Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “First Line Metastatic Colorectal Cancer”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT06616259
What this trial is testing

First-line Treatment of MCapOX + Cetuximab Vs. MFOLFOX6 + Cetuximab for RAS/BRAF Wild-type, MSS, Unresectable Left-Sided MCRC: a Multicenter, Randomized, Controlled, Phase III Study

Who this might be right for
Colorectal Cancer (CRC)CapecitabineCetuximab
Meng Qiu 452
Testing effectiveness (Phase 2)Study completedNCT00636610
What this trial is testing

Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Genentech, Inc. 199
Testing effectiveness (Phase 2)Looking for participantsNCT04689347
What this trial is testing

5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.

Who this might be right for
Metastatic Colorectal Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 27
Testing effectiveness (Phase 2)UnknownNCT03271255
What this trial is testing

Apatinib Versus Bevacizumab in Second-line Therapy for Colorectal Cancer(ABST-C)

Who this might be right for
Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal Neoplasms+1 more
Shenzhen People's Hospital 80
Testing effectiveness (Phase 2)Study completedNCT01763307
What this trial is testing

Examine the Effect of Reconval K1 Cream to Prevent Skin Toxicity From EGFRI

Who this might be right for
Rash Due to Epidermal Growth Factor Receptor Inhibitors
Hadassah Medical Organization 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT05312398
What this trial is testing

CAPRI 2 GOIM Study: Investigate the Efficacy and Safety of a Bio-marker Driven Cetuximab-based Treatment Regimen

Who this might be right for
Metastatic Colorectal Adenocarcinoma
University of Campania Luigi Vanvitelli 219
Testing effectiveness (Phase 2)Study completedNCT00806663
What this trial is testing

FOLFIRI and Sunitinib in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerLiver Metastases
Central European Society for Anticancer Drug Research 22
Not applicableEnded earlyNCT03849950
What this trial is testing

Self-Management and Activation to Reduce Treatment-Related Toxicities (SMARTCare)

Who this might be right for
LymphomaLung CancerColo-rectal Cancer
University Health Network, Toronto 62
Testing effectiveness (Phase 2)Ended earlyNCT03524820
What this trial is testing

Cetuximab Therapy for Third Line Rechallenge in Metastatic Colorectal Cancer

Who this might be right for
Cancer of Colon
Hadassah Medical Organization 3
Testing effectiveness (Phase 2)Study completedNCT00660582
What this trial is testing

FLOX + Cetuximab (Erbitux®) for Patients With Metastatic Colorectal Cancer and Wild Type K-RAS Tumor

Who this might be right for
Metastatic Colorectal Cancer
Per Pfeiffer 152
Large-scale testing (Phase 3)Study completedNCT03206151
What this trial is testing

CMAB009 Combined With FOLFIRI First-line Treatment in Patients With RAS/BRAF Wild-type, Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Taizhou Mabtech Pharmaceutical Co.,Ltd 520
Testing effectiveness (Phase 2)WithdrawnNCT00954876
What this trial is testing

Study of Capecitabine and Cetuximab as First-Line Therapy in Patients With Metastatic Wild Type Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Translational Genomics Research Institute
Testing effectiveness (Phase 2)Study completedNCT00439517
What this trial is testing

Study to Evaluate the Efficacy and Safety of FOLFOX-4 Plus Cetuximab Versus UFOX Plus Cetuximab.

Who this might be right for
Previously Untreated Metastatic Colorectal Cancer
Merck KGaA, Darmstadt, Germany 302
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06959589
What this trial is testing

The Efficacy and Safety of IBI351, Cetuximab β Combined With FOLFIRI as First-line /IBI351, Cetuximab β as Second-line in the Treatment of KRAS G12C-mutated Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticKRAS G12C Mutation
Second Affiliated Hospital, Zhejiang University, School of Medicine 50
Testing effectiveness (Phase 2)UnknownNCT05799820
What this trial is testing

QL1706 Monotherapy or in Combination With Bevacizumab and XELOX as First-line Treatment of Unresectable Advanced or Metastatic CRC

Who this might be right for
Colorectal Carcinoma
Qilu Pharmaceutical Co., Ltd. 60
Testing effectiveness (Phase 2)Study completedNCT02337946
What this trial is testing

Safety and Efficacy Study of mFOLFOX6 + Panitumumab Combination Therapy and 5-FU/LV + Panitumumab Combination Therapy in Participants With Chemotherapy-naïve Unresectable Advanced Recurrent Colorectal Carcinoma

Who this might be right for
Colorectal Carcinoma
Takeda 164
Testing effectiveness (Phase 2)Study completedNCT01963182
What this trial is testing

Individualization of Dosage of Irinotecan in the FOLFIRI According to the Genetic Polymorphism of UGT1A1 in the First Line Treatment of Metastatic Colorectal Cancer

Who this might be right for
First Line Metastatic Colorectal Cancer
Centre Jean Perrin 47
Large-scale testing (Phase 3)Study completedNCT03231722
What this trial is testing

First Line mFOLFOXIRI + PANITUMUMAB vs mFOLFOX + PANITUMUMAB IN RAS AND BRAF WT METASTATIC COLORECTAL CANCER PATIENTS

Who this might be right for
Metastatic Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 435
Testing effectiveness (Phase 2)UnknownNCT05016869
What this trial is testing

Fruquintinib Plus Capecitabine as Maintenance Treatment of RAS / BRAF Wild-type Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Chinese Academy of Medical Sciences 48
Testing effectiveness (Phase 2)Study completedNCT02181556
What this trial is testing

Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Federation Francophone de Cancerologie Digestive 41
Next Page