Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Ertugliflozin”

38 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 38 results

Post-approval studies (Phase 4)Looking for participantsNCT06983054
What this trial is testing

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes

Who this might be right for
Type 2 Diabetes
Amsterdam UMC, location VUmc 34
Early research (Phase 1)Study completedNCT01054300
What this trial is testing

Effects of Once and Twice Daily Dosing Regimen of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-040)

Who this might be right for
Diabetes Mellitus, Type 2Adult
Merck Sharp & Dohme LLC 52
Testing effectiveness (Phase 2)Looking for participantsNCT04438213
What this trial is testing

Ertugliflozin in Chronic Heart Failure

Who this might be right for
Heart Failure
Yale University 60
Early research (Phase 1)Study completedNCT02115347
What this trial is testing

Pharmacokinetics, Safety, and Tolerability of Ertugliflozin (MK-8835/PF-04971729) in Participants With Hepatic Impairment and in Healthy Participants (MK-8835-014)

Who this might be right for
Type 2 Diabetes MellitusHepatic Impairment
Merck Sharp & Dohme LLC 16
Early research (Phase 1)Study completedNCT07266779
What this trial is testing

Bioequivalence Study of Test Product (T) of Ertugliflozin/Metformin 7.5 mg/ 1000 mg Film Coated Tablets and Reference Product (R) of Segluromet 7.5 mg/ 1000 mg Film Coated Tablets in Healthy, Adult, Human Subjects Under Fed Condition.

Who this might be right for
Type 2 Diabetes
Humanis Saglık Anonim Sirketi 36
Testing effectiveness (Phase 2)Study completedNCT03416270
What this trial is testing

ERtugliflozin triAl in DIabetes With Preserved or Reduced ejeCtion FrAcTion mEchanistic Evaluation in Heart Failure

Who this might be right for
Type 2 Diabetes MellitusHeart Failure
University Health Network, Toronto 34
Large-scale testing (Phase 3)Study completedNCT04029480
What this trial is testing

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 166
Large-scale testing (Phase 3)Study completedNCT04231331
What this trial is testing

Ertugliflozin for Functional Mitral Regurgitation

Who this might be right for
Mitral Valve InsufficiencyLeft Ventricular Systolic Dysfunction
Asan Medical Center 128
Early research (Phase 1)Study completedNCT00989079
What this trial is testing

A Single Escalating Dose Study Of Ertugliflozin (PF-04971729, MK-8835) Under Fed and Fasted Conditons In Healthy Volunteers (MK-8835-036)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 24
Large-scale testing (Phase 3)Study completedNCT02033889
What this trial is testing

Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 621
Post-approval studies (Phase 4)Looking for participantsNCT05644717
What this trial is testing

Effect of Erugliflozin On Liver Fat, Liver Fibrosis and Glycemic Control in Type II DM Patients With NASH/NAFLD

Who this might be right for
Liver FatLiver FibrosisGlycemic Control+3 more
Getz Pharma 164
Post-approval studies (Phase 4)Ended earlyNCT04071626
What this trial is testing

Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failure

Who this might be right for
Heart Failure, DiastolicDiabetes Mellitus, Type 2
University Hospitals Cleveland Medical Center 9
Testing effectiveness (Phase 2)Study completedNCT01096667
What this trial is testing

Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)

Who this might be right for
Diabetes Mellitus, Type 2Hypertension
Merck Sharp & Dohme LLC 194
Large-scale testing (Phase 3)Ended earlyNCT04600921
What this trial is testing

Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study

Who this might be right for
Heart Failure With Reduced Ejection FractionHeart Failure With Mid Range Ejection FractionImplantable Cardioverter-Defibrillators+1 more
Medical University of Graz 55
Early research (Phase 1)Study completedNCT01223339
What this trial is testing

Evaluation of Pharmacokinetics, Safety, And Tolerability Of Ertugliflozin (PF-04971729, MK-8835) In Japanese And Western Healthy Participants (MK-8835-041)

Who this might be right for
Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC 24
Early research (Phase 1)Study completedNCT01948986
What this trial is testing

Effect of Renal Impairment on the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Ertugliflozin in Participants With Type 2 Diabetes Mellitus (MK-8835-009)

Who this might be right for
Renal ImpairmentType 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 36
Large-scale testing (Phase 3)Study completedNCT02036515
What this trial is testing

Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 464
Testing effectiveness (Phase 2)Study completedNCT01059825
What this trial is testing

Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)

Who this might be right for
Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC 375
Large-scale testing (Phase 3)Study completedNCT02226003
What this trial is testing

Efficacy and Safety of Ertugliflozin (MK-8835/PF-04971729) With Sitagliptin in the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Diet and Exercise (MK-8835-017)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 291
Early research (Phase 1)Study completedNCT01018823
What this trial is testing

A Multiple Dose Study Of Ertugliflozin (PF-04971729, MK-8835) In Otherwise Healthy Overweight And Obese Volunteers (MK-8835-037)

Who this might be right for
Healthy Volunteer
Merck Sharp & Dohme LLC 40
Load More Results