Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “First Line Chemotherapy”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07738159
What this trial is testing

Iparomlimab and Tuvonralimab (QL1706) Plus Lenvatinib and Chemotherapy for Extrapulmonary Neuroendocrine Carcinoma

Who this might be right for
Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)QL1706Lenvatinib+1 more
West China Hospital 92
Testing effectiveness (Phase 2)WithdrawnNCT01137994
What this trial is testing

A Phase II, Randomized, Open-label Study of Lapatinib Plus Chemotherapy Versus Trastuzumab Plus Chemotherapy in HER2-positive and p95HER2-positive Metastatic Breast Cancer

Who this might be right for
Neoplasms, Breast
GlaxoSmithKline
Testing effectiveness (Phase 2)UnknownNCT02504229
What this trial is testing

DC-CIK In Combination With Chemotherapy ( Gio / Oxaliplatin or Cisplatin ) Versus First-line Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma Randomized Controlled Phase II Clinical Study of Treatment

Who this might be right for
Gastric Cancer
Beijing Biohealthcare Biotechnology Co.,Ltd 80
Testing effectiveness (Phase 2)Ended earlyNCT02161419
What this trial is testing

RONICICLIB / Placebo in Combination With Chemotherapy in Small Cell Lung Cancer

Who this might be right for
Small Cell Lung Carcinoma
Bayer 142
Large-scale testing (Phase 3)UnknownNCT02383030
What this trial is testing

Fulvestrant as Maintenance Therapy After First-line Chemotherapy in HER2 - Postmenopausal MBC Patients

Who this might be right for
Metastatic Breast Cancer
Consorzio Oncotech 156
Testing effectiveness (Phase 2)Study completedNCT02129257
What this trial is testing

Clinical Trial of Combination Chemotherapy With Aflibercept in Patients With Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Hellenic Cooperative Oncology Group 73
Testing effectiveness (Phase 2)Looking for participantsNCT06669572
What this trial is testing

Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial Treatment

Who this might be right for
Carcinoma, Squamous CellAnorectal Cancer
University of Chicago 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07271602
What this trial is testing

Randomized, Controlled Trial of QL1706 Plus Chemotherapy and Quad Shot for Driver Gene-negative Advanced Non-small Cell Lung Cancer.

Who this might be right for
Non Small Cell Lung CancerImmunotherapyRadiotherapy+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 104
Not applicableUnknownNCT05729737
What this trial is testing

Radiographic Response to Chemotherapy in Unresected Localized Pancreatic Cancer

Who this might be right for
Pancreatic CancerUltrasonographyFirst-line Chemotherapy
Peking Union Medical College Hospital 100
Large-scale testing (Phase 3)Active Not RecruitingNCT05502237
What this trial is testing

Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Gilead Sciences 1,021
Testing effectiveness (Phase 2)Study completedNCT00147537
What this trial is testing

Combination Study Of CP-751,871 With Paclitaxel And Carboplatin In Advanced Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Pfizer 282
Large-scale testing (Phase 3)Looking for participantsNCT07702032
What this trial is testing

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)

Who this might be right for
Left-sided Colorectal Cancer
Genmab 960
Testing effectiveness (Phase 2)UnknownNCT01693432
What this trial is testing

Docetaxel and S-1 for Advanced Esophageal Cancer

Who this might be right for
Esophageal Neoplasms
Hallym University Medical Center 37
Testing effectiveness (Phase 2)Ended earlyNCT03790111
What this trial is testing

A Safety and Efficacy Study of XERMELO® + First-line Chemotherapy in Patients With Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer (BTC)
TerSera Therapeutics LLC 53
Testing effectiveness (Phase 2)Study completedNCT02414009
What this trial is testing

Study to Compare CAPTEM vs FOLFIRI as Second Line Treatment in Advanced, Colorectal Cancer Patients

Who this might be right for
Metastatic Colorectal Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 82
Large-scale testing (Phase 3)Looking for participantsNCT06956001
What this trial is testing

Firmonertinib Versus Platinum Based Chemotherapy as First-line Treatment for NSCLC With EGFR PACC or EGFR l861q Mutation

Who this might be right for
EGFRNSCLC (Advanced Non-small Cell Lung Cancer)
Allist Pharmaceuticals, Inc. 300
Large-scale testing (Phase 3)Study completedNCT02184195
What this trial is testing

Olaparib in gBRCA Mutated Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum-Based Chemotherapy

Who this might be right for
Germline BRCA1/2 Mutations andMetastatic Adenocarcinoma of the Pancreas
AstraZeneca 154
Large-scale testing (Phase 3)Ended earlyNCT00442026
What this trial is testing

Randomized Trial of Docetaxel and Gemcitabine Versus Gemcitabine in Elderly Patients With NSCLC

Who this might be right for
Non-small-cell Lung Cancer
Hellenic Oncology Research Group 106
Large-scale testing (Phase 3)Study completedNCT01154140
What this trial is testing

A Clinical Trial Testing The Efficacy Of Crizotinib Versus Standard Chemotherapy Pemetrexed Plus Cisplatin Or Carboplatin In Patients With ALK Positive Non Squamous Cancer Of The Lung

Who this might be right for
Non Squamous Lung Cancer
Pfizer 343
Testing effectiveness (Phase 2)Study completedNCT00744900
What this trial is testing

Pemetrexed Plus Cisplatin for Brain Metastasis of Advanced Non - Small Cell Lung Cancer (NSCLC)

Who this might be right for
Lung Cancer
University Hospital, Brest 45
Next Page