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Results for “Ertugliflozin”

38 trials

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Showing 20 of 38 results

Large-scale testing (Phase 3)Study completedNCT02036515
What this trial is testing

Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 464
Post-approval studies (Phase 4)UnknownNCT05152940
What this trial is testing

ERTU-SODIUM: Study on the Effects of Ertugliflozin on Sodium Storage, Interstitial Volume, and Plasma Volume in HFrEF

Who this might be right for
Heart Failure With Reduced Ejection FractionCongestion
Icahn School of Medicine at Mount Sinai 28
Very early researchStudy completedNCT04167761
What this trial is testing

Ertugliflozin: Cardioprotective Effects on Epicardial Fat

Who this might be right for
Cardiovascular DiseasesAtherosclerosisType 2 Diabetes+1 more
Stanford University 61
Post-approval studies (Phase 4)Looking for participantsNCT06983054
What this trial is testing

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes

Who this might be right for
Type 2 Diabetes
Amsterdam UMC, location VUmc 34
Early research (Phase 1)Study completedNCT01018823
What this trial is testing

A Multiple Dose Study Of Ertugliflozin (PF-04971729, MK-8835) In Otherwise Healthy Overweight And Obese Volunteers (MK-8835-037)

Who this might be right for
Healthy Volunteer
Merck Sharp & Dohme LLC 40
Large-scale testing (Phase 3)Study completedNCT01986855
What this trial is testing

The Efficacy and Safety of Ertugliflozin in Participants With Type 2 Diabetes Mellitus With Stage 3 Chronic Kidney Disease Who Have Inadequate Glycemic Control on Antihyperglycemic Therapy (MK-8835-001)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 468
Testing effectiveness (Phase 2)Study completedNCT01096667
What this trial is testing

Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)

Who this might be right for
Diabetes Mellitus, Type 2Hypertension
Merck Sharp & Dohme LLC 194
Early research (Phase 1)Study completedNCT01223339
What this trial is testing

Evaluation of Pharmacokinetics, Safety, And Tolerability Of Ertugliflozin (PF-04971729, MK-8835) In Japanese And Western Healthy Participants (MK-8835-041)

Who this might be right for
Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC 24
Large-scale testing (Phase 3)Study completedNCT03717194
What this trial is testing

Effect of Ertugliflozin on Cardiac Function in Diabetes

Who this might be right for
Type2 DiabetesHeart Failure
Soo Lim 102
Large-scale testing (Phase 3)Study completedNCT04231331
What this trial is testing

Ertugliflozin for Functional Mitral Regurgitation

Who this might be right for
Mitral Valve InsufficiencyLeft Ventricular Systolic Dysfunction
Asan Medical Center 128
Large-scale testing (Phase 3)Study completedNCT02630706
What this trial is testing

Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 506
Large-scale testing (Phase 3)Study completedNCT01986881
What this trial is testing

Cardiovascular Outcomes Following Ertugliflozin Treatment in Type 2 Diabetes Mellitus Participants With Vascular Disease, The VERTIS CV Study (MK-8835-004)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 8,246
Early research (Phase 1)Study completedNCT02115347
What this trial is testing

Pharmacokinetics, Safety, and Tolerability of Ertugliflozin (MK-8835/PF-04971729) in Participants With Hepatic Impairment and in Healthy Participants (MK-8835-014)

Who this might be right for
Type 2 Diabetes MellitusHepatic Impairment
Merck Sharp & Dohme LLC 16
Post-approval studies (Phase 4)Looking for participantsNCT05644717
What this trial is testing

Effect of Erugliflozin On Liver Fat, Liver Fibrosis and Glycemic Control in Type II DM Patients With NASH/NAFLD

Who this might be right for
Liver FatLiver FibrosisGlycemic Control+3 more
Getz Pharma 164
Large-scale testing (Phase 3)Ended earlyNCT04600921
What this trial is testing

Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study

Who this might be right for
Heart Failure With Reduced Ejection FractionHeart Failure With Mid Range Ejection FractionImplantable Cardioverter-Defibrillators+1 more
Medical University of Graz 55
Early research (Phase 1)Study completedNCT01127308
What this trial is testing

A Radiolabeled Mass Balance Study of [14C]-Ertugliflozin (PF04971729, MK-8835) In Healthy Male Participants (MK-8835-038)

Who this might be right for
Type 2 Diabetes Mellitus (T2DM)
Merck Sharp & Dohme LLC 6
Large-scale testing (Phase 3)Study completedNCT04029480
What this trial is testing

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Who this might be right for
Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC 166
Not applicableStudy completedNCT05556291
What this trial is testing

Combination of Ertugliflozin And Sitagliptin Efficacy, Safety & Tolerability (CEASE Diabetes) Study

Who this might be right for
EfficacySafetyTolerability
Getz Pharma 190
Post-approval studies (Phase 4)Ended earlyNCT04071626
What this trial is testing

Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failure

Who this might be right for
Heart Failure, DiastolicDiabetes Mellitus, Type 2
University Hospitals Cleveland Medical Center 9
Post-approval studies (Phase 4)Study completedNCT05727579
What this trial is testing

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study

Who this might be right for
Diabetes MellitusDiabetic Kidney DiseaseHypertension
Amsterdam UMC, location VUmc 41
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