Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “First Line Chemotherapy”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT03462251
What this trial is testing

Ribociclib and Endocrine Therapy or Chemotherapy With or Without Bevacizumab for Metastatic Breast Cancer in First Line

Who this might be right for
Breast CancerHormone Receptor Positive TumorHER 2 Negative Breast Cancer
iOMEDICO AG 41
Not applicableStudy completedNCT01963351
What this trial is testing

Bevacizumab in Combination With Chemotherapy in Patients With Advanced or Recurrent Non-squamous NSCLC

Who this might be right for
Non-small Cell Lung CancerUnresectable Malignant Neoplasm
University of Athens 150
Not applicableActive Not RecruitingNCT05683977
What this trial is testing

A French Real-life Study: EvaluatioN of durvALumab Utilization and Effectiveness for First Line Extensive Stage Small Cell Lung Cancer.

Who this might be right for
Small Cell Lung Carcinoma
AstraZeneca 254
Testing effectiveness (Phase 2)UnknownNCT03701373
What this trial is testing

Maintenance Treatment With S-1 in Gastric Cancer Patients

Who this might be right for
Gastric Cancer Stage IVCancer of Stomach
Sun Yat-sen University 200
Testing effectiveness (Phase 2)WithdrawnNCT00634894
What this trial is testing

Femara (Letrozole) Versus Placebo for Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Ovarian CancerFallopian Tube CancerPeritoneal Cancer
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)UnknownNCT04619537
What this trial is testing

A Trial of Anlotinib Combined With Docetaxel in Patients With Wild-type Advanced Non-squamous Non Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Shandong Cancer Hospital and Institute 42
Testing effectiveness (Phase 2)Study completedNCT02181556
What this trial is testing

Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Federation Francophone de Cancerologie Digestive 41
Testing effectiveness (Phase 2)Study completedNCT00059722
What this trial is testing

This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Genzyme, a Sanofi Company 160
Not applicableUnknownNCT04758481
What this trial is testing

Consolidation Conventional Radiotherapy + Stereotactic Body Radiotherapy at 3 Months After First-line Chemotherapy in Stage IV Oligometastatic Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
University Hospital Ostrava 20
Large-scale testing (Phase 3)Looking for participantsNCT06669013
What this trial is testing

Chemo-immunotherapy in Patients Under 18 Years of Age With Bone and Soft Tissue Sarcomas

Who this might be right for
Bone SarcomaEmbryonal RhabdomyosarcomaAlveolar Rhabdomyosarcoma
N.N. Petrov National Medical Research Center of Oncology 40
Large-scale testing (Phase 3)Looking for participantsNCT07478991
What this trial is testing

Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients (VENP-A-QUI)

Who this might be right for
Acute Myeloid Leukemia, Adult
PETHEMA Foundation 376
Testing effectiveness (Phase 2)Ended earlyNCT01198548
What this trial is testing

High-Dose Cholecalciferol in Treating Patients Receiving Combination Chemotherapy and Bevacizumab as First-Line Therapy For Metastatic Colorectal Cancer

Who this might be right for
Stage IV Colon CancerStage IV Rectal Cancer
Roswell Park Cancer Institute 10
Testing effectiveness (Phase 2)Study completedNCT02414685
What this trial is testing

First Line TIP in Poor Prognosis TGCTs.

Who this might be right for
Germ Cell Tumor
National Cancer Institute, Slovakia 19
Testing effectiveness (Phase 2)Ended earlyNCT03251417
What this trial is testing

Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Peking University 11
Testing effectiveness (Phase 2)Study completedNCT00217698
What this trial is testing

Gefitinib as First-Line Therapy Followed by Gemcitabine and Cisplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
Swiss Cancer Institute 63
Testing effectiveness (Phase 2)UnknownNCT03641976
What this trial is testing

Bevacizumab, Infusional Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan (A-FOLFOXIRI) Compared With Bevacizumab, Infusional Fluorouracil, Leucovorin, and Irinotecan/Oxaliplatin (A-FOLFIRI/FOLFOX) as First-line Treatment for Metastatic Right-sided Colon Cancer

Who this might be right for
Unresectable Metastatic Right-sided Colon Cancer Starting First-line Combination ChemotherapyUnresectable Metastatic Right-sided Colon Cancer, Stage IV
Yonsei University 120
Large-scale testing (Phase 3)Ended earlyNCT00526643
What this trial is testing

CAPPA-2: Cisplatin Added to Gemcitabine in Poor Performance Advanced NSCLC Patients

Who this might be right for
Non-Small Cell Lung Cancer
National Cancer Institute, Naples 57
Testing effectiveness (Phase 2)Active Not RecruitingNCT03830918
What this trial is testing

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

Who this might be right for
Advanced Malignant Solid NeoplasmExtensive Stage Lung Small Cell CarcinomaStage III Lung Cancer AJCC v8+6 more
Jonsson Comprehensive Cancer Center 59
Large-scale testing (Phase 3)Study completedNCT00961415
What this trial is testing

AVAPERL1 Study: A Study of Avastin (Bevacizumab) With or Without Pemetrexed as Maintenance Therapy After Avastin in First Line in Patients With Non-Squamous Non-Small Cell Lung Cancer

Who this might be right for
Non-Squamous Non-Small Cell Lung Cancer
Hoffmann-La Roche 376
Testing effectiveness (Phase 2)WithdrawnNCT04731740
What this trial is testing

Pembrolizumab and Lenvatinib/Chemotherapy for Poorly Differentiated/Anaplastic Thyroid Cancer

Who this might be right for
Metastatic Thyroid Gland CarcinomaPoorly Differentiated Thyroid Gland CarcinomaThyroid Gland Anaplastic Carcinoma by AJCC V8 Stage
Saint Petersburg State University, Russia
Next Page