Not applicableLooking for participantsNCT07142226What this trial is testingRole of ctDNA in Genetic Profiling & Outcomes for Advanced BTCWho this might be right forBiliary Tract Cancer CHA University 200
Testing effectiveness (Phase 2)Study completedNCT01752920What this trial is testingPhase 1/2 Study of Derazantinib (ARQ 087) in Adult Subjects With Advanced Solid Tumors With FGFR Genetic AlterationsWho this might be right forSolid Tumor Basilea Pharmaceutica 119
Large-scale testing (Phase 3)Not Yet RecruitingNCT07328919What this trial is testingEfficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or MutationsWho this might be right forIntrahepatic Cholangiocarcinoma (Icc)Advanced Cholangiocarcinoma TransThera Sciences (Nanjing), Inc. 138
Large-scale testing (Phase 3)Ended earlyNCT03773302What this trial is testingPhase 3 Study of BGJ398 (Oral Infigratinib) in First Line Cholangiocarcinoma With FGFR2 Gene Fusions/TranslocationsWho this might be right forAdvanced CholangiocarcinomaFGFR2 Gene Mutation QED Therapeutics, a BridgeBio company 48
Not applicableLooking for participantsNCT07151118What this trial is testingCtDNA in Genetic Profiling and Clinical Outcomes of Advanced Biliary Tract CancerWho this might be right forBiliary Tract Cancer CHA University 100
Testing effectiveness (Phase 2)Study completedNCT03230318What this trial is testingDerazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic CholangiocarcinomaWho this might be right forIntrahepatic CholangiocarcinomaCombined Hepatocellular and Cholangiocarcinoma Basilea Pharmaceutica 148
Large-scale testing (Phase 3)Ended earlyNCT04093362What this trial is testingFutibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene RearrangementsWho this might be right forAdvanced CholangiocarcinomaFGFR2 Gene Rearrangements Taiho Oncology, Inc. 10
Testing effectiveness (Phase 2)Study completedNCT04919642What this trial is testingStudy to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in CholangiocarcinomaWho this might be right forCholangiocarcinomaFGFR2 FusionFGFR2 Gene Mutation+2 more TransThera Sciences (Nanjing), Inc. 55
Testing effectiveness (Phase 2)Looking for participantsNCT06906562What this trial is testingA Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic AlterationsWho this might be right forAdvanced Pancreatic CarcinomaMetastatic Pancreatic CarcinomaStage II Pancreatic Cancer AJCC v8+2 more Sameek Roychowdhury 40
Early research (Phase 1)WithdrawnNCT05510427What this trial is testingPhase Ib Trial of Infigratinib In Combination With Atezolizumab And Bevacizumab for The Second-Line Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion/AmplificationWho this might be right forCholangiocarcinomaLiver Cancer M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Looking for participantsNCT07359820What this trial is testingLirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or RearrangementWho this might be right forFGFR2 Gene Fusion/RearrangementOther Solid Tumors, Adult Elevar Therapeutics 30
Testing effectiveness (Phase 2)Ended earlyNCT05565794What this trial is testingPemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/RearrangementsWho this might be right forIntrahepatic CholangiocarcinomaFGFR2 Gene MutationFGFR2 Gene Rearrangement+1 more Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 2
Testing effectiveness (Phase 2)WithdrawnNCT05222165What this trial is testingStudy With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 AlterationsWho this might be right forAdvanced Solid TumorCNS TumorRecurrent WHO Grade II Glioma Helsinn Healthcare SA
Not applicableUnknownNCT04921553What this trial is testingReal Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING)Who this might be right forCancerCancer MetastaticNTRK Gene Fusion Overexpression+13 more Centre Leon Berard 500
Not applicableLooking for participantsNCT06793709What this trial is testingA Post-marketing Observational Study of Tasfygo in Participants With Unresectable Biliary Tract Cancer With Fibroblast Growth Factor Receptor 2 (FGFR2) Fusion Gene Positivity Who Progressed After ChemotherapyWho this might be right forBiliary Tract Cancer Eisai Co., Ltd. 60
Early research (Phase 1)Study completedNCT01004224What this trial is testingA Dose Escalation Study in Adult Patients With Advanced Solid MalignanciesWho this might be right forAdvanced Solid Tumors With Alterations of FGFR1, 2 and or 3Squamous Lung Cancer With FGFR1 AmplificationBladder Cancer With FGFR3 Mutation or Fusion+3 more Novartis Pharmaceuticals 208
Early research (Phase 1)Active Not RecruitingNCT06160752What this trial is testingSafety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene AlterationsWho this might be right forLocally Advanced CholangiocarcinomaIntrahepatic CholangiocarcinomaSolid Tumor+1 more Tyra Biosciences, Inc 40
Testing effectiveness (Phase 2)Looking for participantsNCT05727176What this trial is testingStudy of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or RearrangementWho this might be right forAdvanced CholangiocarcinomaFGFR2 FusionsGene Rearrangement Taiho Oncology, Inc. 120
Testing effectiveness (Phase 2)Ended earlyNCT02150967What this trial is testingA Phase II, Single Arm Study of BGJ398 in Patients With Advanced CholangiocarcinomaWho this might be right forAdvanced CholangiocarcinomaFGFR2 Gene Mutation QED Therapeutics, a BridgeBio company 143
Testing effectiveness (Phase 2)Ended earlyNCT03834220What this trial is testingBasket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)Who this might be right forSolid Tumor Debiopharm International SA 63