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Results for “Ertugliflozin”

39 trials

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Showing 20 of 39 results

Early research (Phase 1)Study completedNCT01127308
What this trial is testing

A Radiolabeled Mass Balance Study of [14C]-Ertugliflozin (PF04971729, MK-8835) In Healthy Male Participants (MK-8835-038)

Who this might be right for
Type 2 Diabetes Mellitus (T2DM)
Merck Sharp & Dohme LLC 6
Testing effectiveness (Phase 2)Looking for participantsNCT04438213
What this trial is testing

Ertugliflozin in Chronic Heart Failure

Who this might be right for
Heart Failure
Yale University 60
Early research (Phase 1)Study completedNCT01018823
What this trial is testing

A Multiple Dose Study Of Ertugliflozin (PF-04971729, MK-8835) In Otherwise Healthy Overweight And Obese Volunteers (MK-8835-037)

Who this might be right for
Healthy Volunteer
Merck Sharp & Dohme LLC 40
Large-scale testing (Phase 3)Study completedNCT02099110
What this trial is testing

Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 1,233
Large-scale testing (Phase 3)Study completedNCT01999218
What this trial is testing

Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 1,326
Testing effectiveness (Phase 2)Study completedNCT01096667
What this trial is testing

Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)

Who this might be right for
Diabetes Mellitus, Type 2Hypertension
Merck Sharp & Dohme LLC 194
Post-approval studies (Phase 4)Study completedNCT04027530
What this trial is testing

Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study.

Who this might be right for
Type 2 Diabetes MellitusDiabetic Kidney DiseaseDiabetic Nephropathy+4 more
Amsterdam UMC, location VUmc 40
Post-approval studies (Phase 4)Study completedNCT05727579
What this trial is testing

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study

Who this might be right for
Diabetes MellitusDiabetic Kidney DiseaseHypertension
Amsterdam UMC, location VUmc 41
Large-scale testing (Phase 3)Study completedNCT03717194
What this trial is testing

Effect of Ertugliflozin on Cardiac Function in Diabetes

Who this might be right for
Type2 DiabetesHeart Failure
Soo Lim 102
Large-scale testing (Phase 3)Study completedNCT04231331
What this trial is testing

Ertugliflozin for Functional Mitral Regurgitation

Who this might be right for
Mitral Valve InsufficiencyLeft Ventricular Systolic Dysfunction
Asan Medical Center 128
Post-approval studies (Phase 4)Not Yet RecruitingNCT07621380
What this trial is testing

Ertugliflozin's Effect on Heart Function in Diabetic Patients After Myocardial Infarction

Who this might be right for
Type 2 Diabetes Mellitus Myocardial Infarction
Shanghai Zhongshan Hospital 476
Large-scale testing (Phase 3)Study completedNCT02226003
What this trial is testing

Efficacy and Safety of Ertugliflozin (MK-8835/PF-04971729) With Sitagliptin in the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Diet and Exercise (MK-8835-017)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 291
Large-scale testing (Phase 3)Study completedNCT01958671
What this trial is testing

The Efficacy and Safety of Ertugliflozin Monotherapy in the Treatment of Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control Despite Diet and Exercise (MK-8835-003, VERTIS MONO)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 461
Post-approval studies (Phase 4)Looking for participantsNCT06580717
What this trial is testing

ENavogliflozin DElivering Alleviation of Ventricular Diastolic Dysfunction in nonObstRuctive Hypertrophic CardioMyopathy

Who this might be right for
Nonobstructive Hypertrophic Cardiomyopathy
Yonsei University 200
Not applicableStudy completedNCT05556291
What this trial is testing

Combination of Ertugliflozin And Sitagliptin Efficacy, Safety & Tolerability (CEASE Diabetes) Study

Who this might be right for
EfficacySafetyTolerability
Getz Pharma 190
Post-approval studies (Phase 4)Ended earlyNCT04071626
What this trial is testing

Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failure

Who this might be right for
Heart Failure, DiastolicDiabetes Mellitus, Type 2
University Hospitals Cleveland Medical Center 9
Large-scale testing (Phase 3)Study completedNCT02036515
What this trial is testing

Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 464
Early research (Phase 1)Study completedNCT07266779
What this trial is testing

Bioequivalence Study of Test Product (T) of Ertugliflozin/Metformin 7.5 mg/ 1000 mg Film Coated Tablets and Reference Product (R) of Segluromet 7.5 mg/ 1000 mg Film Coated Tablets in Healthy, Adult, Human Subjects Under Fed Condition.

Who this might be right for
Type 2 Diabetes
Humanis Saglık Anonim Sirketi 36
Large-scale testing (Phase 3)Study completedNCT02033889
What this trial is testing

Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 621
Early research (Phase 1)Study completedNCT02115347
What this trial is testing

Pharmacokinetics, Safety, and Tolerability of Ertugliflozin (MK-8835/PF-04971729) in Participants With Hepatic Impairment and in Healthy Participants (MK-8835-014)

Who this might be right for
Type 2 Diabetes MellitusHepatic Impairment
Merck Sharp & Dohme LLC 16
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