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Results for “Familial Hypercholesterolemia - Homozygous”

79 trials

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Showing 20 of 79 results

Large-scale testing (Phase 3)Ended earlyNCT00092833
What this trial is testing

Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Who this might be right for
Hypercholesterolemia, FamilialLipid Metabolism, Inborn Errors
Organon and Co 49
Not applicableStudy completedNCT03110432
What this trial is testing

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry

Who this might be right for
DyslipoproteinemiasHypercholesterolemia, FamilialFamilial Hypercholesterolemia - Homozygous+1 more
GWT-TUD GmbH 1,695
Testing effectiveness (Phase 2)Study completedNCT01556906
What this trial is testing

Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 6
Not applicableStudy completedNCT02462655
What this trial is testing

Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Laval University 9
Large-scale testing (Phase 3)Study completedNCT01588496
What this trial is testing

Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities

Who this might be right for
Homozygous Familial Hypercholesterolemia
Amgen 58
Not applicableActive Not RecruitingNCT06275724
What this trial is testing

Specified Drug-use Survey of Leqvio for s.c. Injection.

Who this might be right for
Familial HypercholesterolaemiaHypercholesterolaemia
Novartis Pharmaceuticals 585
Not applicableUnknownNCT04080050
What this trial is testing

A Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
REGENXBIO Inc. 8
Testing effectiveness (Phase 2)Study completedNCT02472535
What this trial is testing

Study to Evaluate the Effects of MBX-8025 in Patients With HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
Gilead Sciences 13
Testing effectiveness (Phase 2)Study completedNCT02722408
What this trial is testing

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Who this might be right for
Hypercholesteremia
NeuroBo Pharmaceuticals Inc. 8
Testing effectiveness (Phase 2)Study completedNCT00477594
What this trial is testing

Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 21
Not applicableStudy completedNCT01878604
What this trial is testing

Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Central South University 5
Large-scale testing (Phase 3)Active Not RecruitingNCT05682378
What this trial is testing

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies

Who this might be right for
Heterozygous or Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 131
Large-scale testing (Phase 3)Study completedNCT02173158
What this trial is testing

Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Aegerion Pharmaceuticals, Inc. 9
Testing effectiveness (Phase 2)Study completedNCT02963311
What this trial is testing

ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Medicines Company 9
Not applicableLooking for participantsNCT06832371
What this trial is testing

Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)Major Adverse Cardiovascular Events (MACE)Dyslipidemia
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 72
Large-scale testing (Phase 3)Study completedNCT00943306
What this trial is testing

Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 19
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07133815
What this trial is testing

Evaluate the Long-term Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Beijing Suncadia Pharmaceuticals Co., Ltd 55
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Not applicableStudy completedNCT01070966
What this trial is testing

Vytorin Reexamination Study (0653A-174)

Who this might be right for
Primary Hypercholesterolemia and Homozygous Familial Hypercholesterolemia (HoFH)
Organon and Co 2,089
Not applicableStudy completedNCT03234127
What this trial is testing

Study of cardiovAscular Contrasted Phenotypes in Patients With FamIliaI hypercholesteRolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Nantes University Hospital 562
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