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Results for “Erythropoietic Protoporphyria (EPP)”

31 trials

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Showing 20 of 31 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05005975
What this trial is testing

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

Who this might be right for
EPPXLP
Tanabe Pharma America, Inc. 286
Not applicableEnded earlyNCT01550705
What this trial is testing

Effect of Isoniazid on Protoporphyrin Levels in Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic Protoporphyria (EPP)X Linked Erythropoietic Protoporphyria
University of Utah 11
Not applicableStudy completedNCT05572125
What this trial is testing

Iron Therapy in Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic ProtoporphyriaIron-deficiency
Bispebjerg Hospital 10
Large-scale testing (Phase 3)Study completedNCT00004940
What this trial is testing

Phase III Study of L-Cysteine in Patients With Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic Protoporphyria
Brigham and Women's Hospital 50
Large-scale testing (Phase 3)Study completedNCT01422915
What this trial is testing

Sorbent Therapy of the Cutaneous Porphyrias

Who this might be right for
Erythropoietic Protoporphyria
Brigham and Women's Hospital 4
Testing effectiveness (Phase 2)Study completedNCT05308472
What this trial is testing

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

Who this might be right for
Erythropoietic Protoporphyria
Disc Medicine, Inc 75
Not applicableAvailableNCT07603401
What this trial is testing

Expanded Access Program of Bitopertin For Participants With EPP or XLP

Who this might be right for
Erythropoietic Protoporphyria (EPP)X-Linked Protoporphyria (XLP)
Disc Medicine, Inc
Early research (Phase 1)WithdrawnNCT07123363
What this trial is testing

Effect of Bitopertin on the Liver and on Levels of Protoporphyrin IX in Bile, Blood, Liver, and Stool in Patients With Erythropoietic Protoporphyria/X-linked Protoporphyria and Increased Liver Stiffness and/or Liver Enzymes at Baseline

Who this might be right for
Protoporphyria
Wake Forest University Health Sciences
Large-scale testing (Phase 3)Study completedNCT01605136
What this trial is testing

Phase III Confirmatory Study in Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic Protoporphyria
Clinuvel Pharmaceuticals Limited 93
Not applicableStudy completedNCT00004831
What this trial is testing

Study of Cysteine Hydrochloride for Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic Protoporphyria
FDA Office of Orphan Products Development 20
Testing effectiveness (Phase 2)Study completedNCT03520036
What this trial is testing

Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic Protoporphyria (EPP)
Tanabe Pharma America, Inc. 102
Not applicableStudy completedNCT02979249
What this trial is testing

Oral Iron for Erythropoietic Protoporphyrias

Who this might be right for
Erythropoietic ProtoporphyriaEPPX-linked Protoporphyria+1 more
Icahn School of Medicine at Mount Sinai 16
Large-scale testing (Phase 3)Study completedNCT04578496
What this trial is testing

A Safety Extension Study in Patients With Erythropoietic Protoporphyria (EPP)

Who this might be right for
Erythropoietic Protoporphyria
Clinuvel Pharmaceuticals Limited 16
Large-scale testing (Phase 3)Study completedNCT00979745
What this trial is testing

Phase III Confirmatory Study in Erythropoietic Protoporphyria (EPP)

Who this might be right for
Erythropoietic Protoporphyria
Clinuvel Pharmaceuticals Limited 74
Testing effectiveness (Phase 2)Study completedNCT01097044
What this trial is testing

Phase II Confirmatory Study in Erythropoietic Protoporphyria (EPP)

Who this might be right for
Erythropoietic Protoporphyria
Clinuvel Pharmaceuticals Limited 77
Testing effectiveness (Phase 2)Study completedNCT06971900
What this trial is testing

GATEWAY: A Phase 2a Study of PORT-77 in Adults With Erythropoietic Protoporphyria

Who this might be right for
Erythropoietic Protoporphyria (EPP)
Portal Therapeutics, Inc. 28
Not applicableStudy completedNCT01688895
What this trial is testing

Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact

Who this might be right for
Erythropoietic ProtoporphyriaEPPX-Linked Protoporphyria+5 more
Icahn School of Medicine at Mount Sinai 150
Testing effectiveness (Phase 2)Study completedNCT05020184
What this trial is testing

Effect of Oral Cimetidine in the Protoporphyrias

Who this might be right for
Erythropoietic ProtoporphyriaX-linked Protoporphyria
Amy K. Dickey, M.D. 26
Not applicableLooking for participantsNCT07567131
What this trial is testing

Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

Who this might be right for
Erythropoietic Protoporphyria (EPP)X-Linked Porphyria (XLP)
Portal Therapeutics, Inc. 50
Large-scale testing (Phase 3)Study completedNCT04402489
What this trial is testing

Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria or X-Linked Protoporphyria

Who this might be right for
EPPXLP
Tanabe Pharma America, Inc. 184
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