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Results for “Familial Hypercholesterolaemia”

291 trials

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Showing 20 of 291 results

Testing effectiveness (Phase 2)Looking for participantsNCT04941599
What this trial is testing

2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
Vanderbilt University Medical Center 72
Not applicableStudy completedNCT03799185
What this trial is testing

Dyslipidemia Prevalence, Perception, Treatment, and Awareness in the Tunisian Population

Who this might be right for
DyslipidemiasAtherosclerosisHouseholds+1 more
Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose 13,610
Testing effectiveness (Phase 2)Study completedNCT02048410
What this trial is testing

Efficacy of a New Symbiotic Formulation in Children With Familial Hypercholesterolemia

Who this might be right for
DyslipidemiaFamilial Hypercholesterolemia
Federico II University 40
Not applicableLooking for participantsNCT06535542
What this trial is testing

Integrating Whole Genome Sequencing and Digital Twins Into the Management of Hypercholesterolemia in Emiratis

Who this might be right for
Hypercholesterolemia, Autosomal DominantHypercholesterolemia, Autosomal RecessiveFamilial Combined Hypercholesterolemia
Abu Dhabi Health Services Company 40
Testing effectiveness (Phase 2)Study completedNCT01576484
What this trial is testing

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 58
Not applicableUnknownNCT00924274
What this trial is testing

Effect of Rapeseed Oil and Sunflower Oil

Who this might be right for
Familial Hypercholesterolemia
Medical University of Vienna 24
Large-scale testing (Phase 3)Study completedNCT01623115
What this trial is testing

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Who this might be right for
Hypercholesterolemia
Sanofi 486
Not applicableLooking for participantsNCT01109368
What this trial is testing

The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Rogosin Institute 60
Not applicableUnknownNCT05271305
What this trial is testing

Pilot Study for a National Screening for Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Centre Hospitalier du Luxembourg 2,000
Not applicableLooking for participantsNCT06362473
What this trial is testing

Lipid Transport Disorder Italian Genetic Record (LIPIGEN)

Who this might be right for
Familial HypercholesterolemiaGenetic Disorder
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 10,000
Testing effectiveness (Phase 2)Study completedNCT00941603
What this trial is testing

Phase 2 Dose-Ranging Efficacy and Safety Trial of SCH 900271 in Participants With Primary Hypercholesterolemia or Mixed Hyperlipidemia (P05675)

Who this might be right for
Primary HypercholesterolemiaMixed Hyperlipidemia
Merck Sharp & Dohme LLC 619
Large-scale testing (Phase 3)Ended earlyNCT01410383
What this trial is testing

Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of Care

Who this might be right for
Heterozygous Familial Hypercholesterolaemia
Karo Bio AB 236
Large-scale testing (Phase 3)Study completedNCT00136981
What this trial is testing

Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 800
Testing effectiveness (Phase 2)Study completedNCT04666298
What this trial is testing

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 312
Large-scale testing (Phase 3)Study completedNCT03885921
What this trial is testing

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Who this might be right for
Hypercholesterolemia
Organon and Co 44
Large-scale testing (Phase 3)Study completedNCT02226198
What this trial is testing

Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 20
Not applicableLooking for participantsNCT06331195
What this trial is testing

An Adapted Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Familial Hypercholesterolemia (DICA-FH)

Who this might be right for
Familial Hypercholesterolemia
Hospital do Coracao 300
Testing effectiveness (Phase 2)Study completedNCT02963311
What this trial is testing

ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Medicines Company 9
Testing effectiveness (Phase 2)UnknownNCT04455581
What this trial is testing

Determine the Safety, Tolerability, and Efficacy of SHR-1209 in Patients With Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Jiangsu HengRui Medicine Co., Ltd. 8
Not applicableUnknownNCT01577056
What this trial is testing

Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils

Who this might be right for
HypertriglyceridaemiaFamilial Hypercholesterolaemia
The University of Western Australia 30
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