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Results for “Failed Tyrosine Kinase Inhibitors”

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Showing 6 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07158840
What this trial is testing

AK112 in Non-squamous Non-small Cell Lung Cancer (NSCLC)Patients With Actionable Genomic Alterations (AGA) Who Have Failed to Previous Tyrosine Kinase Inhibitor (TKI) Treatment

Who this might be right for
Non-Small Cell Lung Cancer
Akeso 60
Large-scale testing (Phase 3)UnknownNCT05311943
What this trial is testing

Treatment With Olverembatinib in CML-CP Patients Who Failed to at Least Two Previously Administered Second-generation TKIs.

Who this might be right for
OlverembatinibChronic Myeloid Leukemia, Chronic PhaseTyrosine Kinase Inhibitors
Shenzhen Second People's Hospital 40
Large-scale testing (Phase 3)Active Not RecruitingNCT05184712
What this trial is testing

Phase 3 Clinical Study of AK112 for NSCLC Patients

Who this might be right for
Non-Squamous Non-small Cell Lung Cancer
Akeso 322
Large-scale testing (Phase 3)Ended earlyNCT02322281
What this trial is testing

TIGER-3: Open Label, Multicenter Study of Rociletinib (CO-1686) Mono Therapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR NSCLC Who Have Failed at Least One Previous EGFR-Directed TKI and Platinum-doublet Chemotherapy

Who this might be right for
Non-small Cell Lung Cancer
Clovis Oncology, Inc. 149
Testing effectiveness (Phase 2)UnknownNCT03257124
What this trial is testing

Study of AZD9291 in NSCLC Patients Harboring T790M Mutation Who Failed EGFR TKI and With Brain and/or LMS

Who this might be right for
Non-Small Cell Lung Cancer With EGFR T790M MutationWith Brain and/or Leptomeningeal MetastasisFailed Tyrosine Kinase Inhibitors
Samsung Medical Center 80
Testing effectiveness (Phase 2)Ended earlyNCT02078960
What this trial is testing

Evaluate the Pharmacokinetics, Safety,and Efficacy of Omacetaxine Given Subcutaneously as a Fixed Dose in Patients With Chronic Phase (CP) or Accelerated Phase (AP) Chronic Myeloid Leukemia (CML) (Referred to as the SYNSINCT Study)

Who this might be right for
Chronic Myeloid Leukemia
Teva Branded Pharmaceutical Products R&D, Inc. 10