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Results for “FLT3 Internal Tandem Duplication Positive”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Ended earlyNCT04209725
What this trial is testing

CPX-351 (Vyxeos™) With Quizartinib for the Treatment of FLT3-ITD Mutation-Positive Acute Myeloid Leukemia

Who this might be right for
Leukemia, Myeloid, Acute
SCRI Development Innovations, LLC 1
Testing effectiveness (Phase 2)Study completedNCT02984995
What this trial is testing

Phase 2 Study of Quizartinib in Participants With Acute Myeloid Leukemia (AML) FLT3 Internal Tandem Duplication (FLT3/ITD) Mutation

Who this might be right for
Leukemia, Myeloid, Acute
Daiichi Sankyo Co., Ltd. 37
Testing effectiveness (Phase 2)Study completedNCT01349049
What this trial is testing

Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Daiichi Sankyo 90
Large-scale testing (Phase 3)Study completedNCT02668653
What this trial is testing

Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid LeukemiaLeukemia
Daiichi Sankyo 539
Testing effectiveness (Phase 2)Looking for participantsNCT07259707
What this trial is testing

Gilteritinib Plus VA Followed By Consolidation Chemotherapy in Newly Diagnosed FLT3-ITD+ AML

Who this might be right for
Acute Myeloid LeukemiaFLT3 Internal Tandem Duplication PositiveIntermediate Risk Acute Myeloid Leukemia+1 more
First Affiliated Hospital of Zhejiang University 25
Early research (Phase 1)Looking for participantsNCT07162116
What this trial is testing

Evaluate the Effect of XY0206 on the QTc Interval in Chinese Healthy Participants

Who this might be right for
Acute Myeloid Leukemia With FLT3/ITD Mutation
Shijiazhuang Yiling Pharmaceutical Co. Ltd 45
Testing effectiveness (Phase 2)Ended earlyNCT01846624
What this trial is testing

Decitabine and Midostaurin in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia (AML) With Multilineage Dysplasia Following Myelodysplastic Syndrome, in AdultsAML (Adult) With 11q23 (MLL) AbnormalitiesAML (Adult) With Del (5q)+5 more
David Iberri 13
Early research (Phase 1)Ended earlyNCT03552029
What this trial is testing

Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Daiichi Sankyo 10
Testing effectiveness (Phase 2)Ended earlyNCT03333486
What this trial is testing

Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Leukemia in RemissionAcute Lymphoblastic Leukemia+34 more
Roswell Park Cancer Institute 31
Not applicableUnknownNCT05596968
What this trial is testing

The Gut Microbiome and Sorafenib Maintenance Therapy in FLT3-ITD Positive AML After Allo-HSCT

Who this might be right for
Acute Myeloid Leukemia With FLT3/ITD MutationAllogeneic Hematopoietic Stem Cell Transplantation
Nanfang Hospital, Southern Medical University 37
Large-scale testing (Phase 3)Looking for participantsNCT07463651
What this trial is testing

MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib

Who this might be right for
Acute Myeloid Leukemia (AML)FLT3-ITD MutationAllogeneic Hematopoietic Cell Transplantation (HCT)+3 more
The First Affiliated Hospital of Soochow University 594
Testing effectiveness (Phase 2)Active Not RecruitingNCT03793478
What this trial is testing

Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood

Who this might be right for
Acute Myeloid Leukemia
Daiichi Sankyo 65
Not applicableStudy completedNCT04788420
What this trial is testing

Influence of Co-existing Mutations on Sorafenib Maintenance Therapy After Allo-HSCT for Patients With FLT3-ITD AML

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia With FLT3/ITD MutationHematopoietic Stem Cell Transplantation
Nanfang Hospital, Southern Medical University 456
Large-scale testing (Phase 3)Study completedNCT02039726
What this trial is testing

(QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Who Are FLT3-ITD Positive

Who this might be right for
AML
Daiichi Sankyo 367
Testing effectiveness (Phase 2)Study completedNCT01760655
What this trial is testing

Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia With FLT3/ITD MutationAcute Myeloid Leukemia With Gene MutationsAcute Myeloid Leukemia With Inv(3) (q21.3;q26.2); GATA2, MECOM+18 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 62
Testing effectiveness (Phase 2)Study completedNCT01565668
What this trial is testing

Open Label Study to Evaluate Safety and Efficacy of 2 Doses of Quizartinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Leukemia, Myeloid, Acute
Daiichi Sankyo 76
Testing effectiveness (Phase 2)Study completedNCT01892371
What this trial is testing

Quizartinib With Azacitidine or Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
FLT3 Gene Mutation NegativeFLT3 Internal Tandem Duplication PositiveRecurrent Acute Myeloid Leukemia+5 more
M.D. Anderson Cancer Center 73
Testing effectiveness (Phase 2)Ended earlyNCT04240002
What this trial is testing

Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia With FMS-like Tyrosine Kinase 3 (FLT3) Mutation / Internal Tandem Duplication (ITD)
Astellas Pharma Global Development, Inc. 9
Testing effectiveness (Phase 2)Study completedNCT01534260
What this trial is testing

Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib for the Treatment of Acute Myeloid Leukemia With Complex- or Poor-risk (Monosomy 5/7) Cytogenetics or FLT3-ITD Positive Genotype

Who this might be right for
Acute Myeloid Leukemia
Hamid Sayar 37
Not applicableUnknownNCT05596981
What this trial is testing

The Gut Microbiome in FLT3-ITD+ AML Undergoing Allo-HSCT With Or Without Sorafenib Maintenance After Allo-HSCT

Who this might be right for
Acute Myeloid Leukemia With FLT3/ITD MutationAllogeneic Hematopoietic Stem Cell Transplantation
Nanfang Hospital, Southern Medical University 60
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