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Results for “Fibrotic Disease”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07321860
What this trial is testing

This Study Evaluates the Safety, Target Engagement, and Preliminary Efficacy of Galunisertib (TGF-βR1/ALK5 Inhibitor)Combined With Nerandomilast (PDE4 Inhibitor) in GREM2-positive ALS, a Biomarker-defined Subgroup Hypothesized to Reflect Heightened TGF-β/SMAD-driven Astrocytic and Fibrotic Signaling

Who this might be right for
ALS (Amyotrophic Lateral Sclerosis)
Gipfel Life Sciences GmbH 60
Not applicableLooking for participantsNCT07419178
What this trial is testing

A New Diagnostic Algorithm to Non-invasively Track Fibrotic Changes in Myeloproliferative Neoplasms Based on C-C Chemokine Receptor 2 Detection. From Flow Cytometry to the Development of Targeted Positron Emission Tomography Molecular Imaging. Pre-clinical Studies and First In-human Proof of Concept

Who this might be right for
Myelofibrosis (MF)
Azienda Ospedaliero-Universitaria di Parma 265
Not applicableStudy completedNCT01781793
What this trial is testing

Mechanisms of Exertional Dyspnea in Fibrotic Interstitial Lung Disease

Who this might be right for
Lung; Disease, Interstitial, With Fibrosis
University of British Columbia 20
Testing effectiveness (Phase 2)UnknownNCT04988815
What this trial is testing

Ropeginterferon Alfa 2b for Early Myelofibrosis

Who this might be right for
Primary Myelofibrosis, Prefibrotic StageMyelofibrosis
The University of Hong Kong 50
Not applicableStudy completedNCT03410966
What this trial is testing

Atrial Fibrillation Ablation

Who this might be right for
Atrial FibrillationHeart Failure, Diastolic
University of Campania Luigi Vanvitelli 150
Post-approval studies (Phase 4)Looking for participantsNCT06479603
What this trial is testing

RCT of Nintedanib in Fibrotic Sarcoidosis

Who this might be right for
Sarcoidosis, Pulmonary
Post Graduate Institute of Medical Education and Research, Chandigarh 120
Not applicableStudy completedNCT02596841
What this trial is testing

Lung Diffusing Capacity for Nitric Oxide as a Marker of Fibrotic Changes in Idiopathic Interstitial Pneumonias

Who this might be right for
Usual Interstitial PneumoniaNonspecific Interstitial Pneumonia
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy 60
Not applicableLooking for participantsNCT07152431
What this trial is testing

Fibrosis Associated Protein Inhibitor (FAPI) Radiotracer-based Imaging to Identify Fibrotic Intestinal Crohn's Disease

Who this might be right for
Crohn Disease
University of Edinburgh 30
Testing effectiveness (Phase 2)Study completedNCT00043303
What this trial is testing

Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis

Who this might be right for
Liver FibrosisCirrhosis
InterMune 502
Not applicableLooking for participantsNCT06732674
What this trial is testing

Home Based Clinical Management of Interstitial Lung Disease in Systemic Rheumatic Diseases

Who this might be right for
Interstitial Lung Disease with Progressive Fibrotic Phenotype in Diseases Classified ElsewhereSystemic Sclerosis PulmonaryDermatomyositis+3 more
Oslo University Hospital 218
Not applicableLooking for participantsNCT07482917
What this trial is testing

Optimizing the Diagnostic Journey in Interstitial Lung Disease: The OPTIMIZE-ILD-1 Trial

Who this might be right for
Interstitial Lung Disease (ILD)Suspected Interstitial Lung DiseaseFibrotic Interstitial Lung Disease+2 more
Hospital de Granollers 92
Very early researchEnrolling By InvitationNCT07358234
What this trial is testing

Comparison of Eohilia With Dupixent on Esophagus Diameter in Patients With Eosinophilic Esophagitis.

Who this might be right for
Eosinophilic Esophagitis (EoE)
Mayo Clinic 60
Not applicableStudy completedNCT07129707
What this trial is testing

Nasal High-flow Oxygen Therapy During Acute Exercise in Fibrotic Interstitial Lung Disease

Who this might be right for
Interstitial Lung Disease (ILD)
Dieulefit Santé Centre de Réadaptation 15
Not applicableStudy completedNCT02477462
What this trial is testing

Identification of Inflammatory and Fibrotic Biomarkers in PBC and NAFLD Patients

Who this might be right for
Primary Biliary Cirrhosis
University of California, Davis 124
Large-scale testing (Phase 3)Active Not RecruitingNCT06468033
What this trial is testing

P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk

Who this might be right for
Primary MyelofibrosisMyeloproliferative Neoplasm
PharmaEssentia 160
Very early researchUnknownNCT04831034
What this trial is testing

68Ga-FAPI PET/CT in Patients With Various Fibrotic Disease

Who this might be right for
FibrosisPositron-Emission Tomography
First Affiliated Hospital of Fujian Medical University 500
Not applicableLooking for participantsNCT06326957
What this trial is testing

Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE)

Who this might be right for
Chronic Obstructive Pulmonary DiseaseBronchiectasisInterstitial Lung Disease+5 more
King's College Hospital NHS Trust 246
Not applicableNot Yet RecruitingNCT07770399
What this trial is testing

Biological Profile of Primary and Secondary Lymphedema: Inflammatory, Endothelial, Metabolic, Lymphatic, and Fibrotic Markers

Who this might be right for
Primary LymphedemaSecondary Lymphedema
University Medical Centre Ljubljana 90
Not applicableStudy completedNCT05648734
What this trial is testing

Anti-Inflammatory and Anti-Fibrotic Drugs in Post COVID-19 Pulmonary Fibrosis

Who this might be right for
Post-COVID-19 SyndromeLung Fibrosis
Mansoura University 200
Post-approval studies (Phase 4)Ended earlyNCT03388255
What this trial is testing

Efficacy and Safety of PLACENTEX ® i.m. in Patients With Scleroderma Diseases

Who this might be right for
Scleroderma Disease
Mastelli S.r.l 25
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