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Results for “Familial Hypercholesterolaemia”

311 trials

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Showing 20 of 311 results

Not applicableLooking for participantsNCT06546137
What this trial is testing

National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

Who this might be right for
Cardiomyopathy, HypertrophicCardiomyopathy, DilatedCardiomyopathy Restrictive+11 more
Hospital do Coracao 1,211
Large-scale testing (Phase 3)Study completedNCT05238519
What this trial is testing

Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH)

Who this might be right for
Familial HypercholesterolemiaCholesterol, ElevatedGenetic Disease
Essentia Health 257
Not applicableLooking for participantsNCT06833944
What this trial is testing

High Intensity Interval Training in the Treatment of Familial Hypercholesterolemia (UPPA-FH)

Who this might be right for
Familiar Hypercholesterolemia
Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental 75
Large-scale testing (Phase 3)Study completedNCT04031742
What this trial is testing

Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 18
Not applicableActive Not RecruitingNCT04101149
What this trial is testing

Genetic Causes of Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Region Örebro County 150
Early research (Phase 1)Ended earlyNCT01350960
What this trial is testing

Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FH

Who this might be right for
Hypercholesterolemia
Santaris Pharma A/S 24
Not applicableUnknownNCT02517944
What this trial is testing

MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Institute of Cardiometabolism and Nutrition, France 110
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Not applicableUnknownNCT02865694
What this trial is testing

Developing and Implementing Familial Hypercholesterolemia Registry

Who this might be right for
Familial Hypercholesterolemia
Isfahan University of Medical Sciences 500
Not applicableStudy completedNCT07023445
What this trial is testing

Patterns of Inclisiran Use in the Real World: An Analysis of US Databases

Who this might be right for
Atherosclerotic Cardiovascular DiseaseFamilial Hypercholesterolemia
Novartis Pharmaceuticals 37,688
Not applicableUnknownNCT05271305
What this trial is testing

Pilot Study for a National Screening for Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Centre Hospitalier du Luxembourg 2,000
Not applicableLooking for participantsNCT02009345
What this trial is testing

Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada

Who this might be right for
Familial HypercholesterolemiaLipid Disorder
McGill University Health Centre/Research Institute of the McGill University Health Centre 6,000
Not applicableEnrolling By InvitationNCT06112327
What this trial is testing

Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease

Who this might be right for
Atherosclerotic Cardiovascular DiseaseHeterozygous Familial HypercholesterolemiaHypercholesterolemia
Verve Therapeutics, Inc. 116
Testing effectiveness (Phase 2)Study completedNCT01515241
What this trial is testing

Exploratory Study of Plaque Regression

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Cerenis Therapeutics, SA 10
Not applicableStudy completedNCT02750527
What this trial is testing

Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, Germany

Who this might be right for
Type 1 DiabetesFamilial Hypercholesterolemia
Kinderkrankenhaus auf der Bult 13,049
Large-scale testing (Phase 3)Study completedNCT06005597
What this trial is testing

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more
NewAmsterdam Pharma 407
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Large-scale testing (Phase 3)UnknownNCT04759534
What this trial is testing

Application of PCSK9 Inhibitors in Patients With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Efficacy and SafetyHeterozygous Familial HypercholesterolemiaPCSK9
Shenzhen People's Hospital 20
Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
Early research (Phase 1)Study completedNCT03747224
What this trial is testing

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Arrowhead Pharmaceuticals 93
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