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Results for “Familial Hypercholesterolemia - Homozygous”

85 trials

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Showing 20 of 85 results

Large-scale testing (Phase 3)Study completedNCT04031742
What this trial is testing

Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 18
Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
Not applicableStudy completedNCT02462655
What this trial is testing

Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Laval University 9
Testing effectiveness (Phase 2)Study completedNCT01412034
What this trial is testing

Effect of CER-001 on Plaque Volume in Homozygous Familial Hypercholesterolemia (HoFH) Subjects

Who this might be right for
Homozygous Familial Hypercholesterolemia
Cerenis Therapeutics, SA 23
Testing effectiveness (Phase 2)Study completedNCT00280995
What this trial is testing

Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Who this might be right for
Hypercholesterolemia, Familial
Kastle Therapeutics, LLC 12
Large-scale testing (Phase 3)Study completedNCT03851705
What this trial is testing

Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 56
Not applicableStudy completedNCT01070966
What this trial is testing

Vytorin Reexamination Study (0653A-174)

Who this might be right for
Primary Hypercholesterolemia and Homozygous Familial Hypercholesterolemia (HoFH)
Organon and Co 2,089
Large-scale testing (Phase 3)Active Not RecruitingNCT07037771
What this trial is testing

Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 70
Not applicableStudy completedNCT00704444
What this trial is testing

A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)

Who this might be right for
HypercholesterolemiaFamilial HypercholesterolemiaHomozygous Sitosterolemia
Organon and Co 11,332
Large-scale testing (Phase 3)Study completedNCT02173158
What this trial is testing

Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Aegerion Pharmaceuticals, Inc. 9
Early research (Phase 1)Looking for participantsNCT07491172
What this trial is testing

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Who this might be right for
CardiovascularMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG 90
Testing effectiveness (Phase 2)Study completedNCT02472535
What this trial is testing

Study to Evaluate the Effects of MBX-8025 in Patients With HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
Gilead Sciences 13
Not applicableStudy completedNCT00001204
What this trial is testing

Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers

Who this might be right for
Homozygous Familial Hypercholesterolemic
National Heart, Lung, and Blood Institute (NHLBI) 73
Very early researchLooking for participantsNCT06125847
What this trial is testing

NGGT006 Gene Therapy for Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
First Affiliated Hospital Xi'an Jiaotong University 21
Large-scale testing (Phase 3)Study completedNCT02226198
What this trial is testing

Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 20
Testing effectiveness (Phase 2)Study completedNCT03933293
What this trial is testing

Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akeso 10
Testing effectiveness (Phase 2)Study completedNCT02265952
What this trial is testing

Study of REGN1500 in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 9
Testing effectiveness (Phase 2)UnknownNCT04455581
What this trial is testing

Determine the Safety, Tolerability, and Efficacy of SHR-1209 in Patients With Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Jiangsu HengRui Medicine Co., Ltd. 8
Large-scale testing (Phase 3)Study completedNCT03884452
What this trial is testing

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)

Who this might be right for
Familial Hypercholesterolemia
Organon and Co 50
Not applicableStudy completedNCT03110432
What this trial is testing

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry

Who this might be right for
DyslipoproteinemiasHypercholesterolemia, FamilialFamilial Hypercholesterolemia - Homozygous+1 more
GWT-TUD GmbH 1,695
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