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Results for “Familial Hypercholesterolemia - Heterozygous”

86 trials

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Showing 20 of 86 results

Testing effectiveness (Phase 2)Study completedNCT01576484
What this trial is testing

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 58
Large-scale testing (Phase 3)Study completedNCT01623115
What this trial is testing

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Who this might be right for
Hypercholesterolemia
Sanofi 486
Large-scale testing (Phase 3)Ended earlyNCT01410383
What this trial is testing

Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of Care

Who this might be right for
Heterozygous Familial Hypercholesterolaemia
Karo Bio AB 236
Large-scale testing (Phase 3)Study completedNCT00136981
What this trial is testing

Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 800
Testing effectiveness (Phase 2)Study completedNCT04666298
What this trial is testing

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 312
Large-scale testing (Phase 3)Study completedNCT01968980
What this trial is testing

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Pfizer 370
Not applicableStudy completedNCT06389825
What this trial is testing

Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia.

Who this might be right for
Familial HypercholesterolemiaNutrition, HealthyCholesterol, Elevated
Laval University 11
Large-scale testing (Phase 3)Study completedNCT03397121
What this trial is testing

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial HypercholesterolemiaElevated Cholesterol
The Medicines Company 482
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Large-scale testing (Phase 3)Study completedNCT02666664
What this trial is testing

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Diseases
Esperion Therapeutics, Inc. 2,230
Very early researchNot Yet RecruitingNCT07353398
What this trial is testing

Early-phase Study of ART002g1 Injection in HeFH: Safety, Tolerability and Preliminary Efficacy

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 24
Large-scale testing (Phase 3)Study completedNCT05325203
What this trial is testing

Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH).

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Shanghai Junshi Bioscience Co., Ltd. 135
Large-scale testing (Phase 3)Study completedNCT05142722
What this trial is testing

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+2 more
NewAmsterdam Pharma 2,530
Large-scale testing (Phase 3)Study completedNCT00654446
What this trial is testing

IIIb 6 Week Open Label Multicentre Rosuvastatin & Simvastatin

Who this might be right for
Fredrickson Type IIa & Type IIb Dyslipidaemia
AstraZeneca 442
Not applicableLooking for participantsNCT06958315
What this trial is testing

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study

Who this might be right for
Atherosclerotic Vascular DiseaseHeterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 200
Not applicableStudy completedNCT03563547
What this trial is testing

Effects of Soy Protein on Cholesterol Levels in Children Affected With Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Austrian Academic Institute for Clinical Nutrition 34
Large-scale testing (Phase 3)Study completedNCT00827606
What this trial is testing

Atorvastatin Three Year Pediatric Study

Who this might be right for
Familial Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 272
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Testing effectiveness (Phase 2)Ended earlyNCT00079859
What this trial is testing

Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy

Who this might be right for
Familial Hypercholesterolemia
Medical Research Laboratories International 120
Large-scale testing (Phase 3)Study completedNCT00355615
What this trial is testing

PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin

Who this might be right for
Familial Hypercholesterolemia
AstraZeneca 173
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