland Medical Center 9
Post-approval studies (Phase 4)WithdrawnNCT03640221
What this trial is testing

Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes.

Who this might be right for
HypertensionDiabetes Mellitus, Type 2
Cedars-Sinai Medical Center
Large-scale testing (Phase 3)Study completedNCT03717194
What this trial is testing

Effect of Ertugliflozin on Cardiac Function in Diabetes

Who this might be right for
Type2 DiabetesHeart Failure
Soo Lim 102
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