Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “First Line Chemotherapy”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Not applicableNot Yet RecruitingNCT07543510
What this trial is testing

Low-Dose Bevacizumab and Atezolizumab Combined With TACE-HAIC in Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaAtezolizumab Plus BevacizumabTransarterial Chemoembolization
Third Affiliated Hospital, Sun Yat-Sen University 38
Testing effectiveness (Phase 2)Ended earlyNCT02173990
What this trial is testing

Aflibercept and Chemotherapy as First Line Treatment for Metastatic Colorectal Cancer Assessable With DCE-US (PULSAR).

Who this might be right for
Metastatic Colorectal Cancer
Centre Oscar Lambret 40
Not applicableUnknownNCT04858828
What this trial is testing

Investigation on Predictive Molecular Markers of Efficacy for Front-line Immunochemotherapy in Advanced NSCLC

Who this might be right for
Biomarkers
Zhou Chengzhi 200
Testing effectiveness (Phase 2)Study completedNCT02392507
What this trial is testing

Nab-Paclitaxel and Carboplatin Plus Necitumumab (LY3012211) in Participants With Stage IV Squamous NSCLC

Who this might be right for
Carcinoma, Non-Small Cell Lung Cancer (NSCLC)
Eli Lilly and Company 54
Large-scale testing (Phase 3)Not Yet RecruitingNCT05767892
What this trial is testing

YK-029A as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations

Who this might be right for
Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Suzhou Puhe Pharmaceutical Technology Co., LTD 350
Large-scale testing (Phase 3)Ended earlyNCT00047632
What this trial is testing

Safety and Efficacy of Interferon Gamma-1b Plus Chemotherapy for Ovarian and Peritoneal Cancer

Who this might be right for
Ovarian CarcinomaPeritoneal Carcinoma
InterMune 847
Early research (Phase 1)Study completedNCT02668393
What this trial is testing

Nintedanib and Weekly Docetaxel in Lung Adenocarcinoma

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 14
Large-scale testing (Phase 3)Active Not RecruitingNCT06746116
What this trial is testing

Evaluate the Use of Durvalumab in Combination With Platinum-based Chemotherapy Followed by Durvalumab With Olaparib as First-line Treatment in Advanced or Recurrent Endometrial Cancer in Spain

Who this might be right for
Advanced or Recurrent Endometrial Cancer
AstraZeneca 45
Large-scale testing (Phase 3)Looking for participantsNCT06817161
What this trial is testing

Benefit of Transcutaneous Auricular Vagus Nerve Stimulation in Improving Quality of Life in First Line Treatment of Ovarian Cancer:

Who this might be right for
Ovarian CarcinomaFirst Line ChemotherapyDigestive System Disorders
Centre Francois Baclesse 116
Testing effectiveness (Phase 2)Study completedNCT03586999
What this trial is testing

Nivolumab With Standard of Care Chemotherapy for Peripheral T Cell Lymphomas

Who this might be right for
Peripheral T Cell Lymphoma
University of Colorado, Denver 18
Large-scale testing (Phase 3)Study completedNCT00455936
What this trial is testing

First-line Gefitinib Versus Chemotherapy for Lung Adenocarcinoma in Never Smoker

Who this might be right for
Lung Cancer
National Cancer Center, Korea 315
Testing effectiveness (Phase 2)UnknownNCT01249521
What this trial is testing

Dual Targeting of Vascular Endothelial Growth Factor-A Together With Angiopoietins in Chemotherapy-naïve Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Austin Health 40
Testing effectiveness (Phase 2)UnknownNCT03986294
What this trial is testing

Second Line Treatment With Nal-IRI and S1 in Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 122
Large-scale testing (Phase 3)Ended earlyNCT03656536
What this trial is testing

Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma

Who this might be right for
Unresectable CholangiocarcinomaMetastatic Cholangiocarcinoma
Incyte Corporation 167
Testing effectiveness (Phase 2)Study completedNCT00416767
What this trial is testing

Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By Surgery

Who this might be right for
Gastrointestinal Carcinoid TumorIslet Cell TumorNeoplastic Syndrome
Federation Francophone de Cancerologie Digestive 20
Large-scale testing (Phase 3)Study completedNCT00243867
What this trial is testing

Taxoprexin Plus Carboplatin Treatment for Advanced Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
American Regent, Inc. 518
Testing effectiveness (Phase 2)Study completedNCT00215644
What this trial is testing

Matuzumab Treatment With Epirubicin, Cisplatin and Capecitabine (ECX) in Esophago-Gastric Cancer

Who this might be right for
Esophageal CancerGastric Cancer
Merck KGaA, Darmstadt, Germany 72
Large-scale testing (Phase 3)Looking for participantsNCT07222800
What this trial is testing

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Who this might be right for
Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System Neoplasms+7 more
Pfizer 800
Large-scale testing (Phase 3)Looking for participantsNCT06899126
What this trial is testing

Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Daiichi Sankyo 686
Testing effectiveness (Phase 2)Study completedNCT05219435
What this trial is testing

Study of NIVOLUMAB/IPILIMUMAB Maintenance in Unresectable Locally Advanced or Metastatic Urothelial Cancer

Who this might be right for
Urothelial Cancer
Spanish Oncology Genito-Urinary Group 25
Next Page