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Results for “FLT3-ITD”

71 trials

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Showing 20 of 71 results

Testing effectiveness (Phase 2)Ended earlyNCT02634827
What this trial is testing

Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation

Who this might be right for
Acute Myeloid Leukemia With FLT3/ITD MutationAcute Myeloid Leukemia With Gene MutationsFLT3 Tyrosine Kinase Domain Point Mutation+2 more
Mayo Clinic 1
Not applicableStudy completedNCT05193448
What this trial is testing

A Non-interventional Ambispective Real-world Cohort of rEfractory and reLapsed (R/R) FLT3 Mutated Acute MyEloid Leukemia (AML) Patients Treated With Gilteritinib in FrANCE

Who this might be right for
Refractory AMLRelapsed Adult AMLFLT3-TKD Mutation+1 more
French Innovative Leukemia Organisation 177
Large-scale testing (Phase 3)Study completedNCT02668653
What this trial is testing

Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid LeukemiaLeukemia
Daiichi Sankyo 539
Testing effectiveness (Phase 2)Study completedNCT01892371
What this trial is testing

Quizartinib With Azacitidine or Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
FLT3 Gene Mutation NegativeFLT3 Internal Tandem Duplication PositiveRecurrent Acute Myeloid Leukemia+5 more
M.D. Anderson Cancer Center 73
Early research (Phase 1)Active Not RecruitingNCT05918692
What this trial is testing

BMF-500 in Adults With Acute Leukemia

Who this might be right for
Acute Myeloid Leukemia
Biomea Fusion Inc. 35
Testing effectiveness (Phase 2)Looking for participantsNCT06824168
What this trial is testing

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

Who this might be right for
Acute Myeloid LeukemiaLeukemia
Daiichi Sankyo 130
Testing effectiveness (Phase 2)Study completedNCT03622541
What this trial is testing

Using Sorafenib as a Salvage Treatment for Relapsed or Refractory Acute Myeloid Leukemia Carrying FLT3-ITD

Who this might be right for
FLT3-ITD MutationAML
The University of Hong Kong 46
Testing effectiveness (Phase 2)Ended earlyNCT01846624
What this trial is testing

Decitabine and Midostaurin in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia (AML) With Multilineage Dysplasia Following Myelodysplastic Syndrome, in AdultsAML (Adult) With 11q23 (MLL) AbnormalitiesAML (Adult) With Del (5q)+5 more
David Iberri 13
Early research (Phase 1)Ended earlyNCT03552029
What this trial is testing

Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Daiichi Sankyo 10
Large-scale testing (Phase 3)Not Yet RecruitingNCT05876832
What this trial is testing

XY0206 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory AML With FLT3-ITD-Mutation (ALIVE)

Who this might be right for
Acute Myeloid Leukemia With FLT3/ITD Mutation
Shijiazhuang Yiling Pharmaceutical Co. Ltd 312
Not applicableNo Longer AvailableNCT03746912
What this trial is testing

Expanded Treatment Protocol for Adults With FLT3-ITD Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) to Receive Quizartinib

Who this might be right for
Acute Myeloid Leukemia With Gene Mutations
Daiichi Sankyo
Testing effectiveness (Phase 2)Ended earlyNCT01028716
What this trial is testing

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more
Fred Hutchinson Cancer Center 46
Testing effectiveness (Phase 2)Study completedNCT02530476
What this trial is testing

Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

Who this might be right for
LeukemiaAcute Myeloid Leukemia
M.D. Anderson Cancer Center 17
Testing effectiveness (Phase 2)Looking for participantsNCT04278768
What this trial is testing

Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
Curis, Inc. 366
Large-scale testing (Phase 3)UnknownNCT03642236
What this trial is testing

Combination of BTK Inhibitor Overcomes Drug-resistance in Refractory/Relapsed FLT3 Mutant AML

Who this might be right for
FLT3-ITD MutationAcute Myeloid LeukemiaBrutons Tyrosine Kinase
Nanfang Hospital, Southern Medical University 122
Testing effectiveness (Phase 2)Study completedNCT02927262
What this trial is testing

ASP2215 (Gilteritinib), Administered as Maintenance Therapy Following Induction/Consolidation Therapy for Subjects With FMS-like Tyrosine Kinase 3 (FLT3/ITD) Acute Myeloid Leukemia (AML) in First Complete Remission

Who this might be right for
Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) / Internal Tandem Duplication (ITD) Mutation
Astellas Pharma Global Development, Inc. 98
Testing effectiveness (Phase 2)Study completedNCT01883362
What this trial is testing

Standard of Care +/- Midostaurin to Prevent Relapse Post Stem Cell Transplant in Patients With FLT3-ITD Mutated AML

Who this might be right for
Acute Myeloid Leukemia
Novartis Pharmaceuticals 60
Testing effectiveness (Phase 2)UnknownNCT03135054
What this trial is testing

Combination of Quizartinib and Omacetaxine Mepesuccinate for AML Carrying FLT3-ITD

Who this might be right for
AMLFLT3-ITD Mutation
The University of Hong Kong 40
Not applicableUnknownNCT05383014
What this trial is testing

FLT3-ITD Gene Mutation and CD135 Expression in Acute Myeloid Leukemia.

Who this might be right for
Acute Myeloid Leukemia
Assiut University 82
Not applicableStudy completedNCT04788420
What this trial is testing

Influence of Co-existing Mutations on Sorafenib Maintenance Therapy After Allo-HSCT for Patients With FLT3-ITD AML

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia With FLT3/ITD MutationHematopoietic Stem Cell Transplantation
Nanfang Hospital, Southern Medical University 456
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