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Results for “Factor VIII (FVIII) Gene”

41 trials

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Showing 20 of 41 results

Not applicableWithdrawnNCT06634836
What this trial is testing

Patient Interview Study to Explore the Impact of Gene Therapy in Hemophilia A & B

Who this might be right for
Hemophilia AHemophilia B
Pfizer
Not applicableLooking for participantsNCT04728841
What this trial is testing

Gene Therapy for Chinese Hemophilia A

Who this might be right for
Hemophilia AGene Therapy
Institute of Hematology & Blood Diseases Hospital, China 12
Testing effectiveness (Phase 2)Study completedNCT03734588
What this trial is testing

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

Who this might be right for
Adeno-Associated Virus (AAV)Blood Coagulation DisorderBlood Coagulation Disorders, Inherited+14 more
Spark Therapeutics, Inc. 4
Early research (Phase 1)Study completedNCT05265767
What this trial is testing

Hematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A

Who this might be right for
Hemophilia A
Christian Medical College, Vellore, India 6
Not applicableLooking for participantsNCT06147414
What this trial is testing

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

Who this might be right for
Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, IncludingSickle Cell DiseaseCystic Fibrosis+12 more
Assistance Publique - Hôpitaux de Paris 550
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07226206
What this trial is testing

A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

Who this might be right for
Hemophilia A
Hoffmann-La Roche 5
Not applicableNot Yet RecruitingNCT04883710
What this trial is testing

The World Federation of Hemophilia Gene Therapy Registry

Who this might be right for
Hemophilia
World Federation of Hemophilia 5,000
Very early researchLooking for participantsNCT05152732
What this trial is testing

Safety and Tolerability of VGB-R04 in Patients With Haemophilia B

Who this might be right for
Hemophilia B
Institute of Hematology & Blood Diseases Hospital, China 3
Large-scale testing (Phase 3)Study completedNCT03569891
What this trial is testing

HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients

Who this might be right for
Hemophilia B
CSL Behring 67
Early research (Phase 1)Not Yet RecruitingNCT04418414
What this trial is testing

Hematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A

Who this might be right for
Hemophilia A
Expression Therapeutics, LLC 7
Testing effectiveness (Phase 2)Study completedNCT02576795
What this trial is testing

Gene Therapy Study in Severe Haemophilia A Patients (270-201)

Who this might be right for
Severe Haemophilia A
BioMarin Pharmaceutical 15
Not applicableEnrolling By InvitationNCT05768386
What this trial is testing

A Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical Trial (270-401)

Who this might be right for
Hemophilia A
BioMarin Pharmaceutical 172
Early research (Phase 1)Active Not RecruitingNCT03818763
What this trial is testing

Gene Therapy Trial for Platelet Derived Factor VIII Production in Hemophilia A

Who this might be right for
Hemophilia A
Medical College of Wisconsin 5
Large-scale testing (Phase 3)Active Not RecruitingNCT06224907
What this trial is testing

Phase 3 Study for Efficacy and Safety Outcomes Data in Japanese Patients With Severe Hemophilia A

Who this might be right for
Hemophilia A
BioMarin Pharmaceutical 6
Testing effectiveness (Phase 2)Study completedNCT03003533
What this trial is testing

A Gene Transfer Study for Hemophilia A

Who this might be right for
Hemophilia A
Spark Therapeutics, Inc. 25
Large-scale testing (Phase 3)Study completedNCT03392974
What this trial is testing

Single-Arm Study To Evaluate The Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia A Patients at a Dose of 4E13 vg/kg

Who this might be right for
Hemophilia A
BioMarin Pharmaceutical 1
Testing effectiveness (Phase 2)Ended earlyNCT03520712
What this trial is testing

Gene Therapy Study in Severe Hemophilia A Patients With Antibodies Against AAV5

Who this might be right for
Hemophilia AGene TherapyClotting Disorders+1 more
BioMarin Pharmaceutical 3
Large-scale testing (Phase 3)WithdrawnNCT06297486
What this trial is testing

Study of a Gene Therapy Treatment for Hemophilia A

Who this might be right for
Hemophilia A
Spark Therapeutics, Inc.
Not applicableLooking for participantsNCT04817462
What this trial is testing

Liver Biopsy In Haemophilia Gene Therapy

Who this might be right for
Hemophilia B, SevereHemophilia A, Severe
University College, London 10
Not applicableNot Yet RecruitingNCT05932914
What this trial is testing

Liver Biopsy Following Gene Therapy For Hemophilia

Who this might be right for
Hemophilia AHemophilia B
St. Jude Children's Research Hospital 8
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