Testing effectiveness (Phase 2)UnknownNCT04296851What this trial is testingNiclosamide for Familial Adenomatous PolyposisWho this might be right forFamilial Adenomatous Polyposis Yonsei University 72
Early research (Phase 1)Study completedNCT05201911What this trial is testingCharacterize the Biodistribution of 124I-Labeled AT-03 in Patients With Systemic AmyloidosisWho this might be right forAmyloidosis; Systemic Attralus, Inc. 13
Large-scale testing (Phase 3)Study completedNCT00925002What this trial is testingSafety And Efficacy Evaluation Of Fx-1006A In Subjects With Transthyretin AmyloidosisWho this might be right forATTR-PN Pfizer 93
Not applicableLooking for participantsNCT07205666What this trial is testingThe Eplontersen Pregnancy and Lactation Outcomes StudyWho this might be right forTransthyretin Amyloidosis AstraZeneca 10
Very early researchLooking for participantsNCT07808177What this trial is testingClinical Evaluation of 177Lu-FAP-VG11 Injection in Patients With Fibroblast Activation Protein -Positive Advanced Solid TumoursWho this might be right forFibroblast Activation Protein (FAP)-Positive Advanced Solid Tumours Shandong Cancer Hospital and Institute 7
Early research (Phase 1)Not Yet RecruitingNCT07363369What this trial is testingExploratory Clinical Study of FAP mRNA Vaccine in Patients With Advanced Malignant Solid TumorsWho this might be right forAdvanced Malignant Solid Tumors West China Hospital 10
Not applicableLooking for participantsNCT07112066What this trial is testingMultimodality Cardiac Imaging for Disease Progression in ATTR-CMWho this might be right forAmyloidosis Cardiac Dominik Benz 50
Very early researchStudy completedNCT04899180What this trial is testingPrevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic StenosisWho this might be right forAortic StenosisTransthyretin AmyloidosisTransthyretin Amyloid Cardiomyopathy+1 more Mayo Clinic 4
Not applicableLooking for participantsNCT06557590What this trial is testing18F-FAPI-04 PET/CT and PET/MR in Patients With Various Types of Malignant TumorsWho this might be right forCancerFAP Hunan Cancer Hospital 500
Early research (Phase 1)Study completedNCT02627274What this trial is testingA Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)Who this might be right forSolid TumorBreast CancerCancer of Head and Neck Hoffmann-La Roche 134
Not applicableStudy completedNCT06365593What this trial is testingHATTR Polyneuropathy in RussiaWho this might be right forHereditary Transthyretin Amyloidosis AstraZeneca 100
Large-scale testing (Phase 3)Ended earlyNCT00585312What this trial is testingTrial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)Who this might be right forAdenomatous Polyposis Coli Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 106
Early research (Phase 1)UnknownNCT03932565What this trial is testingInterventional Therapy Sequential With the Fourth-generation CAR-T Targeting Nectin4/FAP for Malignant Solid TumorsWho this might be right forNectin4-positive Advanced Malignant Solid Tumor The Sixth Affiliated Hospital of Wenzhou Medical University 30
Testing effectiveness (Phase 2)Study completedNCT01725490What this trial is testingThe Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled StudyWho this might be right forFamilial Adenomatous Polyposis Yonsei University 34
Not applicableStudy completedNCT03720275What this trial is testingEarly and Systematic Screening in Chronic NeuropathyWho this might be right forAmyloid Neuropathies, Familial University Hospital, Bordeaux 130
Testing effectiveness (Phase 2)Looking for participantsNCT06189820What this trial is testingRole of the Fibroblast Activation Protein (FAP) as Biomarker of Fibrotic Lung DiseasesWho this might be right forPulmonary FibrosisLung FibrosisIdiopathic Pulmonary Fibrosis+1 more Erasme University Hospital 70
Testing effectiveness (Phase 2)Study completedNCT00630864What this trial is testingThe Effects of Fx-1006A on Transthyretin Stabilization and Clinical Outcome Measures in Patients With Non-V30M Transthyretin AmyloidosisWho this might be right forTransthyretin-associated Amyloidosis With Polyneuropathy Pfizer 21
Large-scale testing (Phase 3)Study completedNCT03333265What this trial is testingPrimary Chemoprevention of Familial Adenomatous Polyposis With Berberine HydrochlorideWho this might be right forColorectal Adenomas Xijing Hospital of Digestive Diseases 100
Very early researchLooking for participantsNCT07689643What this trial is testingSafety and Preliminary Efficacy of [177Lu]Lu-RTX-2358 Combined With Immune Checkpoint Inhibitors in Patients With FAP-positive Metastatic Non-Small Cell Lung CancerWho this might be right forMetastatic Non-small Cell Lung Cancer Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 36
Not applicableStudy completedNCT03431896What this trial is testingMonitoring of Early Disease Progression in Hereditary Transthyretin AmyloidosisWho this might be right forAmyloidosisAmyloidAmyloid Neuropathies, Familial+4 more The Cleveland Clinic 37