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Results for “FLAG Chemotherapy”

13 trials

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Showing 13 of 13 results

Testing effectiveness (Phase 2)Looking for participantsNCT07046078
What this trial is testing

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaChronic Myelomonocytic Leukemia+1 more
Fred Hutchinson Cancer Center 20
Testing effectiveness (Phase 2)UnknownNCT04112589
What this trial is testing

A Clinical Trial to Assess the Efficacy and Safety of the Combination of a Drug Call Quizartinib With Chemotherapy (FLAG-IDA) in Patients With Acute Myeloid Leukemia That Has Not Responded to the First Treatment or That Has Returned After the First Treatment

Who this might be right for
Acute Myeloid Leukemia
PETHEMA Foundation 63
Early research (Phase 1)Active Not RecruitingNCT06034470
What this trial is testing

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaMyelodysplastic Syndrome+2 more
Fred Hutchinson Cancer Center 30
Early research (Phase 1)WithdrawnNCT02791919
What this trial is testing

Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
CNS 2aCNS 2bCNS 2c+3 more
National Cancer Institute (NCI)
Early research (Phase 1)Ended earlyNCT04250051
What this trial is testing

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic SyndromeRecurrent Myeloproliferative Neoplasm+5 more
Northwestern University 2
Early research (Phase 1)Ended earlyNCT01701323
What this trial is testing

Expanded Cord Blood Cell Infusion Following Combination Chemotherapy in Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid Leukemia
Nohla Therapeutics, Inc. 7
Early research (Phase 1)WithdrawnNCT07428486
What this trial is testing

FLAG Chemotherapy In Combination With Lisaftoclax And Pelcitoclax In Patients With Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia

Who this might be right for
Phase IFLAG ChemotherapyLisaftoclax+3 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT05780879
What this trial is testing

A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia

Who this might be right for
Secondary Acute Myeloid Leukemia
University of Michigan Rogel Cancer Center 10
Testing effectiveness (Phase 2)Looking for participantsNCT06928662
What this trial is testing

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse

Who this might be right for
Acute Myeloid LeukemiaAcute Undifferentiated LeukemiaMixed Phenotype Acute Leukemia+11 more
Fred Hutchinson Cancer Center 36
Testing effectiveness (Phase 2)Study completedNCT00003619
What this trial is testing

Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaMyelodysplastic Syndromes+1 more
Drexel University College of Medicine
Early research (Phase 1)Looking for participantsNCT04375631
What this trial is testing

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+6 more
Fred Hutchinson Cancer Center 120
Post-approval studies (Phase 4)Study completedNCT00487448
What this trial is testing

SMD_FLAG-IDA_98: FLAG-IDA in Induction Treatment of High Risk Myelodysplastic Syndromes or Secondary Acute Myeloblastic Leukemia

Who this might be right for
Myelodysplastic SyndromeAcute Myeloblastic Leukemia
PETHEMA Foundation 200
Testing effectiveness (Phase 2)Looking for participantsNCT03214562
What this trial is testing

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
High Risk Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
M.D. Anderson Cancer Center 116