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Results for “Familial Hypercholesterolemia”

298 trials

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Showing 20 of 298 results

Very early researchStudy completedNCT03832985
What this trial is testing

Pediatric Reporting of Adult-Onset Genomic Results

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeLynch SyndromeFamilial Hypercholesterolemia
Geisinger Clinic 427
Large-scale testing (Phase 3)Study completedNCT02107898
What this trial is testing

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

Who this might be right for
Hypercholesterolemia
Sanofi 216
Large-scale testing (Phase 3)Ended earlyNCT00092833
What this trial is testing

Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Who this might be right for
Hypercholesterolemia, FamilialLipid Metabolism, Inborn Errors
Organon and Co 49
Not applicableStudy completedNCT02976818
What this trial is testing

Lp(a) and Aortic Valve Calcification

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Laval University 173
Not applicableStudy completedNCT03110432
What this trial is testing

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry

Who this might be right for
DyslipoproteinemiasHypercholesterolemia, FamilialFamilial Hypercholesterolemia - Homozygous+1 more
GWT-TUD GmbH 1,695
Testing effectiveness (Phase 2)Study completedNCT01556906
What this trial is testing

Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 6
Not applicableStudy completedNCT03640234
What this trial is testing

Return of Actionable Variants Empirical Study

Who this might be right for
Familial Hypercholesterolemia
Mayo Clinic 418
Not applicableStudy completedNCT07023445
What this trial is testing

Patterns of Inclisiran Use in the Real World: An Analysis of US Databases

Who this might be right for
Atherosclerotic Cardiovascular DiseaseFamilial Hypercholesterolemia
Novartis Pharmaceuticals 37,688
Not applicableStudy completedNCT02462655
What this trial is testing

Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Laval University 9
Large-scale testing (Phase 3)Study completedNCT02748057
What this trial is testing

A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Organon and Co 135
Large-scale testing (Phase 3)Looking for participantsNCT06568471
What this trial is testing

A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia

Who this might be right for
HypercholesterolemiaDyslipidemiasPrimary Hypercholesterolemia+4 more
Hasten Biopharmaceutical Co., Ltd. 210
Large-scale testing (Phase 3)Study completedNCT01588496
What this trial is testing

Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities

Who this might be right for
Homozygous Familial Hypercholesterolemia
Amgen 58
Not applicableStudy completedNCT05430191
What this trial is testing

Equitable Implementation of Cascade Screening for Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Northwestern University 22
Not applicableStudy completedNCT02808403
What this trial is testing

Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in Japan

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Amgen 6,000
Not applicableLooking for participantsNCT06439654
What this trial is testing

Atlantic Lipid Lowering Treatment Optimization Program

Who this might be right for
Familial HypercholesterolemiaLipoprotein Types--Lp System Lp(A) HyperlipoproteinemiaApolipoprotein B 100, Familial Defective+2 more
Atlantic Health System 250
Early research (Phase 1)Study completedNCT05851066
What this trial is testing

A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Visirna Therapeutics HK Limited 36
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Testing effectiveness (Phase 2)Study completedNCT02890992
What this trial is testing

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolaemia
Sanofi 42
Large-scale testing (Phase 3)Study completedNCT00827606
What this trial is testing

Atorvastatin Three Year Pediatric Study

Who this might be right for
Familial Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 272
Not applicableUnknownNCT03597958
What this trial is testing

Genetic Causes of Hypercholesterolaemia in the Emirati Population

Who this might be right for
Familial Hypercholesterolemia
Imperial College London Diabetes Centre 1,000
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