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Results for “Essential Thrombocythemia, ET”

91 trials

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Showing 20 of 91 results

Not applicableStudy completedNCT00433862
What this trial is testing

Molecular Changes and Biomarkers in Chronic Myeloproliferative Disorders

Who this might be right for
Polycythemia VeraEssential ThrombocytosisIdiopathic Myelofibrosis+2 more
National Institutes of Health Clinical Center (CC) 8
Large-scale testing (Phase 3)Study completedNCT01259856
What this trial is testing

Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET)

Who this might be right for
High Risk Polycythemia VeraHigh Risk Essential Thrombocythemia
Ronald Hoffman 168
Not applicableStudy completedNCT01816256
What this trial is testing

Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms

Who this might be right for
Myeloproliferative Neoplasms (MPN)Polycythemia Vera (PV)Essential Thrombocythemia (ET)+1 more
University Health Network, Toronto 102
Testing effectiveness (Phase 2)Ended earlyNCT02730884
What this trial is testing

Single-Arm Study of the Efficacy and Safety of Oral Rigosertib in Patients With Myelofibrosis (MF) and Anemia

Who this might be right for
LeukemiaMyelofibrosisAnemia+1 more
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)UnknownNCT04485260
What this trial is testing

An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to Ruxolitinib

Who this might be right for
Myelofibrosis
Kartos Therapeutics, Inc. 36
Not applicableStudy completedNCT04177576
What this trial is testing

Evaluation of New Biomarkers of Thrombosis in Myeloproliferative Neoplasms

Who this might be right for
Myeloproliferative Neoplasm
University Hospital, Bordeaux 397
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07750574
What this trial is testing

Flonoltinib Maleate Oral Regimens in Patients With Myelofibrosis

Who this might be right for
MyelofibrosisMyelofibrosis Due to and Following Polycythemia VeraMyelofibrosis Transformation in Essential Thrombocythemia+9 more
Chengdu Zenitar Biomedical Technology Co., Ltd 105
Early research (Phase 1)Ended earlyNCT01291784
What this trial is testing

Anti-TGF-beta Therapy in Patients With Myelofibrosis

Who this might be right for
MyelofibrosisPrimary MyelofibrosisPolycythemia Vera, Post-Polycythemic Myelofibrosis Phase+1 more
John Mascarenhas 3
Testing effectiveness (Phase 2)Looking for participantsNCT07612280
What this trial is testing

Phase 1/ Phase 2 Study to Assess Safety and Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With Thrombocytosis

Who this might be right for
Essential Thrombocythemia (ET)Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)Myeloproliferative Neoplasms (MPN)
Jubilant Therapeutics Inc. 30
Testing effectiveness (Phase 2)Study completedNCT01200498
What this trial is testing

Study of SB939 in Subjects With Myelofibrosis

Who this might be right for
Myeloproliferative Disorders
M.D. Anderson Cancer Center 23
Testing effectiveness (Phase 2)Looking for participantsNCT05835466
What this trial is testing

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

Who this might be right for
Myelofibrosis (PMF)Post Essential Thrombocythemia Myelofibrosis (ET-MF)Post Polycythemia Vera Related Myelofibrosis (PV-MF)
Icahn School of Medicine at Mount Sinai 10
Large-scale testing (Phase 3)Study completedNCT03952039
What this trial is testing

An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib

Who this might be right for
Primary MyelofibrosisPost-Polycythemia VeraMyelofibrosis
Celgene 202
Large-scale testing (Phase 3)Study completedNCT04173494
What this trial is testing

Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)

Who this might be right for
Primary MyelofibrosisPost-polycythemia Vera MyelofibrosisPost-essential Thrombocythemia Myelofibrosis
Sierra Oncology LLC - a GSK company 195
Large-scale testing (Phase 3)Study completedNCT01467661
What this trial is testing

Long-term Safety of SPD422 in Japanese Adults With Essential Thrombocythaemia

Who this might be right for
Essential Thrombocythemia (ET)
Shire 41
Early research (Phase 1)Looking for participantsNCT05025488
What this trial is testing

Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm

Who this might be right for
MyelofibrosisEssential ThrombocythemiaMPN
Marina Kremyanskaya 10
Large-scale testing (Phase 3)Active Not RecruitingNCT06079879
What this trial is testing

Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

Who this might be right for
Essential Thrombocythemia
Merck Sharp & Dohme LLC 340
Testing effectiveness (Phase 2)WithdrawnNCT04054245
What this trial is testing

PAT-1251 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis

Who this might be right for
Myelofibrosis Transformation in Essential ThrombocythemiaPolycythemia Vera, Post-Polycythemic Myelofibrosis PhasePrimary Myelofibrosis
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Looking for participantsNCT06552429
What this trial is testing

Peginterferon α-2b Injection for Hydroxyurea Resistant or Intolerant ET

Who this might be right for
Essential Thrombocythemia
Xiamen Amoytop Biotech Co., Ltd. 27
Early research (Phase 1)Ended earlyNCT04637009
What this trial is testing

TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMyeloproliferative NeoplasmMyelodysplastic/Myeloproliferative Neoplasm
Astex Pharmaceuticals, Inc. 20
Not applicableStudy completedNCT00715247
What this trial is testing

Polycythemia Vera, Myelofibrosis and Essential Thrombocythemia: Identification of PV, MF & ET Genes

Who this might be right for
Polycythemia VeraEssential ThrombocythemiaMyelofibrosis
University of Utah 726
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