Early research (Phase 1)Study completedNCT01971515What this trial is testingFirst-in-Human Dose Escalation Trial in Subjects With Advanced MalignanciesWho this might be right forSolid Tumor EMD Serono 101
Testing effectiveness (Phase 2)Study completedNCT00338728What this trial is testingLetrozole and Imatinib Mesylate in Treating Postmenopausal Participants With Estrogen or Progesterone Positive Metastatic Breast CancerWho this might be right forAnatomic Stage IV Breast Cancer AJCC v8Estrogen Receptor PositiveKIT Positive+4 more M.D. Anderson Cancer Center 59
Large-scale testing (Phase 3)Looking for participantsNCT07391774What this trial is testingTesting Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low TrialWho this might be right forAnatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIC Breast Cancer AJCC v8+2 more National Cancer Institute (NCI)
Large-scale testing (Phase 3)Looking for participantsNCT06382948What this trial is testingElacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.Who this might be right forAdvanced Breast CancerER-positive Breast CancerHER2-negative Breast Cancer+1 more MedSIR 300
Post-approval studies (Phase 4)Looking for participantsNCT05333328What this trial is testingOFS in Premenopausal Node+ Breast Cancer With Low Genomic RiskWho this might be right forBreast CancerEstrogen Receptor Positive TumorHER2-negative Breast Cancer+2 more Gangnam Severance Hospital 418
Not applicableStudy completedNCT06344767What this trial is testingPositive ER Expression Assessed by 18F-FES PET/CT in the MBC with ER-negative Primary TumorWho this might be right forBreast Cancer Fudan University 19
Very early researchStudy completedNCT03122444What this trial is testingImipramine on ER+ve and Triple Negative Breast CancerWho this might be right forBreast Cancer The University of Texas Health Science Center at San Antonio 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07786051What this trial is testingDiEtary Mimicry by Glucocorticoid Modulation Evaluation in ER+ Metastatic Breast Cancer Treatment: Efficacy and Response (DEMETER Trial)Who this might be right forBreast Cancer The Netherlands Cancer Institute 80
Testing effectiveness (Phase 2)Looking for participantsNCT06176261What this trial is testingDATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEsWho this might be right forBreast CancerBreast Cancer FemaleMetastatic Triple-Negative Breast Carcinoma+4 more Nancy Lin, MD 58
Not applicableStudy completedNCT03715959What this trial is testingNipple Aspirate Fluid in Detecting Breast CancerWho this might be right forAnatomic Stage IA Breast Cancer AJCC v8Anatomic Stage IB Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8+25 more Ohio State University Comprehensive Cancer Center 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT02712723What this trial is testingLetrozole Plus Ribociclib or Placebo as Neo-adjuvant Therapy in ER-positive, HER2-negative Early Breast CancerWho this might be right forBreast Cancer Qamar Khan 121
Testing effectiveness (Phase 2)Looking for participantsNCT04585750What this trial is testingThe Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)Who this might be right forAdvanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more PMV Pharmaceuticals, Inc 300
Testing effectiveness (Phase 2)Looking for participantsNCT07014410What this trial is testingPyrotinib Combined With Dalpiciclib Combined With Letrozole in ER-positive and HER2-positive Advanced Breast CancerWho this might be right forBreast Cancer Zhejiang Cancer Hospital 63
Testing effectiveness (Phase 2)UnknownNCT02910050What this trial is testingBicalutamide Plus Aromatase Inhibitors in ER(+)/AR(+)/HER2(-) Metastatic Breast CancerWho this might be right forBreast Cancer Xu fei 58
Large-scale testing (Phase 3)Not Yet RecruitingNCT06407401What this trial is testingImprovement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Patients With Early Breast CancerWho this might be right forER+ Breast CancerHER2-negative Breast CancerBreast Cancer Stage I+4 more European Organisation for Research and Treatment of Cancer - EORTC 399
Testing effectiveness (Phase 2)Active Not RecruitingNCT02955394What this trial is testingPreoperative Fulvestrant With or Without Enzalutamide in ER+/Her2- Breast CancerWho this might be right forBreast Cancer University of Colorado, Denver 61
Testing effectiveness (Phase 2)Ended earlyNCT03872388What this trial is testingAtorvastatin in Treating Patients With Stage IIb-III Triple Negative Breast Cancer Who Did Not Achieve a Pathologic Complete Response After Receiving Neoadjuvant ChemotherapyWho this might be right forAnatomic Stage IIB Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8+17 more M.D. Anderson Cancer Center 6
Not applicableStudy completedNCT00755313What this trial is testingEffects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast CancerWho this might be right forBreast CancerChemotherapeutic Agent ToxicityCognitive/Functional Effects+4 more University of California, San Francisco 81
Testing effectiveness (Phase 2)Study completedNCT02811497What this trial is testingStudy of Azacitidine and Durvalumab in Advanced Solid TumorsWho this might be right forMicrosatellite Stable Colorectal CarcinomaPlatinum Resistant Epithelial Ovarian Cancer Type IIEstrogen Receptor Positive and HER2 Negative Breast Cancer University Health Network, Toronto 28
Early research (Phase 1)Study completedNCT04514159What this trial is testingZN-c5 and Abemaciclib in Participants With Breast CancerWho this might be right forBreast Cancer Zeno Alpha Inc. 14